Eran Klein

ORCID: 0000-0002-0132-5777
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About
Contact & Profiles
Research Areas
  • Neuroethics, Human Enhancement, Biomedical Innovations
  • Neurological disorders and treatments
  • EEG and Brain-Computer Interfaces
  • Neuroscience and Neural Engineering
  • Mental Health and Psychiatry
  • Ethics in Clinical Research
  • Cognitive Functions and Memory
  • Biomedical Ethics and Regulation
  • Healthcare Decision-Making and Restraints
  • Ethics in medical practice
  • Patient-Provider Communication in Healthcare
  • Functional Brain Connectivity Studies
  • Autism Spectrum Disorder Research
  • Health Systems, Economic Evaluations, Quality of Life
  • Dementia and Cognitive Impairment Research
  • Palliative Care and End-of-Life Issues
  • Parkinson's Disease Mechanisms and Treatments
  • Artificial Intelligence in Healthcare and Education
  • Obsessive-Compulsive Spectrum Disorders
  • Genetic Neurodegenerative Diseases
  • Psychology of Moral and Emotional Judgment
  • Pharmaceutical industry and healthcare
  • Pharmacovigilance and Adverse Drug Reactions
  • Sleep and related disorders
  • Advanced MRI Techniques and Applications

Oregon Health & Science University
2016-2025

University of Washington
2015-2024

United States University
2024

Stanford University
2024

VA Portland Health Care System
2017-2024

Vanderbilt University Medical Center
2024

Seattle University
2017-2024

University of Portland
2019

Portland VA Medical Center
2013-2019

University of North Carolina at Chapel Hill
2018

To describe the clinical characteristics of encounters with patients misdiagnosed multiple sclerosis (MS).A cross-sectional Internet-based physician survey MS specialists was performed.The response rate for 50.4%. Of those who responded, majority (95%) reported having evaluated 1 or more had been diagnosed MS, but they strongly felt did not have within last year. The respondents (>90%) also use disease-modifying therapy in a proportion these patients. Most (94%) found equally challenging...

10.1212/wnl.0b013e318259e1b2 article EN Neurology 2012-05-12

Patients who have undergone deep brain stimulation (DBS) for emerging indications unique perspectives on ethical challenges that may shape trial design and identify key features BCI-driven DBS systems. research in cognitive emotional disorders has generated significant interest. Much of this work focused developing guidelines recommendations open-loop While early trials depression gave disappointing results, is moving toward clinical with closed-loop or patient-controllable systems modulate...

10.1080/2326263x.2016.1207497 article EN Brain-Computer Interfaces 2016-07-02

In this article, we explore how deep brain stimulation (DBS) devices designed to "close the loop"—to automatically adjust levels based on computational algorithms—may risk taking individual agent "out of loop" control in areas where (at least apparent) conscious is a hallmark our agency. This particular concern area psychiatric disorders, closed-loop DBS attracting increasing attention as therapy. Using relational model identity and agency, consider whether for regulation may require special...

10.1080/21507740.2017.1320320 article EN AJOB Neuroscience 2017-04-03

Developing more and better diagnostic therapeutic tools for central nervous system disorders is an ethical imperative. Human research with neural devices important to this effort a critical focus of the National Institutes Health Brain Research Through Advancing Innovative Neurotechnologies (BRAIN) Initiative. Despite regulations standard practices conducting research, researchers others seek guidance on how ethically conduct device studies. This article draws on, reviews, specifies,...

10.1001/jamaneurol.2019.3523 article EN JAMA Neurology 2019-10-17

We argue that in implanted neurotechnology research, participants and researchers experience what Henry Richardson has called "moral entanglement." Participants partially entrust with access to their brains thus information would otherwise be private, leading created intimacies special obligations of beneficence for research funding agencies. One these obligations, we argue, is about continued beneficial technology once a trial ends. make the case moral entanglement this context through...

10.1002/hast.1566 article EN cc-by The Hastings Center Report 2024-01-01

Abstract Researchers are rapidly developing and deploying highly portable MRI technology to conduct field-based research. The new will widen access include investigators in remote unconventional settings facilitate greater inclusion of rural, economically disadvantaged, historically underrepresented populations. To address the ethical, legal, societal issues raised by accessible MRI, an interdisciplinary Working Group (WG) engaged a multi-year structured process analysis consensus building,...

10.1093/jlb/lsae008 article EN cc-by-nc-nd Journal of Law and the Biosciences 2024-01-01

Neural devices now under development stand to interact with and alter the human brain in ways that may challenge standard notions of identity, normality, authority, responsibility, privacy justice.

10.1002/hast.515 article EN The Hastings Center Report 2015-11-01

Neural devices have the capacity to enable users regain abilities lost due disease or injury – for instance, a deep brain stimulator (DBS) that allows person with Parkinson's ability fluently perform movements Brain Computer Interface (BCI) enables spinal cord control robotic arm. While recognize and appreciate technologies' maintain restore their capabilities, neuroethics literature is replete examples of concerns expressed about agentive capacities: A perceived lack over movement arm might...

10.1080/21507740.2021.1896599 article EN cc-by-nc-nd AJOB Neuroscience 2021-03-25

The BRAIN 2.0 roadmap lauds the neuroscientific advances made in first decade of Initiative, but also calls attention to need carefully consider how these will inform and perhaps alter our understanding “those deepest behaviors that, as humans we hold dear” (Roadmap, Executive Summary). In this short statement, briefly several features Neuroethics subgroup’s that lie within area expertise, including recommendations (1) enhance integration neuroscience neuroethics, (2) provide additional...

10.1080/21507740.2020.1778120 article EN AJOB Neuroscience 2020-07-02

Objective. Brain-computer interface (BCI) research and commercially available neural devices generate large amounts of data. These data have significant potential value to researchers industry. Individuals from whose brains derive may want exert control over what happens their at study conclusion or as a result using consumer device. It is unclear how BCI understand the relationship between users individuals should Approach. An online survey (n = 122) gathered perspectives on generated in...

10.1088/1741-2552/ab5b7f article EN Journal of Neural Engineering 2019-11-25

Brain-computer Interface (BCI) research is rapidly expanding, and it engages domains of human experience that many find central to our current understanding ourselves. Ethical principles or guidelines can provide researchers with tools engage in ethical reflection address practical problems research. Though have called for clearer guidelines, there little existing data on what form these should take. We developed a prospective set BCI specific shared them, via survey, participants at the 6th...

10.1080/2326263x.2018.1530010 article EN Brain-Computer Interfaces 2018-10-02

Despite advances in the care of injured patient, 22% trauma patients admitted to intensive unit will die from their injuries. As a majority these deaths occur due withdrawal care, intensivists should be proficient ability discuss end-of-life with and families. While use advance directives document patients' wishes has increased, utility is uncertain. We review effectiveness obstacles directives.

10.4103/2229-5151.84800 article EN International Journal of Critical Illness and Injury Science 2011-01-01

Neurotechnologies are rapidly being developed with the aim of alleviating suffering caused by disease and assisting individuals various disabilities. As capabilities applications neural devices advance, potential ethical challenges related to agency, identity, privacy, equality, normality justice have been noted. We sought explore attitudes toward these in two important, but understudied groups stakeholders—members device industry members general public. Survey responses from 66...

10.1080/21507740.2021.1896596 article EN AJOB Neuroscience 2021-03-31
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