- Pelvic floor disorders treatments
- Urological Disorders and Treatments
- Hernia repair and management
- Pregnancy-related medical research
- Pelvic and Acetabular Injuries
- IgG4-Related and Inflammatory Diseases
- Neuroendocrine Tumor Research Advances
- Eosinophilic Disorders and Syndromes
University of California, San Diego
2021-2023
National University Hospital
2007
Pelvic floor disorders, including pelvic organ prolapse and urinary fecal incontinence, affect millions of women globally represent a major public health concern. muscle (PFM) dysfunction has been identified as one the leading risk factors for development these morbid conditions. Childbirth, specifically vaginal delivery, recognized most important potentially modifiable factor PFM injury; however, precise mechanisms after parturition remain elusive. In this study, we demonstrated that PFMs...
Abstract Pelvic floor disorders, which include pelvic organ prolapse, and urinary fecal incontinence, affect millions of women globally represent a major public health concern. muscle (PFM) dysfunction has been identified as one the leading risk factors for development these morbid conditions. Even though childbirth, specifically vaginal delivery, long recognized most important potentially modifiable factor PFM injury, precise mechanisms following childbirth remain elusive. In this study we...
BackgroundPelvic floor muscle injury is a common consequence of vaginal childbirth. Nonsteroidal anti-inflammatory drugs are widely used postpartum analgesics. Multiple studies have reported negative effects these on limb regeneration, but their impact pelvic recovery following birth has not been explored.ObjectiveUsing validated rat model, we assessed the nonsteroidal drug acute and longer-term simulated injury.Study DesignThree-month old Sprague Dawley rats were randomly assigned to...