A5080502201- Algal biology and biofuel production
- Aquatic Ecosystems and Phytoplankton Dynamics
- Microbial Community Ecology and Physiology
- Biocrusts and Microbial Ecology
- HIV Research and Treatment
- Marine Sponges and Natural Products
- Microbial Natural Products and Biosynthesis
- Bacteriophages and microbial interactions
- Genomics and Phylogenetic Studies
- ZnO doping and properties
- Electronic and Structural Properties of Oxides
- Coastal and Marine Management
- vaccines and immunoinformatics approaches
- Marine and coastal ecosystems
- Fish biology, ecology, and behavior
- Immunotherapy and Immune Responses
- Malaria Research and Control
- HIV/AIDS Research and Interventions
- Copper-based nanomaterials and applications
- Mosquito-borne diseases and control
- Marine Toxins and Detection Methods
- Innovative Human-Technology Interaction
- Monoclonal and Polyclonal Antibodies Research
- HIV/AIDS drug development and treatment
- Aquatic Ecosystems and Biodiversity
Delft University of Technology
2022-2024
Universidade do Porto
2009-2021
University of Minho
2019-2021
Summit (United Kingdom)
2020
Centro Interdisciplinar de Investigação Marinha e Ambiental
2009-2018
Research Center for Natural Resources, Environment and Society
2018
UNSW Sydney
2012
University of Aveiro
2009-2010
Orange (France)
1998
Microbes offer designers opportunities to endow artefacts with environmental sensing and adapting abilities, unique expressions. However, microbe-embedded present a challenge of temporal dissonance, reflected by "time lag" typically experienced humans in noticing the gradual minute shifts microbial metabolism. This could compromise fluency interactions may hinder timely attending microbes living artefacts. In addressing this challenge, we introduce Cyano-chromic Interface, which...
Cyanobacteria are a well-known source of bioproducts which renders culturable strains valuable resource for biotechnology purposes. We describe here the establishment cyanobacterial culture collection (CC) and present first version strain catalog its online database (http://lege.ciimar.up.pt/). The LEGE CC holds 386 strains, mainly collected in coastal (48%), estuarine (11%), fresh (34%) water bodies, most part from Portugal (84%). By following recent taxonomic classification, were...
Microbial mats are complex, micro-scale ecosystems that can be found in a wide range of environments. In the top layer photosynthetic from hypersaline environments, large diversity cyanobacteria typically predominates. With aim strengthening knowledge on cyanobacterial present coastal lagoon system Araruama (state Rio de Janeiro, Brazil), we have characterized three mat samples by means polyphasic approach. We used morphological and molecular data obtained culture-dependent -independent...
Cyanobactins are a family of linear and cyclic peptides produced through the post-translational modification short precursor peptides. A mass spectrometry-based screening potential cyanobactin producers led to discovery new prenylated member this compounds, sphaerocyclamide (1), from Sphaerospermopsis sp. LEGE 00249. The biosynthetic gene cluster (sph) encoding novel macrocyclic cyanobactin, was sequenced. Heterologous expression sph in Escherichia coli confirmed connection between genomic...
Fifty-one cyanobacteria strains, belonging to Phormidium autumnale, Planktothrix mougeotii, Limnotrix sp. and Synechocystis species, were isolated during a twelve months period, from Wastewater Treatment Plant (WWTP) located in the north of Portugal. Isolated strains environmental samples analyzed by Polymerase Chain Reaction (PCR) technique evaluate presence genes linked biosynthesis cyanotoxins, microcystin (MC), nodularin (NOD) cylindrospermopsin (CYN). Even though none contained...
HCI designers increasingly engage in the integration of microbes into artefacts, leveraging their distinct biological affordances for novel interactions. While many explorations interaction between humans and is mediated, scholars also highlight potential direct interactions, such as visualising mechanical distortions or fostering a sense relationality with nonhumans through eliciting intimate encounters. Seizing upon this potential, our study delves realm interactions involving...
Cyanobactins are a recently recognized group of ribosomal cyclic peptides produced by cyanobacteria, which have been studied because their interesting biological activities. Here, we used PCR-based approach to detect the N-terminal protease (A) gene from cyanobactin synthetase clusters, in set diverse cyanobacteria our culture collection (Laboratory Ecotoxicology, Genomics and Evolution (LEGE) CC). Homologues this were found Microcystis Rivularia strains, for first time Cuspidothrix,...
The Nagoya Protocol on Access to Genetic Resources and Fair Equitable Sharing of Benefits Arising from their Utilization came into force in October 2014. In the European Union (EU), new legislation had be developed order apply mandatory elements Protocol, namely, Regulation (EU) Nº 511/2014 (ABS Regulation) Implementing 2015/1866, laying down detailed rules for implementation ABS with regard register collection, monitor user compliance, best practices. As a consequence, EU countries develop...
The extensive genetic diversity of HIV-1 is a major challenge for the prevention and treatment infections. Subtype C accounts most infections in world but has been mainly localized Southern Africa, Ethiopia India. For elusive reasons, South Brazil harbors largest subtype epidemic American continent that elsewhere dominated by B. To investigate this topic, we collected clinical data viral sequences from 2611 treatment-naïve patients diagnosed with Brazil. Molecular epidemiology analysis...
The success of antiretroviral treatment (ART) is threatened by the emergence drug resistance mutations (DRM). Since Brazil presents largest number people living with HIV (PLWH) in South America we aimed at understanding dynamics DRM this country. We analyzed a total 20,226 HIV-1 sequences collected from PLWH undergoing ART between 2008–2017. Results show mild decline over years but an increase K65R reverse transcriptase mutation 2.23% to 12.11%. This gradually occurred following alterations...
Abstract We report on the magnetic and structural properties of two types nanostructures doped with Co or Mn, namely, ZnO nanowires colloidal nanocrystals. Electron paramagnetic resonance (EPR) spectra have been measured analysed to extract information incorporation ions in lattice. A detailed analysis by means simulations experimental EPR confirms that transition metal (TM) were mainly incorporated as TM 2+ , occupying Zn sites wurtzite structure ZnO. Furthermore, for both nanostructures,...
Background Timor-Leste changed its malaria treatment protocol in 2007, replacing the first-line for falciparum from sulphadoxine-pyrimethamine to artemether-lumefantrine. This study explored factors affecting implementation of revised protocol, with an emphasis on identifying key constraints.
Abstract Human immunodeficiency virus 1 (HIV-1) genome sequencing is routinely done for drug resistance monitoring in hospitals worldwide. Subtyping these extensive datasets of HIV-1 sequences a critical first step molecular epidemiology and evolution studies. The clinical relevance subtypes increasingly recognized. Several studies suggest subtype-related differences disease progression, transmission route efficiency, immune evasion, even therapeutic outcomes. subtyping mainly using...
We studied the angular dependence of ferromagnetic resonance (FMR) spectra (0001)ZnO single crystals implanted with Ni and Fe ions compared results to data obtained by other experimental techniques, especially, x-ray diffraction (XRD) superconducting quantum interference device magnetometry. The FMR revealed formation metal nanocrystals (NCs) embedded in ZnO lattice an oriented way. Whereas case Ni, conclusions drawn from studies corroborated XRD magnetometry respect alignment NCs host...
ABSTRACT The use of bacterial transposon mutant libraries in phenotypic screens is a well-established technique for determining which genes are essential or advantageous growth conditions interest. Standard, inactivating, cannot give direct information about whose over-expression gives selective advantage. We report the development system wherein outward-oriented promoters included mini-transposons, generation Escherichia coli and Pseudomonas aeruginosa their to probe important under...
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