A5108057065- Agricultural Science and Fertilization
- Diet, Metabolism, and Disease
- Rice Cultivation and Yield Improvement
- Liver Disease Diagnosis and Treatment
- Diet and metabolism studies
- Garlic and Onion Studies
- Geomagnetism and Paleomagnetism Studies
- Vitamin C and Antioxidants Research
- Geology and Paleoclimatology Research
- Biomedical Research and Pathophysiology
- Geological and Geochemical Analysis
- Metabolomics and Mass Spectrometry Studies
- Metabolism and Genetic Disorders
- Nuclear Structure and Function
- Graphene and Nanomaterials Applications
- Neonatal Health and Biochemistry
- Alcohol Consumption and Health Effects
- Peroxisome Proliferator-Activated Receptors
- Cardiovascular Function and Risk Factors
- Research in Cotton Cultivation
- Insect Resistance and Genetics
- Insect-Plant Interactions and Control
- Plant Growth Enhancement Techniques
- Forest ecology and management
- Mitochondrial Function and Pathology
National Institute of Pharmaceutical Education and Research
2020-2025
Translational Health Science and Technology Institute
2019-2024
Tropical Forest Research Institute
2021
SUNY Upstate Medical University
2008-2019
Indian Institute of Chemical Technology
2011
Central Institute for Cotton Research
2000-2009
Center for Rheumatology
2009
University of Calcutta
1940-2008
Bloom Fertility Centre
2008
Cleveland Clinic
2008
ABSTRACT Wound healing, especially for severe injuries, require dressings that absorb exudate, prevent infection, and support healing without causing trauma upon removal. Traditional single‐layered often fail to balance moisture retention protection, hindering optimal healing. To address this, a bilayered scaffold was fabricated comprising an electrospun hydrophilic sublayer of Pullulan/Polyvinyl alcohol (PVA)/Gum arabic blend loaded with Gentamicin solvent‐casted hydrophobic top layer...
Abstract Persistent mitochondrial hyperpolarization (MHP) and enhanced calcium fluxing underlie aberrant T cell activation death pathway selection in systemic lupus erythematosus. Treatment with rapamycin, which effectively controls disease activity, normalizes CD3/CD28-induced but fails to influence MHP, suggesting that altered is downstream or independent of dysfunction. In this article, we show activity the mammalian target rapamycin (mTOR), a sensor transmembrane potential, increased...
Type 2 diabetes mellitus, characterized by peripheral insulin resistance, is a major lifestyle disorder of the 21st Century. Raw garlic homogenate has been reported to reduce plasma glucose levels in animal models type 1 mellitus. However, no specific studies have conducted evaluate effect raw on resistance or This study was designed investigate fructose induced associated metabolic syndrome and oxidative stress diabetic rats.Male Sprague Dawley rats weighing 200-250 gm body weight were...
Although oxidative stress has been implicated in acute acetaminophen-induced liver failure and chronic cirrhosis hepatocellular carcinoma (HCC), no common underlying metabolic pathway identified. Recent case reports suggest a link between the pentose phosphate (PPP) enzyme transaldolase (TAL; encoded by TALDO1) children. Here, we show that Taldo1–/– Taldo1+/– mice spontaneously developed HCC, had increased susceptibility to failure. Oxidative livers was characterized accumulation of...
The hypoglycaemic activity of Punica granatum Linn. (Family Punicaceae) seed extract on rats made diabetic by streptozotocin (STZ) was investigated. methanol the at doses 300 and 600 mg/kg, chlorpropamide 200 mg/kg administered to STZ rats. (150, orally) caused a significant reduction blood glucose levels in induced 47% 52%, respectively, end 12 h.
The counteraction of exogenous L-proline at different concentrations with salinity (100 mM NaCl sublethal concentration) were observed on germinating rice. Supplemented 30 was shown to be the most effective; higher concentration it reduced seedling growth and K+/Na+ ratio. Thus can alleviate stress in rice seedlings.
Fertility of spermatozoa depends on maintenance the mitochondrial transmembrane potential (Deltapsi(m)), which is generated by electron-transport chain and regulated an oxidation-reduction equilibrium reactive oxygen intermediates, pyridine nucleotides, glutathione (GSH). Here, we report that male mice lacking transaldolase (TAL)(-/-) are sterile because defective forward motility. TAL(-/-) show loss Deltapsi(m) membrane integrity diminished NADPH, NADH, GSH. Mitochondria constitute major...
Lower Pennsylvanian Belden Formation carbonate rocks from Colorado were subjected to paleomagnetic, rock magnetic and geochemical studies test whether there is a connection between widespread chemical remanent magnetization (CRM), carried by authigenic magnetite, burial diagenesis. Thermal demagnetization results indicate the presence of two components natural (NRM) after removal low unblocking temperature (NRM‐250°C) remanence that interpreted be modern, viscous magnetization. An...
TAL (transaldolase) was originally described in the yeast as an enzyme of PPP (pentose phosphate pathway). However, certain organisms and mammalian tissues lack TAL, overall reason for its existence is unclear. Recently, deletion Ser171 (TALΔS171) found five patients causing inactivation, proteasome-mediated degradation complete deficiency TAL. In present study, microarray follow-up Western-blot, enzyme-activity metabolic studies TALΔS171 TD (TAL-deficient) lymphoblasts revealed co-ordinated...
Scope Cause‐effect relationship between vitamin D deficiency and cardiometabolic abnormalities remains undefined. The aim is to investigate the role of in cardiac failure, through possible involvement myocardial insulin signaling. Methods results Male SD rats ( n = 6) are fed a normal diet (Con), D‐deficient [Con(‐)], or high‐fat, high fructose (HFHFrD) for 20 weeks. Cardiac hypertrophy fetal gene program confirmed Con(‐) group. dysfunction assessed by echocardiography. Elevated renin, TGF‐β...
Significance Genome fluidity is directly associated with the emergence and evolution of many bacterial pathogens. Horizontally acquired genetic elements, which harbor fitness traits, are open source for evolution. The genome Vibrio cholerae equipped multiple mobile elements (MGEs), crucial disease development survival. present study engineered a well characterized clinical V. strain N16961 reported ( i ) stability MGEs in cholera pathogen, ii interactions between core MGEs, iii role...
ABSTRACT The study focuses on the fabrication and characterization of ciprofloxacin (CIP)/paclitaxel (PTX)‐loaded pullulan/poly(lactic‐co‐glycolic acid) (PLGA) core/sheath nanofibers using highly efficient coaxial electrocentrifugal spinning (ECS) technique. In contrast to conventional electrospinning, in‐house developed ECS setup used in this effectively tackled nozzle cleaning issue. study, with varying core‐to‐sheath ratio were fabricated, demonstrating suitable mechanical properties for...
Allylmethylsulfide (AMS) is a novel sulfur metabolite found in the garlic-fed serum of humans and animals. In present study, we have observed that AMS safe on chronic administration has potential antihypertrophic effect. Chronic for 30 days did not cause any significant differences body weight, electrocardiogram, food intake, biochemical parameters, histopathology vital organs. Single-dose pharmacokinetics suggests rapidly metabolized into Allylmethylsulfoxide (AMSO) Allylmethylsulfone (AMSO...