A5067442691- Genomics and Phylogenetic Studies
- Healthcare Education and Workforce Issues
- Plant and Fungal Species Descriptions
- Education and Learning Interventions
- Plant Pathogens and Fungal Diseases
- Educational Systems and Policies
- Diverse Approaches in Healthcare and Education Studies
- Fern and Epiphyte Biology
- Plant Diversity and Evolution
- Genetic diversity and population structure
- Psychosocial Factors Impacting Youth
- Job Satisfaction and Organizational Behavior
- Acute Ischemic Stroke Management
- Garlic and Onion Studies
- Biochemical and Structural Characterization
- Agriculture, Soil, Plant Science
- Photosynthetic Processes and Mechanisms
- Grit, Self-Efficacy, and Motivation
- Ecology and Conservation Studies
- Gene expression and cancer classification
- Cerebrovascular and Carotid Artery Diseases
- Plant and animal studies
- Chromosomal and Genetic Variations
- Reproductive System and Pregnancy
- Bioinformatics and Genomic Networks
Seoul National University
2009-2025
Kangwon National University
2012-2025
Institute of Botany
2017-2024
Chinese Academy of Sciences
2017-2024
Yuhan University
2023-2024
University of Chinese Academy of Sciences
2017-2020
Gyeongsang National University Hospital
1993-2020
Gyeongsang National University
2018
National Institute of Biological Resources
2016-2017
Korea Institute of Toxicology
2014
Abstract The human body louse, Pediculus humanus , has one of the smallest insect genomes, containing ∼10 775 annotated genes. Annotation detoxification [cytochrome P450 monooxygenase (P450), glutathione‐S‐transferase (GST), esterase (Est) and ATP‐binding cassette transporter (ABC transporter)] genes revealed that they are dramatically reduced in P. h. compared to other insects except for Apis mellifera . There 37 P450, 13 GST 17 Est present approximately half number found Drosophila...
Abstract Transcriptional profiling results, using our non‐invasive induction assay {short exposure intervals (2–5 h) to sublethal amounts of insecticides [<lethal concentration 3% (LC 3 ) at 24 h] administered by stress‐reducing means (contact vs. immersion screen) and with assessed in a time frame when tolerance is still present [∼lethal 90% 90 2–4 h]}, showed that ivermectin‐induced detoxification genes from body lice are identified quantitative real‐time PCR analyses. Of the cytochrome...
The eupolypods II ferns represent a classic case of evolutionary radiation and, simultaneously, exhibit high substitution rate heterogeneity. These factors have been proposed to contribute the contentious resolutions among clades within this fern group in multilocus phylogenetic studies. We investigated deep relationships eupolypod by sampling all major families and using 40 plastid genomes, or plastomes, which 33 were newly sequenced with next-generation sequencing technology. performed...
This study elucidates the mechanism of physiological effect cannabidiol (CBD) by assessing its impact on lipopolysaccharide (LPS)-induced inflammation in RWPE-1 cells and prostatitis-induced 17β-estradiol dihydrotestosterone a rat model, focusing therapeutic potential for chronic prostatitis/chronic pelvic pain syndrome (CP/CPPS).
Peucedanum japonicum (PJ), a member of the Apiaceae family, is widely distributed and cultivated in East Asian countries for edible functional foods. In this study, we compared plastid genomes (plastomes) 45S nuclear ribosomal DNA (45S nrDNA) simultaneously from 10 PJ collections. Plastome-based phylogenetic analysis showed that accessions were monophyletic within genus Peucedanum. However, ten plastomes classified into two different groups according to their length inverted repeat (IR)...
Summary Plastids and mitochondria are endosymbiotic organelles that store genetic information. The genomes of these generally exhibit contrasting patterns regarding genome architecture content. However, they have similar features in Selaginellaceae, little is known about what causes parallel evolution. Here, we document the multipartite plastid (plastomes) highly divergent mitochondrial (mitogenomes) from spikemoss obtained by combining short‐ long‐reads. 188‐kb plastome has three ribosomal...
