A5051672577- Environmental Toxicology and Ecotoxicology
- Heparin-Induced Thrombocytopenia and Thrombosis
- Mercury impact and mitigation studies
- Reproductive biology and impacts on aquatic species
- Intramuscular injections and effects
- Platelet Disorders and Treatments
- Selenium in Biological Systems
- Cancer, Hypoxia, and Metabolism
- TGF-β signaling in diseases
- Fish Ecology and Management Studies
- Weed Control and Herbicide Applications
- Antibiotics Pharmacokinetics and Efficacy
- Heme Oxygenase-1 and Carbon Monoxide
- Petroleum Processing and Analysis
- Pharmaceutical studies and practices
- Renal and related cancers
- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Antibiotic Use and Resistance
- Genetics, Aging, and Longevity in Model Organisms
- Aquaculture Nutrition and Growth
- Parathyroid Disorders and Treatments
- Dye analysis and toxicity
- CRISPR and Genetic Engineering
- Toxic Organic Pollutants Impact
- Enhanced Oil Recovery Techniques
McMaster University
2009-2025
Hamilton General Hospital
2025
Hamilton Health Sciences
2021-2025
Mississippi State University
2024
University of Saskatchewan
2012-2020
Mental Health Commission
2017
Patients with end-stage kidney disease on peritoneal dialysis often develop progressive scarring of the tissues. This manifests as submesothelial thickening and is associated increased vascularization that leads to ultrafiltration dysfunction. Hypoxia induces a characteristic series responses including angiogenesis fibrosis. We investigated role hypoxia in membrane damage. An adenovirus expressing transforming growth factor (TGF) β was used induce evaluated effect mTOR inhibitor rapamycin,...
Sensitivity of white sturgeon (Acipenser transmontanus) to copper (Cu) or cadmium (Cd) has been shown significantly differ as a function life-stage. This study investigated oxidative stress, metal homeostasis, and associated compensatory responses potential mechanisms this sensitivity pattern in three early life-stages. Sturgeon were most sensitive Cu at 15 days post hatch (dph), which was accompanied by significant increase lipid peroxidation (LPO). Genes involved with amelioration stress...
Thrombocytopenia and thrombosis have been reported following vaccination with the ChAdOx1 nCoV-19 (AstraZeneca) vaccine, an adenoviral vector COVID-19 (coronavirus disease 2019) vaccine.[1] [2] [3] [4] [5] Previous cases of vaccine-induced immune thrombotic thrombocytopenia (VITT) symptom onset between 5 to 30 days postvaccination, typically severe thrombocytopenia, unusual thromboses, high mortality, platelet-activating antibodies against platelet factor 4 (PF4) despite no previous exposure...
It has been shown that selenium (Se) released to the aquatic environment can have devastating effects on local wildlife. White sturgeon (Acipenser transmontanus) a life history particularly susceptible contaminants, and their protection is of interest as they are culturally economically important, many populations classified endangered. During present 72-d dietary study, multiple signs decreased health Se lethality were observed. Juvenile white given diets containing 1.4 μg, 5.6 22.4 or...
Pulse oximetry (SpO2 ) is a widely used, non-invasive method of estimating arterial oxygen saturation. Measurement SpO2 relies on comparing the relative absorption light in red and infrared regions with expected pattern oxygenated deoxygenation adult hemoglobin. As this screening tool has entered common clinical use, test limitations have emerged, including concern about risk overestimation saturation by pulse disproportionate number people dark skin pigment, leading to potential for...
Introduction: Gentamicin is an aminoglycoside antibiotic with broad-spectrum bactericidal activity and widely used in pediatric units to treat infection susceptible organisms. This study aimed describe the dosage regimen for gentamicin approach its therapeutic drug monitoring (TDM) among within state of New South Wales (NSW). Methods: A questionnaire was sent electronically representatives 40 NSW, requesting details each unit’s dosing TDM policy. Results: total 35 responded survey. The...