A5102958089- Phagocytosis and Immune Regulation
- Extracellular vesicles in disease
- Photodynamic Therapy Research Studies
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Nanoplatforms for cancer theranostics
- Nanoparticle-Based Drug Delivery
China Pharmaceutical University
2014-2023
Abstract Atherosclerosis is a progressive inflammatory disease characterised by excessive lipid accumulation and cell infiltration the basis of most cardiovascular diseases peripheral arterial diseases. Therefore, an effectively targeted delivery system urgently needed to deliver ferroptosis‐specific inhibitors site plaque microenvironment. Inspired fact that neutrophils can be recruited plaques under action adhesion molecules chemokines, authors developed neutrophil membrane hybrid liposome...
In order to improve Doxorubicin (Dox) targeting in vivo and reduce toxicity, use the ligand 2-deoxy-aminoglucose (2DG) modify form a new anti-tumor drug. The products was charactered by <sup>1</sup>H-NMR, MS, research near-infrared imaging. Compared with Dox , product treating MCF-7 U87MG cells shows higher antitumor activity vitro MTT assay. conclusion, modified effectively enhance pharmacodynamics contrast Dox, it would be potential therapeutic drug for cancer.