- Phytochemical Studies and Bioactivities
- Phytochemistry and Bioactive Compounds
- Natural product bioactivities and synthesis
- Phytochemistry and Biological Activities
- Heat shock proteins research
- Tannin, Tannase and Anticancer Activities
- Liver physiology and pathology
- Phytochemicals and Antioxidant Activities
- Plant-based Medicinal Research
- Congenital heart defects research
- Effects of Radiation Exposure
- Curcumin's Biomedical Applications
- Peptidase Inhibition and Analysis
- Membrane Separation Technologies
- Cell death mechanisms and regulation
- Plant-derived Lignans Synthesis and Bioactivity
- Free Radicals and Antioxidants
- NF-κB Signaling Pathways
- Flavonoids in Medical Research
- Metabolomics and Mass Spectrometry Studies
- Retinoids in leukemia and cellular processes
- Phytochemistry and biological activities of Ficus species
- Ubiquitin and proteasome pathways
- Sirtuins and Resveratrol in Medicine
- RNA Interference and Gene Delivery
Shaanxi University of Chinese Medicine
2015-2024
National University of Singapore
2023
Singapore Institute of Manufacturing Technology
2021
Nanyang Technological University
2021
Wuhan University
2015-2020
Renmin Hospital of Wuhan University
2015-2020
Nanjing Normal University
2013-2014
Guangxi University
2010
China Medical University
2008
Panzhihua Central Hospital
2004
Two new furostanol saponins 1–2 and a spirostanol saponin 3 were isolated together with two known 4–5 from the roots rhizomes of Tupistra chinensis. Their structures characterized as 1β,2β,3β,4β,5β,26-hexahydroxyfurost-20(22), 25(27)-dien-5,26-O-β-d-glucopyranoside (1), 1β,2β,3β,4β,5β,6β,7α,23ξ,26-nona-hydroxyfurost- 20(22),25(27)-dien-26-O-β-d-glucopyranoside (2), (20S,22R)-spirost-25 (27)-en-1β,3β,5β- trihydroxy-1-O-β-d-xyloside (3), tupisteroide B (4)...
Deglucose chikusetsusaponin IVa (DCIVa), isolated from Rhizoma Panacis Majoris, a widely used traditional Chinese medicine, is type of oleanane triterpenoids. Various previous studies have demonstrated that triterpenoids exhibit cytotoxic activity against various types cancer cells. However, whether DCIVa exerts an antitumor effect remains to be elucidated. The present study aimed assess the on cells using HepG2 hepatocellular carcinoma cell line and determine underlying mechanism. Using MTT...
Skin cancers are by far the most common human malignancies. Retinoids have shown promising preventive and therapeutic effects against a variety of The aim this study was to investigate apoptosis-inducing effect acitretin on skin squamous cell carcinoma (SCC) SCL-1 cells. We found that preferentially inhibited growth cells in dose- time-dependent manner, but not non-malignant keratinocyte HaCaT This inhibition appeared be due induction apoptosis as revealed enzyme-linked immunosorbent assay....
The structures of two new cycloartane-type saponin constituents the roots Cimicifuga foetida were established by interpretation spectroscopic data as 2'-O-acetylactein (1) and 2'-O-acetyl-27-deoxyactein (2), respectively. Also isolated known compounds actein, 27-deoxyactein, cimicifugoside H-1, 15alpha-hydroxycimicidol 3-O-beta-D-xyloside.