A5029802418- Nausea and vomiting management
- Cancer survivorship and care
- Anesthesia and Pain Management
- Sarcoma Diagnosis and Treatment
- Lung Cancer Research Studies
- Cancer Treatment and Pharmacology
- Pharmacological Effects and Toxicity Studies
- Soft tissue tumor case studies
- Childhood Cancer Survivors' Quality of Life
- Cancer therapeutics and mechanisms
- Neuroendocrine Tumor Research Advances
- Cardiac tumors and thrombi
- Palliative Care and End-of-Life Issues
- Lung Cancer Treatments and Mutations
- Pathogenesis and Treatment of Hiccups
- Cancer-related cognitive impairment studies
- Sympathectomy and Hyperhidrosis Treatments
- Lung Cancer Diagnosis and Treatment
- IgG4-Related and Inflammatory Diseases
- Management of metastatic bone disease
- Advanced Radiotherapy Techniques
- Peptidase Inhibition and Analysis
- Soft tissue tumors and treatment
- Fibromyalgia and Chronic Fatigue Syndrome Research
- Psychiatric care and mental health services
Azienda Ospedaliera S.Maria
2012-2024
University of Perugia
2021-2022
Ospedale Santa Maria
2010-2020
Azienda Ospedaliera di Perugia
2006-2018
Santa Maria Nuova Hospital
2012-2018
Ospedale degli Infermi
2007
Azienda Ospedaliera Treviglio
2007
The activity of ginger in the management chemotherapy-induced nausea and vomiting (CINV) has been suggested, but design inadequacies, heterogeneity population, small numbers poor quality tested products limit possibility to offer generalizable results.
•Medical treatment in the advanced setting for retroperitoneal LPS and LMS is scarce.•A subgroup of patients treated with trabectedin, median PFS TTP1 were 6 months 7.5 months, respectively.•GMI was >1.33 52% patients.•A low-grade had a GMI >5, thus suggesting peculiar sensitivity to trabectedin this histotype. BackgroundThis multicentre, single-arm, phase II study aimed at further exploring activity as second-/further-line leiomyosarcoma (LMS) well-differentiated/dedifferentiated...
Solitary fibrous tumors are rare mesenchymal spindle cell neoplasms that usually found in the pleura. The kidneys an uncommon site and only few cases of renal solitary tumor exhibit malignant behavior metastasizing to liver, lung, bone through hematogenous pathway.To describe first case lymph node metastasis from order increase knowledge about these tumors.A 19-year-old female patient had intermittent hematuria for several months without flank pain or other symptoms. A chest abdomen CT scan...
Patients with cancer frequently use dietary supplementation and herbal therapies to control symptoms of disease adverse effects therapy. Despite the widespread in oncology, robust scientific evidence this area is lacking. Not only do these products need be tested large well-designed observational or randomized studies, but their manufacturing process must improved achieve higher levels standardization product quality. Ginger used counteract chemotherapy-induced nausea vomiting (CINV), some...
A concomitant drug-based score was developed by our group and externally validated for prognostic predictive purposes in patients with advanced cancer treated immune checkpoint inhibitors (ICIs). The model considers the use of three classes drugs within a month before initiating ICI, assigning 1 each between proton pump inhibitor antibiotic administration until immunotherapy initiation 2 case corticosteroid intake. In present analysis, drug prospective population 305 metastatic renal cell...
Primary renal extra-skeletal Ewing sarcoma is a rare neoplasm, often metastatic at diagnosis, and with poor outcome. A multimodal approach the treatment of choice in this aggressive neoplasm. We present case primary 45-year-old woman who underwent tumor resection without clear margins. After no response to first cycle chemotherapy, we documented an early onset local recurrence. The patient refused any other died four months after surgery.
Cancer-related fatigue (CRF) is a very common and distressing symptom experienced by most cancer patients, during after treatments also at the end of life. There no accepted definition CRF, because it multifaceted that involves multiple biopsychosocial aspects. Several scales for assessing CRF have been used, unidimensional or multidimensional, but there agreement regarding best instrument to measure CRF. Concerning treatment, pharmacologic non-pharmacologic interventions used. Pharmacologic...
9503 Background: A combination of aprepitant, a 5-HT3 receptor antagonist, and dexamethasone is recommended for the prophylaxis cisplatin-induced nausea vomiting in acute phase, aprepitant+dexamethasone (A+D) delayed phase. Aim this study was to verify if A+D superior metoclopramide plus (M+D) preventing emesis cancer patients receiving same emesis. Methods: randomized double-blind comparing versus M+D completed previously untreated patients. Before chemotherapy, all were treated with...
11575 Background: To further explore the activity of T as second/further line treatment in retroperitoneal leiomyosarcoma (LMS) and well differentiated/dedifferentiated liposarcoma (LPS). The primary endpoint study was growth modulation rate (GMR) defined ratio between time to progression under (TTP) during previous chemotherapy (TTP-1). secondary end-points were objective response per RECIST PFS. Methods: This a multicenter, single-arm Phase 2 study, conducted 20 Italian centers. Patients...
Cancer-related fatigue (CRF) is a very distressing symptom experienced by most cancer patients. CRF complex and there no agreement regarding the exact definition, best measurement instrument or even optimal treatment. an important problem especially in breast patients, during after treatment, long-term survivors. In last few decades survival rates have dramatically improved. Thus, number of survivors has increased preservation quality life become important. This paper literature review...
9614 Background: A combination of AP + a 5-HT3 receptor antagonist D and alone is recommended, respectively, for the prophylaxis acute delayed emesis induced by A+C CT in breast cancer pts. In registrative study role was not defined because different between two arms, superiority on could be consequence dependent effect results achieved phase. Aim this to compare efficacy versus preventing pts receiving same emesis. Methods: randomized double-blind comparing completed naive treated with A+C....