Blueberries possess abundant anthocyanins, which benefit eye health. The purpose of this study was to explore the protective functional role blueberry anthocyanin extract (BAE) and its predominant constituents, malvidin (Mv), malvidin-3-glucoside (Mv-3-glc), malvidin-3-galactoside (Mv-3-gal), on high glucose- (HG-) induced injury in human retinal capillary endothelial cells (HRCECs). results showed that BAE, Mv, Mv-3-glc, Mv-3-gal enhanced cell viability (P < 0.05 versus HG group at 24 h);...

Blueberry anthocyanins are considered protective of eye health because their recognized antioxidant properties. In this study, blueberry anthocyanin extract (BAE), malvidin (Mv), malvidin-3-glucoside (Mv-3-glc), and malvidin-3-galactoside (Mv-3-gal) all reduced H2O2-induced oxidative stress by decreasing the levels reactive oxygen species malondialdehyde increasing superoxide dismutase, catalase, glutathione peroxidase in human retinal pigment epithelial cells. BAE standards enhanced cell...

Abstract Background The interactions between blueberry leaf polyphenols (BLPs) and digestive enzymes were analyzed using multiple techniques to gain insights into their inhibitory effects on enzyme kinetics modes of action. Results 3‐ O ‐Caffeoylquinic acid (3‐CQA) was the most abundant compound identified. Quercetin (QR) exhibited strongest activity against α ‐amylase ( ‐AMY) ‐glucosidase ‐GLU). BLP extracts acted as typical mixed‐type inhibitors for both enzymes, showing stronger...

A novel strategy was found to develop whole-grain oats as a probiotic carrier and nutraceutical supplement targeting hypertension.

This research aimed to recover anthocyanin-rich extracts from blackberry (Rubus spp. Hull cultivar) by optimizing the processing conditions, and characterize anthocyanin individuals determine influences of optimization on enhancement antioxidant anti-hyperglycemic activities anthocyanins as natural supplements. The ethanol concentration 69.87%, HCl dosage 0.53%, solid-to-liquid ratio 1:19.06 at 47.68°C for 17.04 h were optimal obtain highest extraction yield 0.72 mg/g. By using AB-8...

Abstract A blueberry anthocyanin extract was obtained from Brightwell fruits cultivated in eastern China and the extraction purification conditions were optimized. The components of identified using ultra-performance liquid chromatography-electrospray ionization interface-mass spectrometer. antioxidant antibacterial activities fruit supernatant (BFS), crude (BCE), rich (BRE) evaluated. yield 1.79 ± 0.0014 mg/g under following optimal conditions: 1:20 solid-to-liquid ratio (v/w), 24 h, 34 °C,...

Abstract Soybean protein is of plant origin and commonly appropriate for improving the processing characteristics foods. This study aimed to explore a novel functional ingredient that contained soybean isolate (SPI) blueberry anthocyanins (BANs). The spatial conformation secondary structure SPI-BANs complexes were analyzed using circular dichroism fluorescence spectroscopy, properties investigated as well retention antioxidant activity during thermal treatments. Results showed contents free...

The transport behavior and absorption mechanism of Ala-His-Leu-Leu (AHLL) intestinal in Caco-2 cell monolayers were clarified systemically. safe absorptive concentration AHLL was 200 μg/mL, which determined by the 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide assay. permeation dependent a bidirectional transfer reached plateau at 90 min. efflux ratio above 0.5, suggesting that absorbed both active passive diffusion. apparent permeability coefficients (Papp) from apical...

The pellicle-forming yeast could cause the quality deterioration of wine. In this study, a strain Hmp-1 was isolated from spoilage blackberry wine, and identified as Pichia membranifaciens based on morphology partial nucleotide sequence 26S rDNA. effects fermentation conditions (ethanol, sulfur dioxide, sugar, temperature) growth P. Saccharomyces cerevisiae FM-S-115 (a used for wine fermentation) were investigated, respectively. results indicated that had lower resistance to these factors...

Ala-His-Leu-Leu (AHLL) was isolated and purified from the loach (Misgurnus anguillicaudatus) hydrolysate in our previous study. The aim of this study to investigate antihypertensive effects angiotensin-I-converting enzyme (ACE) inhibitory peptide AHLL spontaneously hypertensive rats (SHRs). showed good SHRs during long-term oral administration no allergic reactions or coughing were observed. After 2 months AHLL, body weight growth normal. decrements systolic blood pressure high dose (5 mg/kg...

Cordyceps militaris contains many kinds of bioactive components with the various physiological activities, but has less natural sources fruiting bodies. Compared bodies from same origin, fermented mycelia contained significantly higher amount protein, crude fat and polysaccharides. The had more total amino acids, proline (3.84 ± 0.12 g 100g<SUP>-1</SUP>), leucine (2.96 0.10 aspartic acid (2.68 0.06 100g<SUP>-1</SUP>) as top three aboundant while glutamic (3.56 0.07 (2.52 0.13 valine (2.35...

Metal ions could affect the stability of fruit wine. However, their influence on blackberry wine (BBW) has not been studied. In this study, iron, copper, chromium and nickel BBW was analyzed. The iron its main pigment cyanidin-3-O-glucoside (C3G) analyzed by comparing chromaticity, fluorescence, component. mechanism which cause C3G discoloration further After 15 days aging, added with 1 mmol/L chromium, powder showed no significant change. changed in color from red to blue after adding same...

Cell immobilization is an alternative to microencapsulation for the maintenance of cells in a liquid medium. However, artificial carriers are expensive and pose high safety risk. This study aimed evaluate potential okara, food-grade byproduct from soymilk production, as natural immobilizer L. plantarum 70810 cells. The also effects okara-immobilized on fermentation, glucosidic isoflavone bioconversion, cell resistance gastrointestinal (GI) stress. Scanning electron microscopy revealed that...