A5074369001- Cardiac Valve Diseases and Treatments
- Acute Myocardial Infarction Research
- Cardiac, Anesthesia and Surgical Outcomes
- Cardiac and Coronary Surgery Techniques
- Cardiovascular Function and Risk Factors
- Heart Failure Treatment and Management
- Infective Endocarditis Diagnosis and Management
- Atrial Fibrillation Management and Outcomes
- COVID-19 and Mental Health
- Coronary Interventions and Diagnostics
- Healthcare professionals’ stress and burnout
- Pulmonary Hypertension Research and Treatments
- Venous Thromboembolism Diagnosis and Management
- Health Systems, Economic Evaluations, Quality of Life
- Cardiac Arrhythmias and Treatments
- Ectopic Pregnancy Diagnosis and Management
- Cardiovascular and Diving-Related Complications
- Sex work and related issues
- Circular RNAs in diseases
- Blood Coagulation and Thrombosis Mechanisms
- Cardiac electrophysiology and arrhythmias
- Geriatric Care and Nursing Homes
- Emergency and Acute Care Studies
- Uterine Myomas and Treatments
- HIV/AIDS Impact and Responses
Leeds General Infirmary
2022-2025
Society of Interventional Radiology
2024
Blackpool Teaching Hospitals NHS Foundation Trust
2020-2023
Leeds Teaching Hospitals NHS Trust
2022
Zagazig University
2020-2022
Le Moyne College
2021
Wildlife Information Liaison Development
2021
University of Liverpool
2019-2021
Blackpool Victoria Hospital
2019-2021
Airedale NHS Foundation Trust
2021
Readers are invited to submit letters for publication in this department. Submit online at ht∗∗tp://joem.edmgr.com. Choose "Submit New Manuscript." A signed copyright assignment and financial disclosure form must be submitted with the letter. Form available www.joem.org under Author Reviewer information. To Editor: The United Kingdom's National Health Service (NHS), along other health services around world, faces unprecedented pressures dealing COVID-19 pandemic.1 stress on NHS is not...
Infective endocarditis, typically caused by Gram-positive organisms such as viridans group streptococci and Staphylococcus aureus, is associated with high mortality morbidity requires aggressive, prolonged antimicrobial treatment sometimes surgery. Dalbavancin, a lipoglycopeptide active against pathogens, has long half-life, which allows IV one dose or two doses interval, offering personalized for complex psychosocial situations facilitating early discharge. In the absence of randomized...
Increasing demand for transcatheter aortic valve implantation (TAVI) places greater emphasis on the efficiency of pathways and services. A significant limitation to increasing TAVI capacity is availability cardiac catheterisation laboratory time. We have developed a novel complexity scoring system (TAVI ComplEXity; TEX score) which can aid in planning lists with appropriate case selection. To validate score, we undertaken retrospective analysis cases. The hypothesis that score correlates...
Elevated left ventricular end diastolic pressure (LVEDP) following transcatheter aortic valve implantation (TAVI) has been identified as a predictor of heart failure and mortality. To determine whether change in LVEDP is more powerful adverse clinical outcomes than elevated post-TAVI. Patients who underwent TAVI at two high volume centers between January 2013 December 2023 were screened for inclusion. measurements taken before immediately after TAVI. Hospital records analyzed mortality...
To ascertain the level of psychological distress, using validated psychology tools, among British National healthcare workers (HCW) during first wave Covid-19 crisis.A multi-centre, anonymized, all-comer staff survey across 3 hospitals in Lancashire, England (April to June 2020), consisting Patient Health Questionnaire (PHQ-9), Perceived Stress Scale-10 (PSS-10), Generalized Anxiety Disorder-7 (GAD-7), and Impact Events Scale (IES-6).Among 1113 HCW, median (IQR) PHQ-9, GAD-7, PSS-10, IES-6...
Acute heart failure (AHF) hospitalisation is associated with 10% mortality. Outpatient based management (OPM) of AHF appeared effective in observational studies. We conducted a pilot randomised controlled trial (RCT) comparing OPM standard inpatient care (IPM).We patients AHF, considered to need IV diuretic treatment for ≥2 days, IPM or OPM. recorded all-cause mortality, and the number days alive out-of-hospital (DAOH). Quality life, mental well-being Hope scores were assessed. Mean NHS cost...
Patients with prior coronary artery bypass graft (CABG) surgery often require percutaneous intervention (PCI). Data are still limited in regards to the outcomes of native saphenous vein (SVG) PCI after CABG.We performed a retrospective study tertiary reference cardiac center consecutive patients who underwent CABG. The data were collected for either or from January 2008 December 2018. Arterial PCIs excluded. Multivariable Cox regression analysis propensity matching was performed, and major...
