- Reproductive Biology and Fertility
- Reproductive Health and Technologies
- Assisted Reproductive Technology and Twin Pregnancy
- Ovarian function and disorders
- Sperm and Testicular Function
- Endometriosis Research and Treatment
- Reproductive System and Pregnancy
- Ovarian cancer diagnosis and treatment
- Uterine Myomas and Treatments
- BRCA gene mutations in cancer
- Pharmacological Effects and Toxicity Studies
- Menstrual Health and Disorders
- Family Dynamics and Relationships
- Pregnancy-related medical research
- Prenatal Screening and Diagnostics
- Epilepsy research and treatment
- Eating Disorders and Behaviors
- Reproductive biology and impacts on aquatic species
- Fetal and Pediatric Neurological Disorders
- Effects and risks of endocrine disrupting chemicals
- Pluripotent Stem Cells Research
- Genetic and Kidney Cyst Diseases
- Esophageal and GI Pathology
- Renal and related cancers
- Molecular Biology Techniques and Applications
WinnMed
2021-2025
Mayo Clinic
2021-2025
Artsakh State University
2024-2025
Mayo Clinic in Arizona
2020-2023
The University of Texas Southwestern Medical Center
2014-2020
Southwestern Medical Center
2014-2018
New York Medical College
2009-2012
CARE Fertility
2009
Westchester Medical Center
2009
Albert Einstein College of Medicine
2009
Purpose Germline mutations in BRCA genes are associated with breast and ovarian cancer susceptibility. Because infertility is risks, we hypothesized that the gene may be low response to fertility treatments. Methods We performed stimulation 126 women by using letrozole gonadotropins for purpose of preservation embryo or oocyte cryopreservation. As surrogates reserve, yield incidence were compared according mutation status. Results Of 82 who met inclusion criteria, 47 (57%) had undergone...
There is a broad phenotypic spectrum of monogenic polycystic kidney diseases (PKDs). These disorders often involve cilia-related genes and lead to the development fluid-filled cysts eventual function decline failure. Preimplantation genetic testing for (PGT-M) has moved into clinical realm. It allows prospective parents avoid passing on heritable their children, including PKD. The PGT-M process involves embryo generation through in vitro fertilization, with subsequent embryos selective...
MicroRNAs (miRs) are small molecules important for regulation of transcription and translation. The objective was to identify hormonally-regulated miRs in human endometrial stromal cells determine the impact endocrine disruptor, bisphenol A (BPA), on those miRs. miR microarray analysis multiple confirmatory cell preparations treated with 17β-estradiol (E2) BPA altered miR-27b, let-7c, let-7e, miR-181b. Further, decidualization downregulated miR-27b. VEGFB VEGFC were validated as targets...
To report a successful case of magnetic resonance imaging (MRI)-guided oocyte retrieval in patient with challenging pelvic anatomy, extensive adhesive disease, and diminished ovarian reserve, necessitated by the inability to visualize ovaries using transvaginal or transabdominal ultrasound. Case report. A 33-year-old nulligravid woman history ulcerative colitis, multiple abdominal surgeries, significant disease. Controlled stimulation was initiated gonadotropin-releasing hormone antagonist...
Abstract The objective of this study was to determine seizure control in women with epilepsy (WWE) undergoing assisted reproductive technology (ART). Through retrospective chart review, WWE ART were identified. Demographics and details regarding type, control, procedures extracted. Seizure frequency prior during compared. We identified 12 WWE, who underwent 29 embryo transfers, resulting 16 pregnancies 10 live births. Nine seizure‐free at least 2 years before fertility treatment, including...
Abstract Background Although a shared experience throughout the world, menstrual symptomatology is underreported and often misunderstood, by both individuals who menstruate their providers. This study aimed to investigate cycle, including frequency of symptoms reported for each phase cycle relationship between symptoms. Methods included self-reported information during ovulatory cycles in mobile application users. Symptom was described overall, phase, day. Relationships were examined through...
It has been reported that endometriosis may be associated with progesterone resistance impacting its treatment progestins. Danazol (D), an androgenic compound, had approved for medical of whereas D's side effects limited wide spread acceptance. Androgenic compounds have also implicated in induction endometrial atrophy yet the mechanisms androgen on endometrium not well studied. We hypothesize androgens promote their via modulation receptor (PR) expression. evaluated selected PR expression by...
<title>Abstract</title> <bold>Background</bold> Although a shared experience throughout the world, menstrual symptomatology is underreported and often misunderstood, by both individuals who menstruate their providers. This study aimed to investigate cycle, including frequency of symptoms reported for each phase cycle relationship between symptoms. <bold>Methods</bold> included self-reported information during ovulatory cycles in mobile application users. Symptom was described overall, phase,...
To assess the oocyte to blastocyst attrition rate in patients undergoing vitro fertilization (IVF) with male factor infertility (MFI) using testicular sperm. Retrospective cohort study. Patients who underwent IVF sperm for MFI between January 1, 2017, and March 23, 2023. Testicular extraction (TESE) intracytoplasmic injection. The blastulation outcomes. A total of 120 cycles were identified. For comparison, 122 unexplained had normal semen analysis used ejaculated injection reviewed as a...