A5101840879- Fungal and yeast genetics research
- Parkinson's Disease Mechanisms and Treatments
- Pharmacological Effects of Natural Compounds
- Mitochondrial Function and Pathology
- Animal Genetics and Reproduction
- CRISPR and Genetic Engineering
- Gut microbiota and health
- Mycobacterium research and diagnosis
- Wireless Networks and Protocols
- Ubiquitin and proteasome pathways
- Metabolomics and Mass Spectrometry Studies
- Plant Gene Expression Analysis
- Biofuel production and bioconversion
- Nutritional Studies and Diet
- Genetics, Aging, and Longevity in Model Organisms
- Wireless Signal Modulation Classification
- Internet Traffic Analysis and Secure E-voting
- Cancer-related molecular mechanisms research
- Marine Sponges and Natural Products
- Nutrition, Genetics, and Disease
- RNA Interference and Gene Delivery
- Microbial Metabolic Engineering and Bioproduction
- Speech and Audio Processing
- Peptidase Inhibition and Analysis
- Histone Deacetylase Inhibitors Research
South China University of Technology
2025
Institute of Oceanology
2025
University of Chinese Academy of Sciences
2025
University of Cambridge
2023-2025
Fourth Affiliated Hospital of China Medical University
2024
Shandong Normal University
2024
China Medical University
2024
Hubei Academy of Agricultural Sciences
2023
Zhejiang Gongshang University
2023
Deubiquitination, a post-translational modification regulated by deubiquitinases, is essential for cancer initiation and progression. Ubiquitin-specific proteases (USPs) are elements of the deubiquitinase family, overexpressed in gastric (GC). Through regulation several signaling pathways, such as Wnt/β-Catenin nuclear factor-κB signaling, promotion expression deubiquitination- stabilization-associated proteins, USPs promote proliferation, metastasis, invasion, epithelial-mesenchymal...
Gastric cancer (GC) ranks as the third most prevalent malignancy and a leading cause of cancer-related mortality worldwide. However, majority patients with GC are diagnosed at an advanced stage, highlighting urgent need for effective perioperative postoperative chemotherapy to prevent relapse metastasis. The current treatment strategies have limited overall efficacy because intrinsic or acquired drug resistance. Recent evidence suggests that dysregulated long non-coding RNAs (lncRNAs) play...
ABSTRACT Agaricus blazei Murill polysaccharide (ABMP) has been found to exhibit significant immune regulatory effects, making them a promising candidate for complementary the pharmacological treatment of colorectal cancer immune‐related diseases. As prevalence among younger individuals increases, possible age‐dependent anticancer modulatory effect ABMP not clarified. This study evaluated immunoregulatory efficacy polysaccharides extraction from A. in colon tumor. Hematoxylin‐eosin staining,...
The cell wall integrity (CWI) pathway is responsible for transcriptional regulation of remodeling in response to stress. How mediated by the CWI effected inputs from other signaling pathways not well understood. Here, we demonstrate that Mck1 kinase cooperates with Slt2, MAP pathway, promote thickening glucose-starved cells. Integrative analyses transcriptome, proteome and metabolic profiling indicate required accumulation UDP-glucose (UDPG), substrate β-glucan synthesis, through activation...
Ageing is a universal decline of physiological functions accompanied by an increase in risks developing morbidity, diseases, and death. Calorie restriction (CR) without malnutrition has been shown to improve lifespan from simple model organisms mammals, extensive research over the past decades have identified several universally conserved signalling pathways which CR regulates lifespan. More recently, emerging evidence suggested that modulation intake levels macronutrients micronutrients can...
Compared to replicative lifespan, epigenetic regulation of chronological lifespan (CLS) is less well understood in yeast. Here, by screening all the viable mutants histone acetyltransferase (HAT) and deacetylase (HDAC), we demonstrate that Gcn5, functioning HAT module SAGA/SLIK complex, exhibits an epistatic relationship with HDAC Hda1 control expression starvation-induced stress response respiratory cell growth. Surprisingly, gcn5Î lose their colony-forming potential early stationary phase...
Wireless traffic prediction is essential to developing intelligent communication networks that facilitate efficient resource allocation. Along this line, decentralized wireless under the paradigm of federated learning becoming increasingly significant. Compared traditional centralized learning, satisfies network operators’ requirements for sensitive data protection and reduces consumption resources. In paper, we propose a novel communication-efficient framework, named FedCE, by gradient...