Tuan‐Jen Fang

ORCID: 0000-0002-0164-3724
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About
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Research Areas
  • Voice and Speech Disorders
  • Head and Neck Cancer Studies
  • Tracheal and airway disorders
  • Dysphagia Assessment and Management
  • Obstructive Sleep Apnea Research
  • Neuroscience of respiration and sleep
  • Salivary Gland Tumors Diagnosis and Treatment
  • Head and Neck Surgical Oncology
  • Lung Cancer Treatments and Mutations
  • Cancer Diagnosis and Treatment
  • Ear and Head Tumors
  • Head and Neck Anomalies
  • Respiratory and Cough-Related Research
  • Phonetics and Phonology Research
  • Oral Health Pathology and Treatment
  • Esophageal Cancer Research and Treatment
  • Nasal Surgery and Airway Studies
  • Reconstructive Surgery and Microvascular Techniques
  • Cleft Lip and Palate Research
  • Colorectal and Anal Carcinomas
  • Esophageal and GI Pathology
  • Sleep and related disorders
  • Tumors and Oncological Cases
  • Thyroid and Parathyroid Surgery
  • Sleep and Wakefulness Research

Linkou Chang Gung Memorial Hospital
2016-2025

Chang Gung Memorial Hospital
2015-2025

Chang Gung University
2016-2025

Taoyuan Chang Gung Memorial Hospital
2020

Molina Center for Energy and the Environment
2020

Restaurant Opportunities Centers United
2016

Bridge University
2016

Xiamen Chang Gung Hospital
2014-2015

Memorial Hospital of South Bend
2002-2013

University of California, San Francisco
2011

Surgery for oesophageal squamous cell carcinoma involves dissecting lymph nodes along the recurrent laryngeal nerve. This is technically challenging and injury to nerve may lead vocal cord palsy, which increases risk of pulmonary complications. The aim this study was compare efficacy safety robot-assisted oesophagectomy (RAO) versus video-assisted thoracoscopic (VAO) dissection left RLN.

10.1093/bjs/znae143 article EN cc-by-nc British journal of surgery 2024-07-01

The question as to whether prolonged diagnosis-to-surgery intervals (DSIs) may compromise survival outcomes in patients with oral cavity squamous cell carcinoma (OCSCC) remains unanswered. This nationwide study was designed address this issue. We analyzed data from 26,214 first primary OCSCC identified the Taiwanese Cancer Registry Database between 2011 and 2021. optimal DSI cutoff determined based on 5-year disease-specific (DSS) overall (OS) rates using Cox regression analysis. Patients...

10.1016/j.oraloncology.2025.107196 article EN cc-by-nc Oral Oncology 2025-01-21

Objective: To evaluate the impact of nasal surgery alone on quality life (QOL) in patients with obstructive sleep apnea and obstruction using generic diseasespecific QOL questionnaires.Design: Prospective, longitudinal cohort study.Patients: Fifty-one consecutive (50 men 1 woman; mean age, 39 years; [SD] apnea-hypopnea index, 37.4 [28.9] events/h; ± SD body mass index [calculated as weight kilograms divided by height meters squared], 26.0 [3.5]) symptoms due to a deviated...

10.1001/archotol.134.4.429 article EN Archives of Otolaryngology - Head and Neck Surgery 2008-04-01

To evaluate and compare outcomes of uvulopalato-pharyngoplasty (UPPP) for obstructive sleep apnea/hypopnea syndrome (OSAHS) using anatomy- severity-based staging systems. Prospective design with a retrospective review. A tertiary-care, disorder referral center. In total, 110 patients OSAHS (105 men, 5 women; mean age, 43 years; apnea-hypopnea index, 44.4 ± 28.8 events per hour; body mass 27.1 3.3 kg/m2). An anatomy-based system (stages I–IV) was used to classify by examining tongue-palate...

10.1093/sleep/29.12.1537 article EN SLEEP 2006-12-01

Abstract Objectives/Hypothesis: Children with sleep‐disordered breathing may experience behavioral and learning problems such as inattentiveness hyperactivity. The aim of this study was to measure the impact adenotonsillectomy on sleep‐related adverse events in children breathing. Method: This prospective interventional enrolled 40 (mean age, 8.4 ± 1.6 years) hypertrophic tonsils adenoids. All patients completed two polysomnographies, tests variables attention (TOVAs), Child Behavior...

10.1097/01.mlg.0000217542.84013.b5 article EN The Laryngoscope 2006-07-01

Abstract Background The purpose of this study was to investigate whether multidisciplinary team care (MDTC) is associated with outcomes in oral cavity squamous cell carcinoma (SCC). Methods We retrospectively examined 1616 patients SCC who underwent radical surgery between 1996 and 2011. participants were classified into 2 subgroups according the use MDTC. Results Five‐year significantly better MDTC group than no‐MDTC (neck control, 88% vs 84%, p = .0397; disease‐specific survival [DSS], 83%...

10.1002/hed.24276 article EN Head & Neck 2016-02-18

Before caring for patients, video instruction is commonly used undergraduate medical students, and 360° virtual reality (VR) videos have gained increasing interest in clinical education. Therefore, the effect of immersive VR learning compared with two-dimensional (2D) skills acquisition should be evaluated. This randomized, intervention-controlled trial was aimed to assess whether improves students' effectiveness reduces cognitive load history taking physical examination (H&P) training. From...

10.1007/s10055-022-00664-0 article EN cc-by Virtual Reality 2022-08-16

Abstract Objectives: Papillomas of the larynx include solitary laryngeal papilloma and recurrent respiratory papillomatosis. This study investigated incidence malignant transformation assessed possible risk factors for papillomas. Study Design: A prospective, longitudinal study. Methods: Twenty‐six consecutive patients were prospectively studied 5 or more years, each patient was periodically examined at 3 to 6 month intervals. detailed epidemiologic questionnaire administered initial visit....

