A5090113926- Pregnancy and preeclampsia studies
- Fetal and Pediatric Neurological Disorders
- Birth, Development, and Health
- Prenatal Screening and Diagnostics
- Neonatal and fetal brain pathology
- Gestational Diabetes Research and Management
- Advanced MRI Techniques and Applications
- Maternal and fetal healthcare
- Colorectal and Anal Carcinomas
- Cervical Cancer and HPV Research
- Grief, Bereavement, and Mental Health
- Assisted Reproductive Technology and Twin Pregnancy
- Endometrial and Cervical Cancer Treatments
- Maternal and Perinatal Health Interventions
- Autopsy Techniques and Outcomes
- Advanced Neuroimaging Techniques and Applications
- Cancer and Skin Lesions
- Ethics and Legal Issues in Pediatric Healthcare
- Bariatric Surgery and Outcomes
- Salivary Gland Tumors Diagnosis and Treatment
- Organ Donation and Transplantation
- Cardiovascular Health and Disease Prevention
- Cancer Risks and Factors
- Reproductive Health and Technologies
- MRI in cancer diagnosis
Harris Birthright Research Centre for Fetal Medicine
2022-2025
King's College London
2022-2025
King's College Hospital
2022-2025
King's College Hospital NHS Foundation Trust
2025
Lund University
2017-2022
Skåne University Hospital
2016-2021
Vilnius University
2013-2016
Abstract Background Artificial intelligence (AI) has shown potential in improving the performance of screening fetal anomaly ultrasound scans. We aimed to assess effect AI on scanning, terms diagnostic performance, biometry, scan duration, and sonographer cognitive load. Methods This was a randomised, single centre, open label trial large teaching hospital. Pregnant participants with congenital heart disease (CHD) healthy fetuses were recruited scanned both methods. Screening sonographers...
ABSTRACT Objective The objective of this study is to examine the association between dietary calcium intake (Ca) and pre‐eclampsia (PE). Design Cohort study. Setting Inner‐city hospital. Population A total 2838 women with singleton pregnancies at 35 +0 –36 +6 weeks' gestation, including 96 (3.4%) who subsequently developed PE. Methods Online 24‐h recall questionnaire was used measure Ca intake. In low (< 700 mg/d) vs. adequate (≥ groups, we compared prevalence PE‐associated maternal risk...
Cervical intraepithelial neoplasia (CIN) is a dysplastic process in cervical squamous epithelium and carries risk of progression to cancer. The aim this study was compare expression three biomarkers named p53, p63 Ki-67 patients with various grades control group.58 were enrolled the study. Each patient underwent colposcopy-guided biopsy cervix. Immunostaining for markers (p53, Ki-67) performed on tissue samples normal cases (n=10), CIN I (n=20), II (n=14), III (n=14).Our showed significant...
To examine the relationship between English index of multiple deprivation (IMD) and incidence pre-eclampsia (PE), evaluate distribution IMD in a cohort ethnically diverse pregnant women South East England assess whether improves prediction PE compared with that provided by 'history-only' competing-risks model (based on maternal characteristics medical history).This was prospective, observational study 159 125 singleton pregnancy who attended their first routine hospital visit at 11 + 0 to 13...
Accurate identification of independent predictors stillbirth is needed to define preventive strategies. We aim examine the contribution maternal race in risk after adjusting for characteristics and medical history. There are two components study: first, prospective screening 168,966 women with singleton pregnancies coordinated by Fetal Medicine Foundation (FMF) second, a systematic review meta-analysis studies reporting on stillbirth. In FMF study, logistic regression analysis found that...
Tumors originating from ceruminous glands are rare lesions of the external auditory canal. The lack specific clinical and radiological signs makes their diagnosis challenging. We report case an exceptionally benign tumor, a syringocystadenoma papilliferum (SCAP), in atypical location bony segment canal with uncommon signs. special traits included following: most lateral component tumor was macroscopically cystic granular myringitis obstructing keratin mass plug observed behind mass....
ABSTRACT Objective To validate and extend a model incorporating maternal ophthalmic artery Doppler at 35–37 weeks' gestation in the prediction of subsequent development pre‐eclampsia (PE). Methods This was prospective validation study screening for PE (defined according to 2019 American College Obstetricians Gynecologists criteria) by peak systolic velocity (PSV) ratio 6746 singleton pregnancies undergoing routine care 35 + 0 36 6 (validation dataset). Additionally, data from dataset were...
