A5102016619- Cerebrovascular and Carotid Artery Diseases
- Acute Ischemic Stroke Management
- Intracranial Aneurysms: Treatment and Complications
- Vascular Malformations Diagnosis and Treatment
- Cerebral Venous Sinus Thrombosis
- Gastric Cancer Management and Outcomes
- Intracerebral and Subarachnoid Hemorrhage Research
- Advanced Neuroimaging Techniques and Applications
- Cardiovascular Health and Disease Prevention
- Moyamoya disease diagnosis and treatment
- Radiation Dose and Imaging
- MRI in cancer diagnosis
- Traumatic Brain Injury and Neurovascular Disturbances
- Vestibular and auditory disorders
- Parkinson's Disease Mechanisms and Treatments
- Neurological Disease Mechanisms and Treatments
- Cerebrospinal fluid and hydrocephalus
- Diagnosis and treatment of tuberculosis
- Venous Thromboembolism Diagnosis and Management
- Lymphadenopathy Diagnosis and Analysis
- Infectious Diseases and Tuberculosis
- Mycobacterium research and diagnosis
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Cardiac tumors and thrombi
- Colorectal Cancer Treatments and Studies
Pusan National University Yangsan Hospital
2016-2024
University Radiology
2021
Yonsei University
1990-2018
Severance Hospital
2018
Samsung Medical Center
2018
Sungkyunkwan University
2018
Gangnam Severance Hospital
2018
Kyungpook National University Hospital
2017
Indiana University Melvin and Bren Simon Comprehensive Cancer Center
2009
Seoul National University Hospital
1993-2009
In patients with posterior inferior cerebellar artery infarction (PICAI) or lateral medullary (LMI), the ipsilateral vertebral is often hypoplastic and therefore at an increased risk of ischaemic stroke.To investigate frequency clinical relevance (HVA) in stroke without territory normal healthy people.529 stroke, including (LMI PICAI), were classified according to their location (303 anterior circulation strokes (ACS) 226 (PCS)) by MRI. The HVA, defined as a diameter < = 2 mm magnetic...
Background and Purpose— Effective rescue treatment has not yet been suggested in patients with mechanical thrombectomy (MT) failure. This study aimed to test whether stenting (RS) improved clinical outcomes MT-failed patients. Methods— is a retrospective analysis of the cohorts 16 comprehensive stroke centers between September 2010 December 2015. We identified who underwent MT but failed recanalize intracranial internal carotid artery or middle cerebral M1 occlusion. Patients were...
Background and Purpose— Stent retriever (SR) thrombectomy has become the mainstay of treatment acute intracranial large artery occlusion. However, it is still not much known about optimal limit SR attempts for favorable outcome. We evaluated whether a specific number passes futile recanalization can be determined. Methods— Patients who were treated with as first endovascular modality their occlusion in anterior circulation retrospectively reviewed. The rate each pass was calculated....
Objective To characterise the time window in which endovascular thrombectomy (EVT) is associated with good outcome, and to test differential relationship between functional outcome onset-to-reperfusion (ORT), depending on collateral status. Methods This was a retrospective analysis of clinical imaging data 554 consecutive patients, who had recanalisation success by EVT for anterior circulation large artery occlusion, from prospectively maintained registries 16 comprehensive stroke centres...
We performed pretreatment brain MRIs in 25 patients with neurologically symptomatic Wilson9s disease (WD) and clinical MRI follow-up 16 of them. All revealed abnormalities, abnormal high-signal intensity (HSI) bilateral thalami being the most common (92%). HSI lesions brainstem (84%) basal ganglia (72%) were also common. Brain atrophy was present 88% patients. In period 5 to 24 months, during which treated D-penicillamine, both neurologic symptoms improved patients, but did not change.
Abstract Background Dilated perivascular spaces (DPVS), known as one of imaging markers in cerebral small vessel disease, may be found patients with moyamoya disease (MMD). However, little is about DPVS MMD. The purpose this study was to investigate the distribution pattern dPVS children and adults MMD determine whether it related steno-occlusive changes Methods scored basal ganglia (BG) white matter (WM) on T2-weighted imaging, using a validated 4-point semi-quantitative score. degree...
Plain and Gd-DTPA-enhanced MR images of the brain were obtained in 18 consecutive patients with meningitis (eight tuberculous, five bacterial, three viral, two fungal infections); compared CT scans. on a 2.0-T superconducting unit both T1- T2-weighted pulse sequences before injection T1-weighted sequence after Gd-DTPA (0.1 mmol/kg) all patients. In tuberculous meningitis, imaging depicted ischemia/infarct, hemorrhagic infarct basal ganglia, meningeal enhancement at either cistern or...
We present a case of patient in their 50s with spinal epidural arteriovenous fistula (SEDAVF) at L2 level intradural venous reflux. Initial transarterial embolization was attempted but failed due to vessel tortuosity and vasospasm. The second carried out percutaneous puncture the sac under cone-beam computed tomography angiography (CBCTA) guidance. Following complete obliteration fistula, resolution congestion significant improvement patient’s symptoms were achieved. This highlights utility...
There have been some reports on the use of intra-arterial tirofiban in ruptured intracranial aneurysms, but few studies reported 24 h intravenous infusion patients with subarachnoid hemorrhage.To present our experience infusion, form a monotherapy as well addition to tirofiban, prophylactic, and rescue management for thrombus who undergone embolization coils aneurysms.Between December 2008 January 2015, we retrospectively reviewed 249 aneurysms that were treated coiling at institutions. A...
