A5055666265- Ovarian function and disorders
- Reproductive Biology and Fertility
- Reproductive System and Pregnancy
- Lysosomal Storage Disorders Research
- Endometriosis Research and Treatment
- Metabolism and Genetic Disorders
- Genetics and Neurodevelopmental Disorders
- Gynecological conditions and treatments
- Assisted Reproductive Technology and Twin Pregnancy
- Genetic Syndromes and Imprinting
- Growth Hormone and Insulin-like Growth Factors
- Genomics and Rare Diseases
- Neurogenetic and Muscular Disorders Research
- Trypanosoma species research and implications
- Connective tissue disorders research
- Neonatal Health and Biochemistry
- Sexual Differentiation and Disorders
- Reproductive Health and Contraception
- Folate and B Vitamins Research
- Birth, Development, and Health
- Biochemical and Molecular Research
- Cellular transport and secretion
- Ectopic Pregnancy Diagnosis and Management
- Glycogen Storage Diseases and Myoclonus
- Sexual function and dysfunction studies
Shahid Beheshti University of Medical Sciences
2016-2025
European Gravitational Observatory
2024
University of Messina
2024
Masih Daneshvari Hospital
2010-2012
Shahid Beheshti University
2008-2011
Boston Children's Hospital
2010
Mofid University
2009
Taleghani General Hospital
2008
Endometrium is one of the main factors in pregnancy.During assisted reproductive technology (ART) treatments, some cycles are cancelled due to inadequate endometrial growth.This study was conducted evaluate effectiveness platelet-rich plasma (PRP) treatment thin endometrium.Ten patients with history growth frozen-thawed embryo transfer (FET) were recruited into study.Intrauterine infusion PRP performed.Endometrial thickness assessed.Chemical and clinical pregnancies reported.In all patients,...
Polycystic Ovary Syndrome (PCOS) is a complex endocrine disorder that affects large proportion of women. Due to its heterogeneity, the best diagnostic strategy has been matter contention. Since 1990 scientific societies in field human reproduction have tried define pivotal criteria for diagnosis PCOS. The consensus Rotterdam included presence hyperandrogenism, oligo/anovulation, and polycystic ovarian morphology (PCOM), now updated evidence based 2018 2023 International Guideline endorsed by...
The recommended composition of a hypocaloric diet for obese women with polycystic ovary syndrome (PCOS) is unclear. aim this study was to investigate the effects high-protein, low-glycemic-load compared conventional on reproductive hormones, inflammatory markers, lipids, glucose, and insulin levels in PCOS.A total 60 overweight PCOS who did not use insulin-sensitizing agents were recruited randomly assigned 1 2 groups single-blind clinical trial. included (CHCD) (15% daily energy from...
Repeated implantation failure (RIF) is a major challenge in reproductive medicine and despite several methods that have been described for management, there little consensus on the most effective one.This study was conducted to evaluate effectiveness of platelet-rich plasma improvement pregnancy rate RIF patients.Twenty women with history who were candidates frozen-thawed embryo transfer recruited this study. Intrauterine infusion 0.5 ml contained platelet 4-5 times more than peripheral...
Repeated implantation failure is a major challenge in reproductive medicine and despite several methods that have been described for management, there little consensus on which the most effective. This study was conducted to evaluate effectiveness of autologous platelet-rich plasma improving pregnancy rate repeated failure. Between 2016 2017, total 138 patients who failed conceive after 3 or more embryo transfers with high quality embryos candidate frozen-thawed transfer were assessed...
Adequate endometrial growth is principal for implantation and pregnancy. Thin endometrium associated with lower pregnancy rate in assisted reproductive technology. Some frozen-thawed embryo transfer cycles are cancelled due to inadequate growth.To assess the effectiveness of autologous platelet-rich plasma (PRP) intrauterine infusion treatment thin endometrium.A total 72 patients who had a history cycle ( < 7mm) were assessed eligibility enter study between 2016 2017. Twelve excluded...
Abstract No data exist on the population prevalence of, or risk factors for, human papillomavirus (HPV) infection in Iran Middle East. Cervical specimens were obtained from 825 married women aged 18–59 years general of Tehran, and 45 locally diagnosed invasive cervical cancers (ICC) according to standardized protocol International Agency for Research Cancer HPV Prevalence Surveys. was detected genotyped using a GP5+/6+ PCR‐based assay. 7.8% (95% confidence interval: 6.0–9.8) (5.1% high‐risk...
