André Vessoni Alexandrino

ORCID: 0000-0002-0111-3491
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Research Areas
  • Plant Pathogenic Bacteria Studies
  • Plant-Microbe Interactions and Immunity
  • Legume Nitrogen Fixing Symbiosis
  • Banana Cultivation and Research
  • Polysaccharides and Plant Cell Walls
  • Bioinformatics and Genomic Networks
  • Adipose Tissue and Metabolism
  • Hormonal Regulation and Hypertension
  • Insect Resistance and Genetics
  • Microbial Metabolites in Food Biotechnology
  • Plant nutrient uptake and metabolism
  • Birth, Development, and Health
  • Nanoplatforms for cancer theranostics
  • Mitochondrial Function and Pathology
  • Enzyme Production and Characterization
  • Plant tissue culture and regeneration
  • Click Chemistry and Applications
  • Cancer Research and Treatments
  • Plant pathogens and resistance mechanisms
  • Plant Genetic and Mutation Studies
  • Radiation Therapy and Dosimetry
  • Pregnancy and preeclampsia studies
  • Metal-Catalyzed Oxygenation Mechanisms
  • Protein Structure and Dynamics
  • Cardiovascular and exercise physiology

Universidade Federal de São Carlos
2016-2024

Centro Universitário Central Paulista
2022-2024

Citrus canker, caused by bacteria Xanthomonas citri subsp. citri, can affect all economically important varieties of citrus. Studying genes related to the invasive capacity may improve knowledge on how this works and ultimately use information avoid disease. Some annotated from published genome are addressed an interesting class named "pathogenicity, virulence adaptation". One them is xanA, which encodes a predicted phosphoglucomutase. Phosphoglucomutases ubiquitous enzymes among living...

10.1016/j.bbapap.2016.08.014 article EN publisher-specific-oa Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics 2016-08-30

Citrus canker is a plant disease caused by the bacteria Xanthomonas citri subsp. that affects all domestic varieties of citrus. Some annotated genes from X. genome are assigned to an interesting class named "pathogenicity, virulence and adaptation". Amongst these sodM, which encodes for gene product XcSOD, one four superoxide dismutase homologs predicted genome. SODs widespread enzymes play roles in oxidative stress response, catalyzing degradation deleterious radical. In Xanthomonas, SOD...

10.1371/journal.pone.0209988 article EN cc-by PLoS ONE 2019-01-07

Citrus canker, caused by the bacterium Xanthomonas citri subsp. (Xcc), is a severe disease of citrus. Xcc presents broad spectrum citrus hosts including economically important species whereas X. fuscans aurantifolii–type C (XauC) causes milder and only infects aurantifolia. Trehalase catalyzes hydrolysis disaccharide trehalose, sugar that has been reported to be related pathogenicity. We expressed recombinant gene product assessed trehalase structural kinetics data. The protein presented...

10.1371/journal.pone.0162886 article EN cc-by PLoS ONE 2016-09-09

To investigate whether ovariectomy affects mitochondrial respiratory function, gene expression of the biogenesis markers and dynamics vastus lateralis muscle, female Wistar rats divided into ovariectomized (OVX) intact (INT) groups were kept sedentary (SED) or submitted to resistance training (RT) performed for thirteen weeks on a vertical ladder in which animals climbed with workload apparatus. RT sessions four climbs 65, 85, 95, 100 % rat's previous maximum workload. Mitochondrial...

10.1016/j.exger.2023.112081 article EN cc-by Experimental Gerontology 2023-01-03

Citrus canker, caused by the bacterium Xanthomonas citri (Xcc), is one of most devastating diseases for citrus industry. Xylose a constituent cell wall plants, and ability Xcc to use this carbohydrate may play role in virulence. has two genes codifying xylose isomerase (XI), bifunctional enzyme that interconverts D-xylose into D-xylulose D-glucose D-fructose. The aim work was investigate functional putative XI ORFs, XAC1776 (xylA1) XAC4225 (xylA2), pathogenicity. XI-coding were deleted,...

10.3390/ijms241411491 article EN International Journal of Molecular Sciences 2023-07-15

The causative agent of Asiatic citrus canker, the Gram-negative bacterium Xanthomonas citri subsp. (XAC), produces more severe symptoms and attacks a larger number citric hosts than fuscans aurantifolii XauB XauC, agents cancrosis, milder form disease. Here we report comparative proteomic analysis periplasmic-enriched fractions XAC in XAM-M, pathogenicity- inducing culture medium, for identification differential proteins. Proteins were resolved by two-dimensional electrophoresis combined...

10.1371/journal.pone.0243867 article EN cc-by PLoS ONE 2020-12-18

ABSTRACT Xanthomonas citri subsp. (Xcc) is a bacterium that causes citrus canker, an economically important disease results in premature fruit drop and reduced yield of fresh fruit. In this study, we demonstrated the involvement XanB, enzyme with phosphomannose isomerase (PMI) guanosine diphosphate-mannose pyrophosphorylase (GMP) activities, Xcc pathogenicity. Additionally, found XanB inhibitors protect host against infection. Besides being deficient motility, biofilm production, ultraviolet...

10.1128/spectrum.03673-23 article EN cc-by Microbiology Spectrum 2024-05-09

Menopause occurs due to the depletion of ovarian reserve, leading a progressive decline in estrogen (E2) levels. This decrease E2 levels increases risk developing several diseases and can coexist with chronic kidney disease (CKD). Arterial hypertension (AH) is another condition associated menopause may either contribute or result from CKD. Ovariectomy (OVX) induces hypoestrogenism, which lead mitochondrial bioenergetic dysfunction kidneys. Previous studies have suggested that exercise...

10.3390/ijms26010266 article EN International Journal of Molecular Sciences 2024-12-31

Abstract IL-2 and TRAIL are therapeutic agents known for their antitumor role, but they can be cleared quickly by the body or cytotoxic, compromising function. To reverse this impasse, synthesis of these live bacteria directly in tumor is a viable approach, due to bacteria’s preference colonize tissue. It happens because high nutrient grid microenvironment possible escape from immune system since solid tumors ischemic have regions hypoxia. In context, attenuated Salmonella represents...

10.21203/rs.3.rs-2256306/v1 preprint EN cc-by Research Square (Research Square) 2022-11-14
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