10.1097/mlg.0b013e318155a288 article EN The Laryngoscope 2008-01-01

To investigate the quality of life (QoLF) status Taiwanese adults with unilateral vocal cord paralysis (UVCP).A prospective, QoLF survey in a tertiary referral voice center.Fifty-five consecutive UVCP patients were evaluated Medical Outcome Study Short Form-36 (SF-36) Health Survey and outcome at entry.UVCP have significantly lower scores all eight SF-36 subscales (P < .05) than do normative Taiwan adult population, particularly role functioning-physical problems, social functioning,...

10.1097/mlg.0b013e31817e7431 article EN The Laryngoscope 2008-09-24

To evaluate the efficacy of nasal surgery to relieve snoring and identify predictive factors.Prospective comparative study.Fifty-two consecutive patients (51 males; mean age, 38 yr; body mass index, 25.4 +/- 5.2 kg/m2) were enrolled. All had been previously diagnosed with obstructive sleep apnea (apnea/hypopnea 38.5 33.2 events/hr) symptomatic obstruction secondary deviated septum. Septomeatoplasty alone was treatment in this study cohort. Snoring assessed by Snore Outcome Survey (SOS),...

10.1097/mlg.0b013e318158f73f article EN The Laryngoscope 2008-02-01

Background Annoying snore is the principle symptom and problem in obstructive sleep apnea syndrome (OSAS). However, investigation has been hampered by complex snoring sound analyses. Objective This study was aimed to investigate energy types of full-night sounds patients with OSAS. Patients Method Twenty male OSAS underwent recording throughout 6 hours in-lab overnight polysomnogragphy. Snoring were processed analyzed a new analytic program, named as Snore Map®. We transformed 6-hour power...

10.1371/journal.pone.0053481 article EN cc-by PLoS ONE 2012-12-31

Vocal cord leukoplakia comprises a variety of lesions. The purpose this study was to stratify vocal leukoplakias before surgery.Patients with an initial diagnosis who underwent surgical excision at tertiary referral center in Taiwan were recruited for study. Their clinical records, including age, sex, preoperative laryngoscopic images the office setting, and final pathology reports collected analyzed.Patient age (p = .010), nonhomogenous lesion texture .001), existence hyperemia .014)...

10.1002/hed.24368 article EN Head & Neck 2016-02-05

To investigate the neurologic and functional effect of intracordal hyaluronate injections in acute unilateral vocal fold paralysis (UVFP) a randomized controlled trial.In this open-label, study, 29 patients with UVFP were recruited within 6 months their first outpatient visit to receive either single injection (HI group) or conservative management (CM group). Quantitative laryngeal electromyography, videolaryngostroboscopy, UVFP-related quality life (Voice Outcomes Survey, VOS), laboratory...

10.3233/rnn-140439 article EN Restorative Neurology and Neuroscience 2015-01-01

Abstract Obstructive sleep apnea (OSA) is a known risk factor for atherosclerosis. We investigated the association of common carotid artery intima-media thickness (CCA-IMT) with snoring sounds in OSA patients. A total 30 newly diagnosed patients no history cardiovascular diseases were prospectively enrolled measuring mean CCA-IMT B-mode ultrasonography, body mass index, metabolic syndrome, 10-year disease score, high-sensitivity C-reactive protein, and homocysteine. Good-quality signals...

10.1038/srep30559 article EN cc-by Scientific Reports 2016-07-29

Both obstructive sleep apnea (OSA) and obesity are major health issues that contribute to increased systemic inflammation in children. To date, adenotonsillectomy (AT) is still the first-line treatment for childhood OSA. However, relationships among predictive values of obesity, inflammation, OSA severity have not been comprehensively investigated. This prospective study investigated body mass index (BMI), serum inflammatory markers, before after AT 60 pediatric patients with At baseline,...

10.3390/jcm9020579 article EN Journal of Clinical Medicine 2020-02-20

This study assessed changes in sleep-related symptoms and polysomnographic parameters after nasal surgery for obstruction obstructive sleep apnea (OSA) adults Taiwan.A total of 66 patients with OSA chronic were recruited (surgical, n = 44; control, 22). Nasal alone was the treatment surgical patients. Outcomes measured a Snore Outcome Survey (SOS), Epworth Sleepiness Scale (ESS), rhinomanometry, at baseline again 3 months.Significantly improved resistance as by SOS ESS found only group (all,...

10.2500/ajra.2009.23.3358 article EN American Journal of Rhinology and Allergy 2009-11-01

Objectives/Hypothesis The impact of margin status on the outcomes early glottic cancer after endoscopic resection is controversial; second look laryngoscopy has shown a low rate residual cancer, even in positive patients. Intraoperative frozen section analysis been suggested as an alternative to routine procedures. aim this study was evaluate and search for predictors patients following based intraoperative analysis. Study Design Retrospective chart review. Methods Records consecutive...

10.1002/lary.23875 article EN The Laryngoscope 2013-02-09

Objective To examine the effect of positional dependency on surgical success among patients with severe obstructive sleep apnea (OSA) following modified uvulopalatopharyngoplasty, known as relocation pharyngoplasty. Study Design Case series planned data collection. Setting Tertiary referred center. Subjects and Methods Standard nocturnal polysomnography was used to compare apnea‐hypopnea index (AHI) in different positions before after pharyngoplasty 47 consecutive OSA (AHI, 59.5 ± 18.2...

10.1177/0194599813495663 article EN Otolaryngology 2013-07-01
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