- Gut microbiota and health
- Probiotics and Fermented Foods
- Microbial Metabolites in Food Biotechnology
- Infant Nutrition and Health
- Diet and metabolism studies
- Clostridium difficile and Clostridium perfringens research
- Digestive system and related health
- Nutritional Studies and Diet
- Infant Health and Development
- Genomics and Phylogenetic Studies
- Urinary Tract Infections Management
- Gastrointestinal motility and disorders
- Pediatric health and respiratory diseases
- Viral gastroenteritis research and epidemiology
- Nutrition, Genetics, and Disease
- Microscopic Colitis
- Nosocomial Infections in ICU
- Health and Lifestyle Studies
- Neonatal and Maternal Infections
- Enterobacteriaceae and Cronobacter Research
- Food Allergy and Anaphylaxis Research
- Clinical Nutrition and Gastroenterology
- Antibiotic Resistance in Bacteria
- Dietary Effects on Health
- Enzyme Production and Characterization
Instituto de Productos Lácteos de Asturias
2016-2025
Consejo Superior de Investigaciones Científicas
2015-2024
Instituto de Investigación Sanitaria del Principado de Asturias
2018-2024
Gobierno del Principado de Asturias
2022
University of Turku
2004-2014
Rafael Advanced Defense Systems (Israel)
2014
Paracelsus Medical University
2013
Instituto de Agroquímica y Tecnología de Alimentos
2011
Universidade de Vigo
2011
Cambridge University Press
2011
Background The human gastrointestinal tract (GIT) represents one of the most densely populated microbial ecosystems studied to date. Although this consortium has been recognized have a crucial impact on health, its precise composition is still subject intense investigation. Among GIT microbiota, bifidobacteria represent an important commensal group, being among first colonizers gut. However, prevalence and diversity members genus Bifidobacterium in infant intestinal microbiota not yet fully...
Probiotics are live microorganisms which when administered in adequate amounts confer a health benefit on the host. The main probiotic bacteria strains belonging to genera Lactobacillus and Bifidobacterium, although other representatives, such as Bacillus or Escherichia coli strains, have also been used. Bifidobacterium two common inhabitants of human intestinal microbiota. Also, some species used food fermentation processes starters, adjunct cultures industry. With exceptions, antibiotic...
ABSTRACT Systemic lupus erythematosus (SLE) is the prototypical systemic autoimmune disease in humans and characterized by presence of hyperactive immune cells aberrant antibody responses to nuclear cytoplasmic antigens, including characteristic anti–double-stranded DNA antibodies. We performed a cross-sectional study order determine if an SLE-associated gut dysbiosis exists patients without active disease. A group 20 SLE remission, for which there was strict inclusion exclusion criteria,...
Microbial colonization of the infant gut is essential for development intestine and immune system. The profile intestinal microbiota in full-term, vaginally delivered, breast-fed considered as ideally healthy. However, preterm infants this process challenging, mainly because organ immaturity, antibiotics use, hospital stay. To assist a proper these infants, detailed knowledge process, differences from that full-term needed. We assessed establishment its metabolic activity neonates (n = 21)...
Cross-feeding is an important metabolic interaction mechanism of bacterial groups inhabiting the human colon and includes features such as utilization acetate by butyrate-producing bacteria may occur between Bifidobacterium Faecalibacterium genera. In this study, we assessed different carbon sources (glucose, starch, inulin fructooligosaccharides) strains both genera selected best suited combinations for evidencing cross-feeding phenomenon. Co-cultures adolescentis L2–32 with prausnitzii...
Assessing the distribution of 16S rRNA gene sequences within a biological sample represents current state-of-the-art for determination human gut microbiota composition. Advances in dissecting microbial biodiversity this ecosystem have very much been dependent on development novel high-throughput DNA sequencing technologies, like Ion Torrent. However, precise representation bacterial community may be affected by protocols used extraction as well PCR primers employed amplification reaction....
Disturbances in the early establishment of intestinal microbiota may produce important implications for infant's health and risk disease later on. Different perinatal conditions be affecting development gut microbiota. Some them, such as delivery mode or feeding habits, have been extensively assessed whereas others remain to studied, being critical identify their impact on and, if any, minimize it. Antibiotics are among drugs most frequently used life, use intrapartum antimicrobial...
Short chain fatty acids (SCFA) are the main bacterial products of catabolism carbohydrates and proteins in gut, their role is essential host-microbiota interactions. Acetic, propionic butyric major SCFA produced they have been extensively studied. In contrast, branched short (BCFA), mainly isovaleric isobutyric acids, less amounts fecal levels different human groups, intestinal microbial producing populations, influence on health insufficiently known. They proposed as markers protein...
OPINION article Front. Microbiol., 07 March 2017Sec. Food Microbiology Volume 8 - 2017 | https://doi.org/10.3389/fmicb.2017.00376
The fecal microbiota plays an important role in human health, and alterations the microbiota-host interaction seem to be involved ageing process. Therefore, it is of interest develop strategies for promoting a balanced old age order prevent physiological immune decline associated with age. However, specific changes transition from adulthood senescence are not yet well understood. Here we assessed levels some intestinal microorganisms short chain fatty acids (SCFAs) across different...
The sources and the impact of maternal bacteria on initial inoculum intestinal microflora newborn infants remain elusive.To assess association between breast-milk fecal bifidobacteria infants' bifidobacteria.Sixty-one mother-infant pairs were included, special emphasis being placed allergic status. Bifidobacteria analysed by a direct PCR method in samples from mothers at 30-35 weeks gestation 1 month age post-partum.Fecal Bifidobacterium adolescentis bifidum colonization frequencies counts...
<i>Background:</i> The establishment of gut microbiota is a stepwise process contributing to development and maturation the immune system. Aberrant at an early age may predispose disease later in life. Breast-fed infants harbor characteristic intestinal dominated by bifidobacteria. <i>Objectives:</i> To assess, using molecular techniques (PCR), whether human milk contains bifidobacteria determine bifidobacterial species present. <i>Methods:</i> presence...