A5004895583- Effects and risks of endocrine disrupting chemicals
- Heavy Metal Exposure and Toxicity
- Pregnancy and preeclampsia studies
- Neuroscience and Neuropharmacology Research
- Birth, Development, and Health
- Pregnancy and Medication Impact
- Air Quality and Health Impacts
- Neuroinflammation and Neurodegeneration Mechanisms
- Preterm Birth and Chorioamnionitis
- Gut microbiota and health
- Estrogen and related hormone effects
- Antibiotic Use and Resistance
- Toxic Organic Pollutants Impact
- Chemical Analysis and Environmental Impact
- Tryptophan and brain disorders
- Stress Responses and Cortisol
- Neonatal and fetal brain pathology
- Trace Elements in Health
- Aluminum toxicity and tolerance in plants and animals
- Schizophrenia research and treatment
- Selenium in Biological Systems
- Carcinogens and Genotoxicity Assessment
- Metabolomics and Mass Spectrometry Studies
- Arsenic contamination and mitigation
- Antibiotics Pharmacokinetics and Efficacy
Anhui Medical University
2016-2025
Second Hospital of Anhui Medical University
2025
Ministry of Education of the People's Republic of China
2022-2025
University of Science and Technology of China
2007-2015
Prenatal exposure to organophosphate esters (OPEs) and phthalic acid (PAEs) is ubiquitous among pregnant individuals. However, research exploring the relationship between prenatal co-exposure OPEs PAEs childhood insulin function remains limited. In this study, utilizing data from 2,246 maternal-fetal dyads in Ma'anshan Birth Cohort, associations action were analyzed. Repeated measures of tris (2-chloroethyl) phosphate, six OPE metabolites, seven PAE metabolites collected maternal urine....
The relationship between prenatal arsenic exposure at low levels and poor development in children, especially regard to neurodevelopment, has aroused several concerns, but the conclusions have been inconsistent. It still remains unclear whether such adverse effect is associated with a specific profile of developing brain early life. To investigate association utero children’s behaviour, we performed large prospective birth cohort study including 2315 mother-infant pairs Anhui Province,...
Although studies have reported an increased risk for mood disorders in Hashimoto's thyroiditis (HT) patients even the euthyroid state, mechanisms involved remain unclear. Neuroinflammation may play a key role etiology of humans and behavioral disturbances rodents. Therefore, this study established HT model mice investigated whether itself was capable triggering neuroinflammation accompanied by emotional alterations.Experimental induced immunizing NOD with thyroglobulin adjuvant twice. Four...
A few studies have reported phthalate exposure as a risk factor for depressive symptoms, but the results been inconsistent. Whether chronic inflammation mediates relationship between phthalates (PAEs) and symptoms remains unclear. In this study, we establish mediating models of inflammatory factors explore role in association PAEs symptoms.The sample included 989 participants from Study on Health Environment Elderly Lu'an City, Anhui Province. Geriatric depression scale (GDS-30) was used to...
Experimental and epidemiological studies have linked antibiotics use to gut dysbiosis-mediated risk of chronic metabolic diseases. However, whether adiposity is antibiotic exposure in elderly remains inadequately understood. To investigate the association between internal by using a biomonitoring method. We included 990 participants (≥ 60 years) from baseline survey Cohort Elderly Health Environment Controllable Factors Lu'an city, China, June September 2016. Forty-five two metabolites urine...
Rhizoma drynariae total flavonoids (RDTF) are extracted from Drynaria fortunei J. Sm (D. fortunei), which was a Chinese herb commonly used to treat fractures and bruises. Modern pharmacological studies indicate have anti-inflammatory effect in clinical practice. However, its active ingredients the mechanisms of action far clear. The present study aims determine whether RDTF can protect against intervertebral disc degeneration rat cervical model investigate associated molecular mechanisms....
The potential maternal and neonatal thyrotoxicity associated with exposure to arsenic during pregnancy is very limited unclear.This study aimed examine the associations between levels in cord serum thyroid hormone parameters a prospective birth cohort study.The including 2089 mother-neonate pairs was based upon Ma'an Shan China. variables first, second third trimester average level level. Maternal TSH FT4 were determined using electrochemiluminescence immunoassay Cobas Elecsys 411. Linear...