A5101787374- Epigenetics and DNA Methylation
- Retinal Development and Disorders
- Pluripotent Stem Cells Research
- CRISPR and Genetic Engineering
- Drug-Induced Ocular Toxicity
- Diverse Approaches in Healthcare and Education Studies
- Genomics and Chromatin Dynamics
- Psychosocial Factors Impacting Youth
- Dementia and Cognitive Impairment Research
- Pregnancy and Medication Impact
- Health and Wellbeing Research
- Health, Environment, Cognitive Aging
- Receptor Mechanisms and Signaling
- Ocular Oncology and Treatments
- Cancer-related gene regulation
- Nicotinic Acetylcholine Receptors Study
- Cancer-related molecular mechanisms research
- Vitamin D Research Studies
- RNA modifications and cancer
- Retinal Diseases and Treatments
- Neuroscience and Neuropharmacology Research
- RNA Research and Splicing
- Pharmacological Effects and Toxicity Studies
Northwest University
2021-2024
Shandong University
2021
Ministry of Education of the People's Republic of China
2021
Janssen (United States)
2018
Daqing Oilfield General Hospital
2017
University of Georgia
2016
Janssen (Belgium)
2012
Institute on Aging
2011
National Institute on Aging
2011
Polysialic acid (PSA) is a carbohydrate polymer of repeating α-2,8 sialic residues that decorates multiple targets, including neural cell adhesion molecule (NCAM). PST and STX encode the two enzymes responsible for PSA modification target proteins in mammalian cells, but despite widespread polysialylation embryonic development, majority studies have focused strictly on role neurogenesis. Using human pluripotent stem cells (hPSCs), we revisited developmental show early progenitors three germ...
To investigate the mechanism of paclitaxel (PTX)-induced macular edema and therapeutic effect carbonic anhydrase inhibitors (CAI) on this condition. The PTX cell morphology was detected by immunofluorescence. Cell barrier measured measuring resistance across epithelium. Western blotting analysis reverse transcription-quantitative polymerase chain reaction (RT-qPCR) were performed to effects or + CAI expression XIV (CAXIV), aquaporin 4 (AQP4) inflammatory factors. After intraperitoneal...
Golden snub-nosed monkey (Rhinopithecus roxellana) is an endangered primate species, whose molecular material for conservation purposes has not yet been maintained. Although small-molecule compounds (SMCs) have reported to improve induced pluripotent stem cells (iPSCs), their efficiency in the interspecies-transferred nucleus still unknown.We thus used fibroblasts from golden treated with SMC as donor cells, injected into enucleated oocytes of goats, test such efficiency. Gene expression...
GWAS is a powerful approach in identifying genetic risk loci. However, the functional elucidation on how locus related to disease still requires much genomics follow up. Further, may have pleiotropic effects. 13 candidate variants implicated Alzheimer's Disease (AD) and/or frontotemporal dementia (FTD) were examined closely using two complementary approaches: phenome-wide association studies (PheWAS) database of 23andMe research participants examine effects variants; and an epigenetic...