Summary Loop‐mediated isothermal amplification ( LAMP ) detection tools have great potential for diagnosing the causal agents of infectious diseases in clinics and agriculture. In this work, we developed two alternative protocols detecting pathogenic nematode Bursaphelenchus xylophilus , agent pine wilt disease. We first identified a pectate lyase 3 gene as biomarker developing Detection Kit, there was no homologue non‐pathogenic nematodes that live timber or bark show structural...
Two factors are proposed to account for the unusual features of organellar genomes: disruptions organelle-targeted DNA replication, repair, and recombination (DNA-RRR) systems in nuclear genome repetitive elements genomes. Little is known about how these affect evolution. The deep-branching vascular plant family Selaginellaceae have a deficient DNA-RRR system convergently evolved However, we found that plastid (plastome) Selaginella sinensis has extremely accelerated substitution rates, low...
Licorice (Glycyrrhiza L.), a medicinally and economically significant genus in the Fabaceae, is known for synthesizing glycyrrhizin. Here, we present newly assembled genome of Glycyrrhiza uralensis, key species distributed across Central East Asia. Using Oxford Nanopore, Hi-C, Illumina sequencing, 415 Mbp with an N50 47 Mbp. While structure was similar to previously reported assemblies, structural variations were observed all eight chromosomes. Re-sequencing data from 29 individuals,...
ABSTRACT The CRISPR‐Cas system is an adaptive immune in prokaryotes that provides protection against bacteriophages. As a countermeasure, bacteriophages have evolved various anti‐CRISPR proteins neutralize immunity. Here, we report the structural and functional investigation of AcrIE7, which inhibits type I‐E Pseudomonas aeruginosa . We determined both crystal solution structures revealed novel helical fold. In binding assays using biochemical methods, AcrIE7 did not tightly interact with...
Abstract Deer velvet (DV) is an oriental traditional medicine used to treat various diseases. The present study examined the effect of flavourzyme-derived DV extract (YC-1101) on macrophages and immunosuppressed mouse model. YC-1101 induced activation as measured by nitric oxide production, cell proliferation, cytokine release via concentration-dependent phosphorylation c-Jun N-terminal kinase, extracellular signal-regulated AKT, nuclear translocation p65 in macrophages. In addition, oral...
The complete chloroplast genomes of Lychnis wilfordii and Silene capitata were determined compared with ten previously reported Caryophyllaceae genomes. genome sequences L. S. contain 152,320 bp 150,224 bp, respectively. gene contents orders among 12 species are consistent, but several microstructural changes have occurred. Expansion the inverted repeat (IR) regions at large single copy (LSC)/IRb small (SSC)/IR boundaries led to partial or entire duplications. Additionally, rearrangements...
Background and Purpose Endovascular recanalization therapy (ERT) is becoming increasingly important in the management of acute ischemic stroke (AIS). However, hospital volume threshold for optimal ERT remains unknown. We investigated relationship between risk-adjusted patient outcomes.Methods From National Health Insurance claims data Korea, 11,745 patients with AIS who underwent from July 2011 to June 2016 111 hospitals were selected. measured hospital’s outcomes, including 30-day...
The Araliaceae contain many valuable species in medicinal and industrial aspects. We performed intensive phylogenomics using the plastid genome (plastome) 45S nuclear ribosomal DNA sequences. A total of 66 plastome sequences were used, 13 which newly assembled this study, 12 from new sequences, one existing data. While plastomes showed conserved structure, phylogenetic reconstructions based on four different datasets revealed discordance within Asian Palmate group. divergence time estimation...
The recent DNA microarray technology enables us to understand a large number of gene expression profiling. has potential possibility comprehend mechanism multiple genes were related compounds which have toxicity in biological system. So, the toxicogenomics through this may be very powerful for understanding effect unknown toxic mechanisms We studied that hepatotoxin vivo system using and classified chemicals been well characterized. three compounds; 2 peroxisome proliferators: Clofibrate...