Constitutional delay of growth and puberty (CDGP) with short stature is one the most common problems in pediatrics. We compared effects letrozole that oxandrolone on predicted adult height (PAH), puberty, bone mineral density, serum insulin-like factor 1 (IGF-1) blood lipoproteins.In a prospective, double-blind, randomized, placebo-controlled clinical trial, 91 CDGP boys (12.6-14.6 years old) were treated (2.5 mg/day), or placebo, at outpatient pediatric endocrine clinic Mofid Children's...
Recurrent pregnancy loss (RPL) is a fertility problem for which no exact mechanism of abortion or efficient treatment has been described. This study was conducted between 2018 and 2019 to investigate the effectiveness autologous platelet-rich plasma (PRP) in improving live birth rate women with RPL who required vitro fertilization (IVF).A total 63 patients at least two previous losses specific cause detected were included randomly assigned into groups (PRP control). Intrauterine infusion 0.5...
Abstract Aim: The aim of this study was to evaluate the effect oral N‐acetylcysteine (NAC) administration as an adjuvant clomiphene citrate (CC) on induction ovulation outcomes in patients with polycystic ovary syndrome (PCOS). Material and Methods: In placebo‐controlled double‐blind randomized clinical trial, 180 PCOS infertile were randomly divided into two groups for ovulation. Patients group 1 received CC 100 mg/d plus NAC 1.2 g/d 2 placebo 5 days starting at day 3 cycle. On 12th...
The aim of the present study was to compare efficacy, tolerability and patients' satisfaction after use oral dydrogesterone with vaginal micronized progesterone for luteal-phase support (LPS) among infertile women undergoing in vitro fertilization (IVF). A total 210 (aged 20-40 years old) a history infertility, who underwent controlled ovarian stimulation fresh intra-cytoplasmic sperm injection-embryo transfer cycles, were included study. Consequently, they randomized receive LPS 20 mg twice...
Knobloch Syndrome (KS) is a rare genetic disorder characterized by ocular abnormalities and central nervous system (CNS) defects, which are attributed to collagenopathy. The primary gene implicated in KS <em>COL18A1</em>, encodes the alpha chain of type XVIII collagen. This collagen functions as proteoglycan, predominantly located basement membrane human tissues. study examined an Iranian female presenting with symptoms horizontal nystagmus, strabismus, suspected vision loss,...
Severe osteogenesis imperfecta (OI) is a disorder characterized by osteopenia, frequent fractures, progressive deformity, loss of mobility, and chronic bone pain. There has been no effective therapy for the until recently. The main objective this study was to determine efficacy safety pamidronate in improving mineralization reducing fracture incidence imperfecta.Intravenous administered 64 children (from 21 months 10 years old) with severe OI, 1 mg/kg single daily dose 3 sequential days at...
In this study, we evaluated the incidence of apoptosis at ultrastructural levels and expression some apoptosis-related genes in vitrified human ovarian tissue just after warming.Human biopsies from 23 women caesarean section were transported to laboratory within 2 hours, then they cut into small pieces. Some pieces warmed other samples considered as control. Apoptosis was assessed by a transmission electron microscope also molecular analysis pro-apoptotic (Fas, FasL, Bax, p53, caspase8,...
Platelet-rich plasma (PRP) has been widely used to treat women with infertility but is rarely in men similar conditions. Several studies have shown that PRP contains a large spectrum of growth factors may benefit sperm, the application sperm processing techniques not examined completely yet. This study aimed investigate effect adding supplementation human semen incubation and swim-up processes evaluate parameters after addition. The current experimental included 80 samples. samples were...
Woodhouse-Sakati syndrome (WSS) is a rare autosomal recessive neuroendocrine disorder characterized by variety of endocrine and neurological involvement, including extrapyramidal symptoms intellectual disability. This report presents five Iranian patients with WSS their genetic characterizations, also reporting the first patient to undergo Deep Brain Stimulation (DBS). We highlight mutations in DCAF17 gene presenting variable features WSS, symptom onset early adolescence. Whole exome...