Virginia Sáez‐Martínez

ORCID: 0000-0003-4061-3410
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About
Contact & Profiles
Research Areas
  • Hydrogels: synthesis, properties, applications
  • Ocular Surface and Contact Lens
  • Electrospun Nanofibers in Biomedical Applications
  • Advanced Drug Delivery Systems
  • Corneal Surgery and Treatments
  • 3D Printing in Biomedical Research
  • Polymer Surface Interaction Studies
  • Surfactants and Colloidal Systems
  • Wound Healing and Treatments
  • Bone Tissue Engineering Materials
  • Nanoparticle-Based Drug Delivery
  • Environmental Toxicology and Ecotoxicology
  • Advanced Polymer Synthesis and Characterization
  • Corneal surgery and disorders
  • Advancements in Transdermal Drug Delivery
  • Proteoglycans and glycosaminoglycans research
  • Marine Biology and Environmental Chemistry
  • Lipid Membrane Structure and Behavior
  • Mollusks and Parasites Studies
  • Polydiacetylene-based materials and applications
  • Protein Interaction Studies and Fluorescence Analysis
  • Dental materials and restorations
  • Graphene and Nanomaterials Applications
  • Silk-based biomaterials and applications
  • Supramolecular Self-Assembly in Materials

CIC energiGUNE
2021-2024

University of Bucharest
2022

Carol Davila University of Medicine and Pharmacy
2022

University of Agronomic Sciences and Veterinary Medicine of Bucharest
2022

Aston University
2015-2020

Smith College
2019

Syracuse University
2019

University of Memphis
2019

Texas A&M University
2019

John Wiley & Sons (United States)
2019

Biomedical devices have become essential in the health care. Every day, an enormous number of these are used or implanted humans. In this context, bacterial contamination that could be developed is critical since it estimated infections kill more people than other medical causes. Commonly, treated with antibiotics, but biofilm formation on implant surfaces significantly reduce effectiveness antibiotics bacteria inside protected from drug. some cases, a complete removal necessary order to...

10.3390/coatings10020139 article EN Coatings 2020-02-04

Hyaluronic acid (HA) injectable biomaterials are currently applied in numerous biomedical areas, beyond their use as dermal fillers. However, bacterial infections and painful inflammations associated with healthcare complications that can appear after injection, restricting applicability. Fortunately, HA hydrogels also serve drug delivery platforms for the controlled release of bioactive agents a critical role control certain diseases. Accordingly, herein, were crosslinked 1 4-butanediol...

10.3390/gels8040223 article EN cc-by Gels 2022-04-06

Traditional wound dressings have not been able to satisfy the needs of regenerative medicine biomedical area. With aim improving tissue regeneration, nanofiber-based fabricated by electrospinning (ES) processes emerged as a powerful approach. Nowadays, bioactive are mainly developed with combination natural and synthetic polymers, such polycaprolactone (PCL) chitosan (CHI). Accordingly, herein, PCL/CHI nanofibers varying PCL:CHI weight ratios (9:1, 8:2 7:3) or CHI viscosities (20, 100 600...

10.3390/polym16101333 article EN Polymers 2024-05-09

Stable hyaluronic acid nanogels were obtained following the water-in-oil microemulsion method by covalent crosslinking with three biocompatible agents: Divinyl sulfone, 1,4-butanediol diglycidyl ether (BDDE), and poly(ethylene glycol) bis(amine). All nanoparticles showed a pH-sensitive swelling behavior, according to pKa value of acid, as consequence ionization carboxylic moieties, it was corroborated zeta potential measurements. QELS studies carried out study influence chemical structure...

10.3390/polym11040742 article EN Polymers 2019-04-24

Granular polymer hydrogels based on dynamic covalent bonds are attracting a great deal of interest for the design injectable biomaterials. Such materials generally exhibit shear-thinning behavior and properties self-healing/recovery after extrusion that can be modulated through interactions between gel microparticles. Herein, bulk macro-hydrogels thiolated-hyaluronic acid were produced by disulphide bond formation using oxygen as oxidant at physiological conditions gelation kinetics...

10.3390/polym15040966 article EN Polymers 2023-02-15

Food consumption and growth variations related to several dosages of heavy metals (Cu, Zn, Hg Pb) in diet were studied the terrestrial slug Arion ater for 27 days experimental treatment. The work reported here is part a larger project investigate histological effects metal exposure pulmonate gastropods. Graphics on food vs. time each metal, regression behaviour observed are presented.

10.1093/mollus/52.1.68 article EN Journal of Molluscan Studies 1986-05-01

Hydrogel materials offer many advantages for chemical and biological sensoring due to their response a small change in environment with related volume. Several designs have been outlined the literature specific field of hydrogel-based optical sensors, reporting large number steps fabrication. In this work we present three-dimensional, sensor structure which is fabricated single step using thermal nanoimprint lithography. The based on waveguide grating readout section. A hydrogel formulation,...

10.3390/s18103240 article EN cc-by Sensors 2018-09-26

Abstract Colloidal nanosized folate‐conjugated hydrogels for targeted chemotherapy were prepared via a versatile and efficient postsynthetic modification pathway starting from P(NPA ‐co‐ NIPAM). The modifications included the introduction of 4‐methylpyridine as pH‐sensitive pendant groups conjugation folic acid to microgel network. microgels showed specific swelling at pH < 6 (endosomes) judged by DLS studies varying external pH. relative composition shows clear influence on volume...

10.1002/macp.200800496 article EN Macromolecular Chemistry and Physics 2009-02-18
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