A5040899243- Breast Implant and Reconstruction
- Breast Cancer Treatment Studies
- Reconstructive Surgery and Microvascular Techniques
- Cancer Cells and Metastasis
- Breast Lesions and Carcinomas
- Body Contouring and Surgery
- Mesenchymal stem cell research
- Synthesis and biological activity
- Reconstructive Facial Surgery Techniques
- Cancer, Hypoxia, and Metabolism
- Cancer, Lipids, and Metabolism
- Cancer Diagnosis and Treatment
- Cancer and Skin Lesions
- Bioactive Compounds and Antitumor Agents
- Synthesis of heterocyclic compounds
- Angiogenesis and VEGF in Cancer
- Body Image and Dysmorphia Studies
- Synthesis and Biological Evaluation
- Synthesis and Characterization of Heterocyclic Compounds
- Inflammatory mediators and NSAID effects
- Nonmelanoma Skin Cancer Studies
- Cancer Treatment and Pharmacology
- Head and Neck Cancer Studies
- Gastric Cancer Management and Outcomes
- Surgical site infection prevention
European Institute of Oncology
2011-2021
Breast Center
2010-2020
Geisinger Medical Center
2019
Geisinger Wyoming Valley Medical Center
2019
Ripamonti
2005-2017
Center For Reconstructive Urethral Surgery
2008-2016
Centre Hospitalier Universitaire de Toulouse
2013
Institut Gustave Roussy
1988-2012
Mahidol University
2012
Siriraj Hospital
2012
Lipofilling is now performed to improve the breast contour, after both breast-conserving surgery and reconstruction. However, injection of fat into a previous tumor site may create new environment for cancer adjacent cells. There also no international agreement regarding lipofilling treatment.The authors included three institutions specializing in treatment reconstruction (European Institute Oncology, Milan, Italy; Paris Breast Center, Paris, France; Leon Berard Centre, Lyon, France)...
A clinical trial was conducted at the Institut Gustave Roussy between October 1972 and December 1980 to compare mastectomy with local excision plus Cobalt-irradiation, in patients breast cancer tumors of 20 mm diameter or less macroscopic examination. Low-axillary dissection extemporaneous histologic examination were carried out for all patients. If one more positive nodes found, complete axillary performed. The study included 179 No significant difference detected either overall...
To determine the value of contrast material-enhanced subtraction magnetic resonance (MR) imaging in assessment response to chemotherapy locally advanced breast cancer.Eighteen women treated with because cancer underwent preoperative MR examination including both routine and dynamic sequences after injection gadolinium tetraazacyclododecanetetraacetic acid. Any early enhancement, concomitant vascular enhancement during study, was considered pathologic.Dynamic studies showed all residual tumor...
Abstract Previous studies have suggested a “catalytic role” in neoplastic angiogenesis and cancer progression for bone marrow–derived endothelial progenitor cells (EPC). However, preclinical clinical shown that the quantitative role of marrow-derived EPCs vascularization is extremely variable. We found human murine white adipose tissue (WAT) very rich reservoir CD45-CD34+ with differentiation potential, containing mean 263 times more cells/mL than marrow. Compared CD34+ mobilized blood by...
Obesity is associated with an increased frequency, morbidity, and mortality of several types neoplastic diseases, including postmenopausal breast cancer. We found that human adipose tissue contains two populations progenitors cooperative roles in CD45(-)CD34(+)CD31(+)CD13(-)CCRL2(+) endothelial cells can generate mature capillaries. Their cancer-promoting effect the was limited absence CD45(-)CD34(+)CD31(-)CD13(+)CD140b(+) mesenchymal progenitors/adipose stromal (ASC), which generated...
Nipple sparing mastectomy (NSM) can be performed for prophylactic and the treatment of selected breast cancer with oncologic safety. The risk skin nipple necrosis is a frequent complication NSM procedure, it usually related to surgical technique. However, role morphology should also investigated.We prospectively an analysis 124 from September 2012 January 2013 at European Institute Oncology, Milan, Italy, focusing on necrotic complications. We analyzed association between risks...
Background: Fat grafting has been widely indicated for postmastectomy and postlumpectomy breast reconstruction. The literature emphasizes the clinical efficacy of fat grafting, but experimental studies raise important questions about recurrence risk because stimulation remaining cancer cells by progenitor or adult adipocytes. Because conservative treatment provides a higher residual in tissue compared with mastectomy, authors set up matched case-control study versus no after treatment....
Basal cell carcinoma is the most frequent cutaneous carcinoma, and it characterized by its local spreading an exceptional tendency to metastasize. Radical excision or destruction ensures highest chance of cure. The site this tumor face, where radical limited proximity essential anatomic structures. main difficulty avoid mutilation provide good cosmetic results despite vicinity eyes, nose, mouth. Surgery radiotherapy are known similar chances cure, but concerning sequelae controversial,...
Background Breast cancer surgery has become less and mutilating, however a mastectomy is required in the case of multicentric, large tumors or recurrences after conservative treatment. The removal nipple areola complex during dramatically increases feeling mutilation. To reduce this negative psychological impact, cancers located outside central area breast, we propose new type nipple-sparing associated with intraoperative electron beam radiotherapy (ELIOT) delivered on region areola....
Background. Breast conservation is now established treatment for patients with small breast cancers. The authors reviewed a large series of long term follow-up who underwent conservative treatment. Clinical and pathologic factors were analyzed to identify at an increased risk relapse in the (local relapse) or development contralateral tumor. Methods. Seven hundred fifty-seven unilateral invasive cancer (T0-2, N0-1, M0) treated conservatively (wide local excision radio-therapy) Institut...