Abstract BACKGROUND It remains controversial whether carotid artery stenting (CAS) is needed in cases of tandem cervical internal occlusion (cICAO) and intracranial large vessel (LVO). OBJECTIVE To investigate the efficacy safety CAS combination with endovascular thrombectomy (CAS-EVT) cICAO-LVO patients to compare its outcomes those EVT without (EVT-alone). METHODS We identified all who underwent for from prospectively maintained registries 17 stroke centers. Patients were classified into 2...
We report a 63 year-old woman who developed central pontine and extrapontine myelinolysis after rapid correction of hyponatremia. Lesions on brain MRI showed hypermetabolism 18FDG-PET scan in the early stage disease became hypometabolic follow-up scan. suggest that active microglia astrocytes are main cause increased glucose metabolism.
Systemic chemotherapy for gastric cancer is often associated with treatment-related toxicity, which particularly severe in patients a poor performance status. In this paper, we describe the first study to evaluate S-1 monotherapy as an option advanced who are not candidates combination due clinical condition. Fifty-two Eastern Cooperative Oncology Group (ECOG) scale 2-3, whose general condition had made use of impossible, were enrolled. was administered 30 second- or third-line therapy. The...
Backgroud The need for rescue treatment (RT) may differ depending on first-line modality (stent retriever (SR) or contact aspiration (CA)) in endovascular thrombectomy (EVT). We aimed to investigate whether the type of EVT was associated with RT. Methods identified all patients who underwent anterior circulation large-vessel occlusion from prospectively maintained registries 17 stroke centers. Patients were dichotomized into SR-first and CA-first. RT involved switching other device, balloon...
Background and Purpose Endovascular recanalization therapy (ERT) is becoming increasingly important in the management of acute ischemic stroke (AIS). However, hospital volume threshold for optimal ERT remains unknown. We investigated relationship between risk-adjusted patient outcomes.Methods From National Health Insurance claims data Korea, 11,745 patients with AIS who underwent from July 2011 to June 2016 111 hospitals were selected. measured hospital’s outcomes, including 30-day...
Abstract Background Cerebral venous and sinus thrombosis (CVST) can cause increased intracranial pressure, often leading to papilledema. In this study, we investigated the association between papilledema stasis on susceptibility weighted imaging (SWI) in CVST. Methods Patients with CVST 2008 2020 were reviewed. without fundoscopic examination or SWI excluded study. Venous was evaluated scored for each cerebral hemisphere: hemisphere divided into 5 regions according drainage territories...
Although CT has been used as a complementary diagnostic method for the preoperative diagnosis of thyroid cancer, it shortcomings substantial radiation exposure and use contrast material (CM). The purpose this article is to evaluate image quality performance 70-kVp with low volumes CM versus conventional 120-kVp protocol.Eighty patients referred were randomly divided into two groups (group A: 40 patients, 70 kVp, 60 mL CM; group B: 120 100 CM). Quantitative qualitative doses compared using...
Background The heterogeneous composition of substantia nigra (SN), including iron, nigrosome-1 substructure, and myelinated white matter, complicates the interpretation MRI signals. Purpose To investigate R2* quantitative susceptibility mapping (QSM) in SN subdivisions participants with Parkinson disease healthy control subjects. Materials Methods In this prospective study conducted from November 2018 to 2019, sex-matched subjects underwent 3-T MRI. QSM values were measured compared anterior...
Abstract This study assessed the image quality and diagnostic accuracy in determining disease activity of terminal ileum reduced-dose computed tomography enterography using model-based iterative reconstruction pediatric patients with Crohn’s (CD). Eighteen were prospectively enrolled allocated to standard-dose (SD) (RD) (CTE) groups ( n = 9 per group). Image quality, reader confidence interpreting bowel findings, active CD ileum, radiation dose evaluated. Objective did not show intergroup...
<h3>Abstract</h3> Resistance to BRAF and MEK inhibitors in BRAF<sup>V600E</sup> mutant melanomas remains a major obstacle that limits patient benefit. Microenvironment components including the extracellular matrix (ECM) can support tumor cell adaptation tolerance targeted therapies, however underlying mechanisms remain poorly understood. Here, we investigated process of matrix-mediated drug resistance (MM-DR) response inhibition melanoma. We demonstrate physical structural cues from...
Cancer invasion is induced by several proteolytic enzyme systems associated with the destruction of basement membrane and extracellular matrix. Urokinase-type plasminogen activator (uPA) inhibitor-1 (PAI-1) have been reported as prognostic factors in breast cancer patients activation regulated various such uPAR growth factors. Thus, we examined tissue levels urokinase-type receptor (uPAR) patients. Tissue were measured ELISA assay 268 The median mean values level 3.5 ng/mg cytosol protein...
Gastric tuberculosis accounts for approximately 2% of all cases gastrointestinal tuberculosis. Diagnosis gastric is challenging because it can present with various clinical, endoscopic, and radiologic features. Tuberculosis manifesting as a subepithelial tumor exceedingly rare; only several dozen have been reported. A 30-year-old male visited emergency room our hospital hematemesis melena. Abdominal CT revealed 2.5 cm mass in the antrum, endoscopy visible vessel at its center on antrum....