A5100329454- Spine and Intervertebral Disc Pathology
- Musculoskeletal pain and rehabilitation
- Spinal Fractures and Fixation Techniques
- Phytochemicals and Antioxidant Activities
- Autoimmune Bullous Skin Diseases
- Coagulation, Bradykinin, Polyphosphates, and Angioedema
- Urticaria and Related Conditions
- Fungal Biology and Applications
- Trigeminal Neuralgia and Treatments
- Pelvic and Acetabular Injuries
- Pain Management and Treatment
- Reproductive Biology and Fertility
- Cervical and Thoracic Myelopathy
- Advanced Chemical Sensor Technologies
- Free Radicals and Antioxidants
- Cancer Mechanisms and Therapy
- Sexual function and dysfunction studies
- Electrochemical sensors and biosensors
- Neurological Disease Mechanisms and Treatments
- Electrochemical Analysis and Applications
- Ferroptosis and cancer prognosis
- Plant Pathogens and Fungal Diseases
- Intracranial Aneurysms: Treatment and Complications
- Acute Ischemic Stroke Management
- Spinal Cord Injury Research
Xinjiang Medical University
2017-2023
Dongguan University of Technology
2023
Zhejiang Gongshang University
2023
First Affiliated Hospital of Xinjiang Medical University
2017-2023
The First Affiliated Hospital, Sun Yat-sen University
2023
Zhongshan Hospital
2023
Fudan University
2022-2023
Sun Yat-sen University
2023
Wenzhou Medical University
2015-2022
Tsinghua University
2022
Abstract Intervertebral disc (IVD) degeneration is closely associated with low back pain (LBP), which a major health concern in the U.S. Cellular biosynthesis of extracellular matrix (ECM), important for maintaining tissue integrity and preventing degeneration, an energy demanding process. Due to impaired nutrient support avascular IVD, adenosine triphosphate (ATP) supply could be limiting factor normal ECM synthesis. Therefore, objective this study was investigate metabolism annulus...
Spinal cord injury (SCI) causes severe neural tissue damage and motor/sensory dysfunction. Since the injured spinal has limited self-regeneration ability, several strategies, including cell therapy, drug delivery, engineering scaffold implantation, have been employed to treat SCI. However, each of these strategies fails obtain desirable outcomes due their respective limitations. In comparison, advanced scaffolds with appropriate topographical features, favorable composition, sustained...
To observe the efficacy and toxicity of autologous hematopoietic stem cell transplantation (HSCT) in progressive multiple sclerosis (PMS).Twenty-one patients with PMS were treated HSCT. Stem cells mobilized cyclophosphamide (CY) granulocyte colony-stimulating factor. After conditioning regimen CY total body irradiation or BEAM, reinfused. CD34+ selection graft was performed anti-thymocyte globulin given for T-cell depletion. The probabilities confirmed progression-free survival disease...
The aim of the present study was to retrospectively evaluate progressive correction coronal and sagittal alignment pelvic parameters in patients treated with a Chêneau brace.Thirty-two adolescent idiopathic scoliosis (AIS) were assessed before initiation bracing treatment at final follow-up. Each patient underwent radiological examinations, coronal, sagittal, measured.No statistically significant modification Cobb angle noted. incidence remained unchanged 59% cases increased 28% cases....
Objective The purpose of this study was to investigate the clinical efficacy unilateral biportal endoscopic transforaminal lumbar interbody fusion (UBE-TLIF) for spinal stenosis (LSS). Methods Patients who underwent UBE-TLIF due single-segment LSS between August 2019 and July 2021 were retrospectively included in study. Clinical outcomes evaluated include operative time, estimated blood loss (including postoperative drainage), time ambulation, hospital stay, complications, visual analog...
The objectives of this investigation were to evaluate the serum 25-hydroxyvitamin D [25(OH)D] concentrations in pigs different age groups, determine if 25(OH)D varied with season, and assess quality vitamin supplements used swine diets from multiple commercial suppliers. Serum samples (n = 1200) submitted a diagnostic laboratory for routine surveillance assayed concentrations. Vitamin premix obtained suppliers analyzed at two laboratories over 9-month period. In all categories, numerous...
The objective of this study was to investigate the treatment and prognosis patients with spinal tuberculosis in Guizhou province. A total 863 admitted our hospital from 2006 2017 were included study. All underwent standardized quadruple antituberculosis treatment. Eighty lost follow-up due a change their contact information or noncompliance. 783 completed follow-up. average period 20.33 ± 8.77 months (range: 6 38 months). Among these patients, 145 conservative treatment, while 638 surgical...
