A5081721358- Genetic and Clinical Aspects of Sex Determination and Chromosomal Abnormalities
- Sexual Differentiation and Disorders
- Sperm and Testicular Function
- Prenatal Screening and Diagnostics
- Genomic variations and chromosomal abnormalities
- Reproductive Biology and Fertility
- Chromosomal and Genetic Variations
- Genetics and Neurodevelopmental Disorders
- Chronic Myeloid Leukemia Treatments
- Gut microbiota and health
- Folate and B Vitamins Research
- Spine and Intervertebral Disc Pathology
- Assisted Reproductive Technology and Twin Pregnancy
- Genetic factors in colorectal cancer
- Acute Lymphoblastic Leukemia research
- Urological Disorders and Treatments
- Galectins and Cancer Biology
- Williams Syndrome Research
- Antiplatelet Therapy and Cardiovascular Diseases
- Protein Tyrosine Phosphatases
- Estrogen and related hormone effects
- CRISPR and Genetic Engineering
- Cardiac electrophysiology and arrhythmias
- Genomics and Rare Diseases
- Blood Coagulation and Thrombosis Mechanisms
University of Sfax
2015-2025
Universidad Autónoma de Baja California
2023
Madurai Medical College
2023
Sols, Solides, Structures, Risques
2016
Centre Hospitalier Universitaire Hassan II
2014
Hôpital Paule de Viguier
2008
Hôpital Farhat Hached
2008
Lille’s Cardiology Hospital
2008
Institut Paoli-Calmettes
2007-2008
Yahoo (Spain)
2004
The coronary artery disease (CAD) is a chronic inflammatory involving genetic as well environmental factors. Recent evidence suggests that the oral microbiome has significant role in triggering atherosclerosis. present study assessed composition variation between patients and healthy subjects order to identify potential pathogenic signature associated with CAD. We performed metagenomic profiling of salivary microbiomes by 16S ribosomal RNA (rRNA) next-generation sequencing. Oral microbiota...
Introduction Noonan-like syndrome with loose anagen hair (NSLH MIM 607721) is associated to mutations in PTPN11, RAF1, BRAF and SHOC2 genes. Objectives Here, we report behavioral phenotype of a child suspected have NSLH. Methods A 2-years-old Tunisian harboring severe pulmonic valvular stenosis was referred our genetic counselling for assessment. Medical dysmorphology, cytogenetic analysis as well exploration RAS-MAPK pathway genes were conducted. Results The had short stature ectodermal...
Progressive multifocal leukoencephalopathy (PML) is a rare demyelinating infection of the central nervous system caused by JC papovavirus usually seen among immunocompromised patients. PML arises upon virus reactivation during periods immunosuppression. may be patients with
Uridine diphosphate-glucuronosyl transferase 1A1 (UGT1A1), which is the major UGT1 gene product, located on chromosome 2q37. The expression of UGT1A1 relatively managed by a polymorphic dinucleotide repeat inside promoter TATA box consisting 5-8 copies TA repeat. A (TA) 6TAA considered as wild type. 7TAA allele has been identified most frequent in Caucasian populations while 8TAA remains rarest worldwide North Africa, including Arab populations.The spectrum genetic mutations seventeen...
We describe a female infant with severe abnormal phenotype de novo partial duplication of the short arm X chromosome. Chromosome painting confirmed origin this duplication. Molecular cytogenetic analysis fluorescence in situ hybridization (FISH) was performed YAC probes, further delineating breakpoints. The karyotype 46, dup(X)(p11‐p21.2).Cytogenetic replication studies showed that normal and duplicated chromosomes were randomly inactivated lymphocytes. In most females structurally...
Introduction While the acoustic environment in cities correlates with various health-related problems, health benefits of natural sounds are proven. These positive effects nature should probably be taken seriously urban design and renewal projects. Objectives The aim this study was to review paradigm soundscapes cities, psychological potential recommendations for such architecture design. Methods We conducted a comprehensive scientific literature using Web databases following keywords:...
Methylenetetrahydrofolate reductase (MTHFR) gene polymorphisms, mainly the C677T, have been implicated as risk factors for several cancers acute lymphoblastic leukemia (ALL). In addition, a potential effect of such variant on efficacy methotrexate (MTX) has reported.In this study, we evaluated impact C677T MTHFR MTX-related toxicity in ALL patients from Tunisia; to provide new insights personalized therapy based human genotype.Genotyping was carried out with restriction fragment length...