- Probiotics and Fermented Foods
- Gut microbiota and health
- Infant Nutrition and Health
- Infant Health and Development
- Food Allergy and Anaphylaxis Research
- Digestive system and related health
- Viral gastroenteritis research and epidemiology
- Pediatric health and respiratory diseases
- Asthma and respiratory diseases
- Dermatology and Skin Diseases
- Diet and metabolism studies
- Birth, Development, and Health
- Eosinophilic Esophagitis
- Clostridium difficile and Clostridium perfringens research
- Breastfeeding Practices and Influences
- Microbial Metabolites in Food Biotechnology
- Clinical Nutrition and Gastroenterology
- Allergic Rhinitis and Sensitization
- Gestational Diabetes Research and Management
- Fatty Acid Research and Health
- Obesity, Physical Activity, Diet
- Neonatal Respiratory Health Research
- Child Nutrition and Water Access
- Child Nutrition and Feeding Issues
- Gastrointestinal motility and disorders
Turku University Hospital
2016-2025
University of Turku
2016-2025
Pediatrics and Genetics
2007-2017
Office of Adolescent Health
2016
Institute of Clinical Research
2013
Tampere University
1992-2012
Tampere University Hospital
1989-2012
Cambridge University Press
2010-2011
New York University Press
2010-2011
Royal Children's Hospital
2007-2009
Background Over the last two decades incidence of allergic diseases has increased in industrialized countries, and consequently new approaches have to be explored. Objective The potential probiotics control inflammation at an early age was assessed a randomized double‐blind placebo‐controlled study. Methods A total 27 infants, mean 4.6 months, who manifested atopic eczema during exclusive breast‐feeding had no exposure any infant or substitute formula were weaned probiotic‐supplemented,...
Abstract Interaction with intestinal microbes in infancy has a profound impact on health and disease later life through programming of immune metabolic pathways. We collected maternal faeces, placenta, amniotic fluid, colostrum, meconium infant faeces samples from 15 mother-infant pairs an effort to rigorously investigate prenatal neonatal microbial transfer gut colonisation. To ensure sterile sampling, only deliveries at full term by elective caesarean section were studied. Microbiota...
Fluorescence in situ hybridization and real-time PCR analysis targeting the 16S rRNA gene of Akkermansia muciniphila were performed to determine its presence human intestinal tract. These techniques revealed that an A. muciniphila-like bacterium is a common member tract colonization starts early life develops within year level close observed adults (10(8) cells/g) but decreases (P < 0.05) elderly.
Abstract The infant gut microbiota has a high abundance of antibiotic resistance genes (ARGs) compared to adults, even in the absence exposure. Here we study potential sources ARGs by performing metagenomic sequencing breast milk, as well and maternal microbiomes. We find that fecal ARG mobile genetic element (MGE) profiles infants are more similar those their own mothers than unrelated mothers. MGEs mothers’ milk also shared with infants. Termination breastfeeding intrapartum prophylaxis...
Objectives. Antimicrobial treatment may disturb the colonization resistance of gastrointestinal microflora, which induce clinical symptoms, most commonly diarrhea. The severity antibiotic-associated diarrhea range from a brief, self-limiting disease to devastating with electrolyte disturbances, dehydration, crampy abdominal pain, pseudomembranous colitis, toxic megacolon, or even death. incidence in children receiving single antimicrobial is unclear. In addition more critical use...
Oral Lactobacillus rhamnosus GG ingestion for 5 days to 4 weeks has been shown alleviate clinical symptoms of gastrointestinal inflammation and atopic dermatitis. To determine whether oral may act by generating immunosuppressive mediator in children. (ATCC 53103) at a daily dose 2 × 10 cfu was added the diets nine children (mean age, 21 months) with Blood faecal samples were collected before supplementation early (2 weeks) late stage (4 8 from beginning). The concentrations interleukin‐6...