- Stroke Rehabilitation and Recovery
- Muscle activation and electromyography studies
- Motor Control and Adaptation
- Balance, Gait, and Falls Prevention
- Functional Brain Connectivity Studies
- Transcranial Magnetic Stimulation Studies
- Advanced Neuroimaging Techniques and Applications
- Cerebral Palsy and Movement Disorders
- Botulinum Toxin and Related Neurological Disorders
- Sports injuries and prevention
- Tactile and Sensory Interactions
- Bipolar Disorder and Treatment
- Injury Epidemiology and Prevention
- Advanced MRI Techniques and Applications
- Traumatic Brain Injury Research
- Musculoskeletal pain and rehabilitation
- Neurological disorders and treatments
- Mental Health Research Topics
- Electronic Packaging and Soldering Technologies
- Spinal Cord Injury Research
- Effects of Vibration on Health
- Action Observation and Synchronization
- Acute Ischemic Stroke Management
- Neural dynamics and brain function
- Diet and metabolism studies
South China Normal University
2024
International Collaboration On Repair Discoveries
2014-2023
University of Victoria
2014-2023
University of Alberta
2022
First Affiliated Hospital of Jinan University
2016-2018
Jinan University
2017
Peking University
2012
Pennsylvania State University
2011
General Electric (Austria)
2006
Purpose To investigate the whole-brain intrinsic functional connectivity patterns of patients with bipolar disorder (BD). Materials and Methods This prospective study was approved by research ethics committee, all participants provided informed consent. Thirty-seven nonmedicated BD II depression 37 healthy control underwent resting-state magnetic resonance (MR) imaging. Whole-brain analyzed using a graph theory approach: strength (FCS). Clinical state assessed 24-item Hamilton Depression...
Bipolar disorder (BD), particularly BD II, is frequently misdiagnosed as unipolar depression (UD), leading to inappropriate treatment and poor clinical outcomes. Although depressive symptoms may be expressed similarly in UD BD, the similarities differences architecture of brain functional networks between two disorders are still unknown. In this study, we hypothesized that II patients would show convergent divergent patterns disrupted topological organization connectome, especially default...
Training locomotor central pattern-generating networks (CPGs) through arm and leg cycling improves walking in chronic stroke. These outcomes are presumed to result from enhanced interlimb connectivity CPG function. The extent which rhythmic training activates for locomotion remains unclear was assessed by studying stroke participants before after 5 wk of training. Strength bilaterally via maximal voluntary isometric contractions the legs hands. Muscle activation during transfer treadmill...
Abstract Identifying brain differences and similarities between bipolar disorder (BD) major depressive (MDD) is necessary for increasing our understanding of the pathophysiology developing more effective treatments. However, features whole-brain intrinsic functional connectivity underlying BD MDD have not been directly compared. We collected resting-state fMRI data from 48 patients, 51 healthy subjects. constructed voxel-wise networks computed regional strength (FCS) using graph-theory...
Several recent studies have reported a strong association between the cerebellar structural and functional abnormalities psychiatric disorders. However, there are no to investigate possible changes in connectivity bipolar disorder. This study aimed examine whole-brain pattern of patients with remitted disorder II, particular cerebellum.A total 25 II controls underwent resting-state magnetic resonance imaging neuropsychological tests. Voxel-wise was analyzed using graph theory approach:...
Rhythmic arm and leg (A&L) movements share common elements of neural control. The extent to which A&L cycling training can lead adaptations transfer improved walking function remains untested. purpose this study was test the efficacy as a modality improve locomotor after stroke. Nineteen chronic stroke (>six months) participants were recruited performed 30 minutes three times week for five weeks. Changes in assessed with (1) clinical tests; (2) strength during isometric...
In this paper, we aim to investigate the effect of proprioceptive neuromuscular facilitation (PNF)-based rehabilitation for ankle plantar flexors spasticity by using a Robotic Ankle-foot Rehabilitation System (RARS). A modified robot-assisted system was proposed, and seven poststroke patients with hemiplegic spastic ankles participated in 3-month robotic PNF training. Their impaired sides were used as experimental group, while their unimpaired control group. intervention group started from...
Neural connections remain partially viable after stroke, and access to these residual provides a substrate for training-induced plasticity. The objective of this project was test if reflex excitability could be modified with arm leg (A & L) cycling training. Nineteen individuals chronic stroke (more than six months postlesion) performed 30 min A L training three times week five weeks. Changes in were inferred from modulation cutaneous stretch reflexes. multiple baseline (three pretests)...
Abnormalities in structural and functional brain connectivity have been increasingly reported patients with bipolar disorder (BD). However, alterations of remitted BD (RBD) between the cerebral hemispheres are still not well understood. This study was designed to analyze pattern interhemispheric whole during resting state. Twenty RBD 38 healthy controls (HC) underwent resting-state magnetic resonance imaging. The any pair symmetrical voxels (i.e., homotopy) measured by voxel-mirrored...
"Cross-education" is the increase in strength or functional performance of an untrained limb after unilateral training. A major limitation for clinical translation from injury includes knowledge on minimum time emergence crossed effects. Therefore, primary purpose was to characterize course bilateral changes during both "traditional" ( n = 11) and "daily" 8) handgrip training neurologically intact participants. Traditional included five sets maximal voluntary contractions 3 times/wk 6 wk...
The basic pattern of arm and leg movement during rhythmic locomotor tasks is supported by common central neural control from spinal supraspinal centers in neurologically intact participants. purpose this study was to test the hypothesis that following a cerebrovascular accident, shared systems interlimb cutaneous networks facilitating coordination persist across tasks. Twelve stroke participants (>6 months post CVA) performed (A&L) cycling using stationary ergometer walking on motorized...
Martial arts training has shown positive impacts on balance and physiological measurements. Further investigation of the contents feasibility an effective therapeutic assessment martial is needed in older adults, mainly for future applications real-world implementation. Sixteen adults (8 male, 8 female, age 59-90 years), with or without chronic conditions, participated a preliminary study using 5-weeks karate triple baseline control procedure. Group single subject data analyses were...