The tribe Hydrangeeae displays a unique, distinctive disjunct distribution encompassing East Asia, North America and Hawaii. Despite its complex trait variations polyphyletic nature, comprehensive phylogenomic biogeographical studies on this have been lacking. To address gap, we sequenced characterized 28 plastomes of Hydrangeeae. Our study highlights the highly conserved nature Hydrangeaceae chloroplast (cp) genomes in terms gene content arrangement. Notably, synapomorphic characteristics...
Huperzia javanica (Sw.) C. Y. Yang is a valuable medical herb used for treating Alzheimer's disease. Here, we described the complete chloroplast genome of H. using Illumina paired-end sequencing. The total length 154,415 bp, containing 119 unique genes, with 86 protein-coding 29 tRNA and 4 rRNA genes. gene content their order are consistent two previously reported genomes. overall GC 36.4%. topology our maximum-likelihood tree topologies found in previous studies, sister to clade serrata...
본 연구는 Hackman and Oldham의 직무특성이론에 근거하여 대학생을 대상으로 자원봉사활동 직무특성이 활동만족도와 지속의지에 미치는 효과를 분석하였다. 이를 위해 강원도내 6개 대학의 대학생 261명을 설문조사를 실시하여 자료를 연구 결과 대학생의 자원봉사참가율은 평균 71.6%로 나타났으며, 자원봉사활동의 직무특성과 활동만족도, 지속의지는 중간값 보다 낮은 수준으로 나타났다. 자원봉사 활동만족도에 직무특성의 효과에서는 기술다양성과 과업정체성, 피드백이 유의한 수준에서 영향을 것으로 나타났고, 대해서는 자율성을 제외한 기술다양성, 과업중요성, 피드백 모두가 또한 상관분석을 통해 활동만족도가 높으면 지속의지 역시 높아지는 것을 알 수 있다. 따라서 자원봉사관리자는 직무를 기초하여 설계(design)함으로써 의미충만감이나 책임감, 결과의식을 높여서 최종적으로는 자원봉사를 통한 동기부여와 성과 향상으로 이어져야 할 것이다. The purpose of this study...
본 연구는 대학생의 자원봉사활동 활성화를 위해 지속의지에 미치는 참여동기 및 인정보상 요인들을 분석하였다. 이를 참여경험이 있는 대학생 250명을 대상으로 1주일간 설문조사를 실시하고 결과를 참여동기는 이타적 동기와 이기적 동기로, 인정보상은 사회경제적 인정보상, 교육문화적 그리고 경제적 인정보상으로 범주화 하였다. 연구결과 동기가 혼재되어 있고, 대체로 사회심리적 높지만 수준은 낮게 나타났다. 다중회귀분석 결과 중 동기 모두, 중에서는 인정보상과 인정보상이 긍정적인 영향을 것으로 이러한 바탕으로 특히 강화를 중심으로 대학생들의 위한 정책적 실천적 함의를 논의하였다. The main objective of this study is to investigate the factor participation motivation, recognition and reward affecting continuance will university student volunteers. For...
Chloranthus fortunei (A. Gray) Solms-Laub. is a perennial herb in basal angiosperm family Chloranthaceae. Here, we reported the complete plastid genome of C. using Illumina short-read data. The total size was 157,063 bp length, containing 79 protein-coding genes, 30 tRNA and four rRNA genes. gene content order were consistent with previously genomes. overall GC 39.0%. In phylogenetic result, genus monophyletic divided into two subclades: japonicus+C. angustifolius+C. fortunei, henryi+C....
This study was carried out to investigate flora of Mt. Dosol(Yanggu-gun, Gangwon-do). The vascular plants were summarized as 510 taxa, including 89 families, 281 genera, 438 species, 3 subspecies, 61 varieties and 8 forms. Among the investigated 21 Korean endemic, 24 rare plants, 1 endangered plant 122 specially designated by Ministry Environment also included. naturalized 27 taxa. percent species urbanization index estimated 5.3% 8.4%, respectively. Usefulness taxa listed consists 201...