- Metabolism and Genetic Disorders
- Metabolomics and Mass Spectrometry Studies
- Liver Disease Diagnosis and Treatment
- Wound Healing and Treatments
- Proteoglycans and glycosaminoglycans research
- Advanced Drug Delivery Systems
- Chronic Kidney Disease and Diabetes
- Advancements in Transdermal Drug Delivery
- Birth, Development, and Health
- Analytical chemistry methods development
- Photodynamic Therapy Research Studies
- Bone Tissue Engineering Materials
- Dermatologic Treatments and Research
- Dental Implant Techniques and Outcomes
- Electrospun Nanofibers in Biomedical Applications
- Forensic Fingerprint Detection Methods
- Antimicrobial agents and applications
- Polymer Surface Interaction Studies
- Erythropoietin and Anemia Treatment
- Diabetic Foot Ulcer Assessment and Management
- Ion-surface interactions and analysis
- Diet and metabolism studies
- Osteoarthritis Treatment and Mechanisms
- Pharmacogenetics and Drug Metabolism
- Nanocomposite Films for Food Packaging
University of the Basque Country
2014-2024
CIC energiGUNE
2022-2023
Hyaluronic acid (HA) injectable biomaterials are currently applied in numerous biomedical areas, beyond their use as dermal fillers. However, bacterial infections and painful inflammations associated with healthcare complications that can appear after injection, restricting applicability. Fortunately, HA hydrogels also serve drug delivery platforms for the controlled release of bioactive agents a critical role control certain diseases. Accordingly, herein, were crosslinked 1 4-butanediol...
Abstract Pediatric chronic kidney disease (CKD) is a clinical condition characterized by progressive renal function deterioration. CKD diagnosis based on glomerular filtration rate, but its reliability limited, especially at the early stages. New potential biomarkers (citrulline (CIT), symmetric dimethylarginine (SDMA), S-adenosylmethionine (SAM), n-butyrylcarnitine (nC4), cis-4-decenoylcarnitine, sphingosine-1-phosphate and bilirubin) in addition to creatinine (CNN) have been proposed for...
Pediatric chronic kidney disease (CKD) is a clinical syndrome characterized by renal hypofunction occurring due to gradual and irreversible damage that can further progress over time. New biomarkers may help early diagnosis of pediatric patients suffering from CKD improve the outcome. Untargeted metabolomics based on LC-QTOF-MS has been used find new for in plasma patients. In order avoid any bias determination statistically significant entities as consequence data analysis method followed,...
A significant number of people worldwide suffers from knee osteoarthritis (KOA), a chronic and painful disease that is linked to ageing, traumatological events sports medicine. Clinical research indicates KOA exhibit an altered synovial fluid (SF) with lower endogenous hyaluronic acid (HA) concentration viscoelastic properties. Nowadays, viscosupplementation by intra-articular HA injections the most common treatment restore performance in osteoarthritic SF. In this work, TrHCROSS®,...
Prolonged sun exposure disrupts the skin’s structural, mechanical, and functional properties, accelerating aging contributing to skin disorders. To counteract these effects, we developed a formulation containing potent antioxidant, anti-inflammatory, moisturizing, reparative ingredients protect repair sun-damaged skin. The efficacy of was evaluated through in vitro, ex vivo, vivo studies. Results demonstrated that reduced oxidative stress suppressed production pro-inflammatory cytokines...
Azken urteotan, su-armen erabilera nabarmen handitu da gure gizartean eta horrek tiro egin ondoren sortutako partikulen analisirako metodologia berriak garatzea ekarri du. Krimen agertokian tiro-aztarnak (gunshot residue, GSR) osatzen dituzten konposatuen detekzio identifikazioak erabileraren ebidentzia fidagarria eskaintzen Tiro-aztarnak erretako erre gabeko multzoa da, munizioa erretzen denean sortutakoak su-armak berak, jaurtigaiak kartutxoak askatutako konposatuez osatuak. Tiro ostean,...
Giltzurrun gutxiegitasun kronikoaren (GGK) ebaluazioa egiten da iragazpen glomerularraren tasaren (IGT) bidez, eta kalkulatzen serumeko kreatininaren kontzentrazioan oinarritutako ekuazioen bidez. Hala ere, kreatinina kontzentrazioa hainbat faktoreren arabera alda daiteke, horrek GGKaren diagnostikoa arriskuan jar dezake, bereziki gaixotasunaren fase goiztiarrenetan. Haurretan GGKak, arazo metaboliko kardiobaskularrez gain, garapen-arazoak malnutrizioa eragiten ditu. Haur osasuntsuekin...