- Electronic Health Records Systems
- Biomedical Text Mining and Ontologies
- Semantic Web and Ontologies
- Technology in Education and Healthcare
- Occupational Health and Safety in Workplaces
- Quality and Safety in Healthcare
- Data Quality and Management
- Healthcare Systems and Technology
- Telemedicine and Telehealth Implementation
- Chronic Disease Management Strategies
- Clinical practice guidelines implementation
- Mobile Health and mHealth Applications
- Healthcare Technology and Patient Monitoring
- Aging, Health, and Disability
- Scientific Computing and Data Management
- Ethics and bioethics in healthcare
- Health Systems, Economic Evaluations, Quality of Life
- Context-Aware Activity Recognition Systems
- Quality and Management Systems
- Cancer Genomics and Diagnostics
- Cardiac Health and Mental Health
- Engineering and Information Technology
- Research Data Management Practices
- Machine Learning and Data Classification
- Organizational Management and Innovation
Instituto de Salud Carlos III
2015-2025
Biomedical Research Institute
2023
Unidad de Investigación en cuidados y servicios de salud (Investén-isciii)
2013-2022
Centro de Investigación Biomédica en Red
2022
Digital Health Cooperative Research Centre
2021
Escuela Nacional de Sanidad
2016-2020
Fundación para el Fomento de la Investigación Sanitaria y Biomédica de la Comunitat Valenciana
2018
Centro de Investigación Biomédica en Red de Epidemiología y Salud Pública
2018
Universitat de Miguel Hernández d'Elx
2018
Universidad Publica de Navarra
2010
Chronic obstructive pulmonary disease (COPD) is frequent and often coexists with other diseases. The aim of this study was to quantify the prevalence COPD related chronic comorbidity among patients aged over 40 years visiting family practices in an area Madrid. An observational, descriptive, cross-sectional conducted a health Madrid Autonomous Region (Comunidad Autónoma de Madrid). practice population totalled 198,670 persons attended by 129 Family Physicians (FPs), made up age drawn from...
Introduction Healthcare management is oriented toward single diseases, yet multimorbidity nevertheless the rule and there a tendency for certain diseases to occur in clusters. This study sought identify comorbidity patterns patients with chronic by reference number of comorbidities, age sex, population receiving medical care from 129 general practitioners Spain, 2007. Methods A cross-sectional was conducted health-area setting Madrid Autonomous Region (Comunidad Autónoma), covering 198,670...
In Brief PURPOSE: Efficient ways are needed to implement the secondary prevention (SP) of coronary heart disease. Because few studies have investigated Web-based SP programs, our aim was determine usefulness a new telemonitoring system, connecting patients provided with self-measurement devices and care managers via mobile phone text messages, as tool for SP. METHODS: A single-blind, randomized controlled, clinical trial 203 acute syndrome (ACS) survivors, conducted at hospital in Madrid,...
A platform built around three information entities (patient, health-care/spl I.bar/agent, and central/spl I.bar/station) was designed to enable patients with chronic heart disease (in stable condition; emergency situations were excluded deliberately) complete specifically defined protocols for out-of-hospital follow-up monitoring. The belonged one of four specific risk groups: arterial hypertension, malignant arrhythmias, failure, postinfarction rehabilitation. They provided portable...
The evaluation in real-life settings of services for the follow-up and control hypertensive patients is a complex intervention, which still needs analysis roles, tasks, resources involved basic items: patient, healthcare professional, interaction between two. To evaluate impact patient-general practitioner (GP) short-messages-based interaction, isolated from other items, on degree hypertension medium-to-low-risk primary care, randomized controlled trial has been performed: 38 GPs enrolled...
COVID-19 ranks as the single largest health incident worldwide in decades. In such a scenario, electronic records (EHRs) should provide timely response to healthcare needs and data uses that go beyond direct medical care are known secondary uses, which include biomedical research. However, it is usual for each analysis initiative define its own information model line with requirements. These specifications share clinical concepts, but differ format recording criteria, something creates entry...
To discover new knowledge from data, they must be correct and in a consistent format. OntoCR, clinical repository developed at Hospital Clínic de Barcelona, uses ontologies to represent map locally defined variables health information standards common data models.The aim of the study is design implement scalable methodology based on dual-model paradigm use consolidate different organizations standardized for research purposes without loss meaning.First, relevant are defined, corresponding...
In order to maximize the value of electronic health records (EHRs) for both care and secondary use, it is necessary data be interoperable reusable without loss original meaning context, in accordance with findable, accessible, interoperable, (FAIR) principles. To achieve this, essential platforms incorporate standards that facilitate addressing needs such as formal modeling clinical knowledge (health domain concepts) well harmonized persistence, query, exchange across different information...