ABSTRACT Objectives To examine the vascular phenotype at 35–37 weeks' gestation of women with gestational diabetes mellitus (GDM) and compare it to that in without GDM, using ophthalmic artery Doppler carotid–femoral pulse‐wave velocity. Methods This was a prospective observational study attending for routine hospital visit 35 + 0 37 6 gestation. included recording maternal demographic characteristics medical history, calculation peak systolic velocity (PSV) ratio assessment cardiac output,...
First, to compare ophthalmic artery peak systolic velocity (PSV) ratio and biomarkers of impaired placentation at 36 weeks' gestation in women who delivered a small-for-gestational-age (SGA) or growth-restricted (FGR) neonate, the absence hypertensive disorder, with those developed pre-eclampsia (PE) gestational hypertension (GH) unaffected by SGA, FGR, PE GH. Second, examine associations PSV ratio, uterine pulsatility index (UtA-PI), placental growth factor (PlGF) soluble fms-like tyrosine...
ABSTRACT Objectives To examine the relationship between English index of multiple deprivation (IMD) and incidence stillbirth assess whether IMD contributes to prediction provided by combination maternal demographic characteristics elements medical history. Methods This was a prospective, observational study 159 125 women with singleton pregnancy who attended their first routine hospital visit at 11 + 0 13 6 weeks' gestation in two maternity hospitals UK. The inclusion criterion delivery ≥ 24...
Objective: To compare pre-eclampsia (PE) risk strategies among Black vs. White ethnicity women. Design: Prospective non-intervention cohort studies. Setting: Maternity hospitals, United Kingdom and Europe. Population: Singleton pregnancies delivering at ≥24 weeks, without major anomalies. Methods: PE was determined by National Institute for Health Care Excellence (NICE) guidance, NICE guidance modified adding as a moderate-risk factor, the Fetal Medicine Foundation (FMF) competing-risks...
Magnetic resonance imaging (MRI) in combination with real-time ultrasound (US) may improve prenatal examination of fetal malformations. The objective this case report was to optimise scanning cerebral abnormality. We a previously healthy woman, 3 gravida, 2 normal deliveries. Normal US at 19th week gestation. 32 weeks gestation showed the presence x 25 mm translucent area, frontal brain suggested be subdural hematoma or cyst. There were no anatomical defects midline, cavum septum pellucidum,...
Magnetic resonance imaging (MRI) in combination with real time ultrasound (US) has been introduced several medical fields. Fusion may have a potential to improve prenatal assessment of placental and uterine wall abnormalities. US MRI were combined by use sophisticated navigation system (Philips Epiq) corresponding markers. A volume was obtained real-time performed. One patient vanishing twin pregnancy after IVF procedure dorsal invasive placenta suspected at an early examination. performed...
( BJOG . 2022;129:2082–2093) Pre-eclampsia is a complication affecting 2% to 4% of pregnancies and associated with high rate maternal infant mortality. The risk developing pre-eclampsia related age, weight, race, method conception, personal family history, pre-existing conditions. Studies from predominantly white countries have indicated that some minority groups an increased incidence pre-eclampsia, other decreased or similar women. These studies, however, mostly observed relative without...
The aim was to assess synchronisation of the MRI and US on a fetus phantom by using different numbers matching landmarks as well inter-observer difference between fetal head brain structure measurements. FI performed combining simultaneously. Biometric ultrasound training (CIRS, Virginia, USA) used. 1,5 Tesla sagittal scans (1 mm slices) were acquired images uploaded machine (EPIQ 7G, Philips). PercuNav tracker fixed probe thus allowing system recognise display position orientation...
To estimate the prevalence and types of congenital uterine anomalies at three-dimensional (3D) ultrasound examination in gynecologically healthy premenopausal women, to describe uterus morphology assess reproductive outcomes women with detected anomalies. Gynecologicaly 656 20–39 years age were recruited from Swedish population registry. Two-dimensional (2D) 3D was performed. GE E8 system (Milwaukee, WI, USA) a 6-12 MHz transvaginal transducer used. The analyses stored volumes performed...
Objectives: To examine the association between racial origin and preeclampsia(PE) gestational hypertension(GH) after adjustment for factors in maternal characteristics medical history screening study from Fetal Medicine Foundation (FMF) England, to perform a systematic review meta-analysis of studies on PE. Methods: In FMF data regression analysis was performed PE or GH. Literature search December 2021 carried out identify peer-reviewed publications race Main outcome measure: Relative risk...