Ovarian cancer is the fifth leading cause of cancer-related deaths among women worldwide. Unfortunately, early detection tests are relatively lacking. Diagnosis in late stages disease carries a poor prognosis.To evaluate relationship between miR-196a-2 rs11614913 polymorphism and ovarian risk prognosis Egyptian females.In this case-control study, participants were classified into 2 groups. Group A control group which included 50 healthy females. B patients newly diagnosed with carcinoma...
Right ventricular (RV) impairment may have prognostic value in patients undergoing mitral valve surgery. It is unclear whether RV dysfunction predicts long-term mortality, especially the era of minimally invasive surgery.We performed a retrospective analysis consecutive referred for conventional (via sternotomy) and surgery (MIMVS) between 01 January 2013 29 August 2018 tertiary cardiac centre. We truncated follow-up times at 25 March 2020. was defined by reduced longitudinal function (TAPSE...
<h3>Introduction</h3> Acute heart failure (AHF) hospitalisation is typically lengthy, costly and associated with 10% mortality. Outpatient based management (OPM) of AHF appeared effective in observational studies. We conducted a pilot randomised controlled trial (RCT) comparing OPM standard inpatient care (IPM). Hopelessness independently predicted mortality patients risk factors ischaemic disease. hypothesize that to may be more hopeful have better mental well-being, quality life, patient...
The purpose of our survey is to analyze the clinical approach used by interventional and imaging cardiologists diagnose, treat, follow-up patients with PFO-related left circulation thromboembolism in different parts world particular emphasis on adherence current guidelines.Firm guidelines do not cover many aspects patient care. Consequently, very disparate approaches exist among clinicians real-world.A 24-item electronic questionnaire was sent directly experienced cardiology specialists...
Multiple studies have suggested that women worse outcomes than men following mitral valve (MV) surgery-most of those reported on conventional sternotomy (CS) MV surgery. Therefore, we aimed to explore whether or not the minimally invasive surgery (MIMVS) approach might mitigate a survival in surgery.We identified patients with isolated primary operations without tricuspid repair performed between 2007 and 2019. Patients were propensity score-matched across MIMVS CS surgical approaches. Sex...
<h3>Introduction</h3> Outpatient based management of heart failure is gaining popularity in the UK. Observation data and a small pilot randomised controlled trial suggested it safe clinically effective. However, cost-effectiveness this novel treatment approach not known. Patient level costing thought to be more accurate providing extra granularity when reviewing cost patient pathways. <h3>Methods</h3> We used Trust's models from financial years 2018/19 2019/20 calculate total costs for...
<h3>Introduction</h3> Worsening heart failure (HF) leading to hospital admission is common and associated with substantial morbidity mortality. For many patients, the preferred place of care, including end-of-life at home or in community, but this often thwarted by need for intravenous (IV) diuretic therapy. Alternative models ambulatory care exist safety efficacy should be compared standard randomised controlled trials (RCT). <h3>Methods</h3> We patients pulmonary peripheral oedema who no...
Background: The definition of infertility is one year unprotected intercourse with no pregnancy among married couples. Objective:The aim the study to assess efficacy and safeness combined hysterolaproscopy on evaluation management female infertility.Patients Methods: A prospective clinical triad was carried 416 patients infertile women aged between 18 42 years either primary or secondary normal hormone profile without male factor at Cytogenetics Endoscopy Unit, Zagazig University.Those...
<h3>Introduction</h3> Right ventricular (RV) impairment may have prognostic value in patients undergoing mitral valve surgery. However, studies yielded conflicting data. It is unclear whether RV dysfunction predicts long-term mortality, especially mini-mitral era. <h3>Methods</h3> We performed a retrospective analysis of consecutive referred from Blackpool, Blackburn, Chorley, Lancaster hospitals for surgery between January 2013 and December 2015. The were followed-up up to 6 years. Censor...
Introduction Wide experimental evidence has proved Alpha 1 antitrypsin, which is released from the liver, to protect lung tissue damage during inflammation. There also suggests such protection extended myocardial tissues ischemia/infarction. Objective The aim of study was determine levels and time course A1AT in plasma infarction patients over 96 hours compare it with healthy subject as control. Methods Blood samples were collected (n=40) arriving at emergency department 1, 4, 24, 48 hrs...
Abstract Background Patients with prior coronary artery bypass graft (CABG) surgery often require percutaneous intervention (PCI). Data are still limited in regards to the outcomes of native versus PCI after CABG. Methods We performed a retrospective study tertiary reference cardiac centre consecutive patients who underwent The data were collected for either or from January 2008 December 2018. Major adverse events (MACE) included death myocardial infarction (MI) revascularization. All...