The standardization of Electronic Health Records (EHR) is a crucial factor for ensuring interoperable sharing health data. During recent decades, plethora initiatives ‐ driven by international organizations has emerged to define the required models describing exchange information between EHRs. These cover different essential characteristics building EHRs, such as architecture, methodology, communication, safety or terminology, among others. In this context, European reference frame...
Objective: The authors present an Electronic Healthcare Record (EHR) server, designed and developed as a proof of concept the revised prEN13606:2005 European standard concerning EHR communications. Methods: development server includes five modules: libraries for management reference model, demographic package data types; permanent storage module, built on relational database; two communication interfaces through which clients can send information or make queries; XML (eXtensible Markup...
This study aims to verify whether there is any relationship between the different classification outputs produced by distinct ML algorithms and relevance of data they classify, for addressing problem knowledge extraction (KE) from datasets. If such existed, main objective this research use it in order improve performance important task KE A new dataset generation a measurement methodology were developed check feature subsets (FSs) best classified specific algorithm correspond most...
This study aims to verify whether there is any relationship between the different classification outputs produced by distinct ML algorithms and relevance of data they classify, address problem knowledge extraction (KE) from datasets. If such a exists, main objective this research use it in order improve performance important task KE A new dataset generation measurement methodology were developed determine feature subsets (FSs) best classified specific algorithm corresponded most KE-relevant...
Background. Heart failure (HF) is a health problem that particularly affects the elderly population. Its onset associated with other chronic diseases, circumstance makes it challenge for care services. The aim of this study to quantify prevalence HF in family medicine offices and describe co-morbidity it. Methods. A cross-sectional, observational descriptive set area Community Madrid, Spain. was carried out population 198 670 individuals over 14 years age, attended by 129 specialists...
The results reported by different studies on telemonitoring in patients with chronic obstructive pulmonary disease (COPD) have been contradictory, without showing clear benefits to date. objective of this study was ascertain whether an early discharge and home hospitalization telehealth program for COPD exacerbation is as effective more efficient than a traditional program. A prospective experimental non-inferiority study, randomized into two groups (telemedicine/control) conducted....
Objectives: The aim of this study was to examine the impact late presentation (CD4 + cell count <350 cells/μl or an AIDS-defining event) on effectiveness and safety initial antiretroviral therapy (ART) evaluate whether treatment response depends first-line ART regimen in presenters. Design: ART-naive adults from Cohort Spanish HIV/AIDS Research Network (CoRIS) starting triple between 2010 2018. Methods: We used multivariable models assess differences viral suppression (viral load <50...
Abstract Despite the publication of great number tools to aid decisions in COVID-19 patients, there is a lack good instruments predict clinical deterioration. COVID19-Osakidetza prospective cohort study recruiting patients. We collected information from baseline discharge on: sociodemographic characteristics, comorbidities and associated medications, vital signs, treatment received lab test results. Outcome was need for intensive ventilatory support (with at least standard high-flow oxygen...
The new paradigm of personal health demands open standards and middleware components that permit transparent integration end-to-end interoperability from devices to healthcare information system. use seems be the internationally accepted way face this challenge. In article, implementation an standard-based solution is presented. It integrates ISO/IEEE11073 standard for in patient environment ISO/EN13606 interoperable exchange electronic records proposes a approach ISO/IEEE11073-ISO/EN13606...
The availability of electronic health data favors scientific advance through the creation repositories for secondary use. Data anonymization is a mandatory step to comply with current legislation. A service pseudonymization healthcare record (EHR) extracts aimed at facilitating exchange clinical information use in compliance legislation on protection presented. According ISO/TS 25237, particular type anonymization. This tool performs anonymizations by maintaining three quasi-identifiers...
This research shows a protocol to assess the computational complexity of querying relational and non-relational (NoSQL (not only Structured Query Language)) standardized electronic health record (EHR) medical information database systems (DBMS). It uses set three doubling-sized databases, i.e. databases storing 5000, 10,000 20,000 realistic EHR extracts, in different management (DBMS): MySQL object-relational mapping (ORM), document-based NoSQL MongoDB, native extensible markup language...
The objective of this research is to compare the relational and non-relational (NoSQL) database systems approaches in order store, recover, query persist standardized medical information form ISO/EN 13606 normalized Electronic Health Record XML extracts, both isolation concurrently. NoSQL have recently attracted much attention, but few studies literature address their direct comparison with databases when applied build persistence layer a system. One two (one document-based one native...
Background.In order to ensure proper management of primary care (PC) services, the efficiency health professionals tasked with such services must be known. Patients heart failure (HF) are characterized by advanced age, high co-morbidity and resource utilization.
Objective Most patients with mild COVID-19 had to stay at home trying implement an optimal quarantine. The aim of this study was describe the cases during first wave pandemic in Spain, how they managed disease home, focusing on differences by age, as well knowledge, attitudes and preventive practices, compared uninfected population. Design An online survey used conduct a cross-sectional individuals who were 14 years or older living Spain lockdown. main variable case. Logistic regression...