Ageing is a universal decline of physiological functions accompanied by an increase in risks developing morbidity, diseases, and death. Calorie restriction (CR) without malnutrition has been shown to improve lifespan from simple model organisms mammals, extensive research over the past decades have identified several universally conserved signalling pathways which CR regulates lifespan. More recently, emerging evidence suggested that modulation intake levels macronutrients micronutrients can...
Spinal hydatid disease is rare and remains a serious health problem associated with high rates of recurrence. We report our experience in treating patients thoracic spinal hydatidosis through single-center case-series study.Sixteen were treated center between 1995 2017. A total en bloc spondylectomy (TES) was performed three patients. Five posterior decompression stabilization after removing the involved elements. The remaining underwent curettage resection infected bone. therapy completed...
A 71-year-old woman had presented to our clinic with the history of trigeminal neuralgia involving second and third divisions on right side. The magnetic resonance tomography angiography examination before operation revealed that root nerve was compressed by superior cerebellar artery (SCA) artery. During operation, a fusiform aneurysm visualized at distal portion SCA. symptoms pain disappeared after surgery microvascular decompression wrapping SCA aneurysm. Trigeminal coexisting ipsilateral...
Changes in body composition are related to mobility, fall risk, and mortality, especially older adults. Various devices methods exist measure composition, but bioelectrical impedance analysis (BIA) has several advantages. The purpose of this study was validate a common BIA device with dual-energy X-ray absorptiometer (DXA) adults develop prediction equations improve the accuracy measurements. participants were 277 (162 women 115 men; age 73.9 ± 5.8 years) without history cancer severe...
Abstract: Epidermolysis bullosa acquisita (EBA) is a rare, acquired, subepidermal blistering disease characterized by autoantibodies directed against type VII collagen, the major component of anchoring fibrils. We report 5‐year‐old Chinese boy who presented with extensive lesions consisting disseminated pruritic vesicles and tense blisters. The diagnosis EBA was confirmed histopathology, immunofluorescence, immunoblotting analysis. controlled combination prednisone dapsone.
Previous reports have shown that indirect immunofluorescence (IIF) performed on sodium chloride-split skin (SSS) is helpful to differentiate epidermolysis bullosa acquisita (EBA) from bullous pemphigoid (BP). Antibodies of BP may bind the epidermal side SSS, while antibodies EBA dermal side.To determine accuracy IIF-SSS in differential diagnosis and utilizing immunoblotting (IB) analysis.Sera 78 patients, diagnosed with by clinical features, histopathology, direct (DIF), were assayed using...
Background: Bullous pemphigoid (BP) is an acquired autoimmune subepidermal blistering disease characterized by circulating IgG autoantibodies directed against BP180 and BP230 hemidesmosomal proteins.Previous studies have demonstrated that antibodies the NC16a domain of mediate BP pathogenesis, while enhance inflammatory response.Recently, commercial BP180-NC16a enzymelinked immunosorbent assay (ELISA) ELISA kits were developed to detect anti-BP180 anti-BP230 in human sera.Aims: To evaluate...
A 22-year-old primigravida had a pruritic, erythematous, bullous eruption on the skin during 26th week of gestation. After delivery flared up. The diagnosis pemphigoid gestationis was confirmed based histopathological and immunofluorescence findings. result immunoblotting showed IgG autoantibodies which reacted against BP230 in epidermal extracts 290 kDa type VII collagen dermal extracts. BP180 antibodies were also detected by an enzyme-linked immunosorbent assay BP180NC16a kit. Pulsed...
Abstract Objective This study was aimed to investigate the effects of microvascular decompression (MVD) on sleep disorders and obsessions in trigeminal neuralgia. Methods Clinical data from 115 patients with neuralgia treated MVD August 1, 2017 May 31, 2018 at Jining First People's Hospital were analyzed retrospectively. The preoperative postoperative risk factors for obsessions, as well examined. Results In patients, there significant differences associated sex, monthly household income,...
To investigate the application of intelligent puncture blood collection robots in anticoagulated specimens, satisfaction subjects with two methods, and feasibility devices to replace manual methods clinical work.A total 154 volunteers from Zhongshan Hospital Fudan University were recruited compare test results anticoagulant samples between robot collection, a questionnaire was used inquire about volunteers' feelings methods; data 6,255 patients willing use for collected analyze success rate...