The primate foveola, with its high cone density and magnified cortical representation, is exquisitely specialized for high-resolution spatial vision. However, uncovering the wiring of retinal circuitry responsible this performance has been challenging due to difficulty in recording receptive fields foveal ganglion cells (RGCs) vivo. In study, we use adaptive optics scanning laser ophthalmoscopy (AOSLO) image calcium responses RGCs living primate, a stable, precision visual stimulus that...

Human astroviruses (HAstVs) are a leading cause of viral diarrhea in young children, the immunocompromised, and elderly. There no vaccines or antiviral therapies against HAstV disease. Several lines evidence point to presence protective antibodies healthy adults as mechanism governing protection reinfection by HAstV. However, development anti-HAstV is hampered gap knowledge antibody epitopes on capsid surface. Here, we report structure spike domain bound neutralizing monoclonal PL-2. The...

Crohn's disease (CD) often necessitates surgical intervention, with temporary stoma creation after intestinal resection (IR) being a crucial decision. This study aimed to construct novel models based on machine learning (ML) predict formation IR for CD. Patient data who underwent CD at our center between July 2017 and March 2023 were collected inclusion in this retrospective study. Eligible patients randomly divided into training validation cohorts. Feature selection was executed using the...

To prospectively investigate the feasibility of shear wave elastography (SWE) as a new quantitative and objective method for evaluating stiffness gastrocnemius medialis (GM) muscle during passive stretching in patients with Parkinson's disease (PD). SWE GM was performed 28 PD [13 female 15 male; mean age ± standard deviation (SD): 63.0 8.5 years] 12 healthy controls (5 7 SD: 59.3 6.4 years) ankle rotation. A Young's modulus-ankle angle curve constructed. The slack baseline modulus (E0) were...

Ultrasound and photoacoustic imaging are emerging as powerful tools to study brain structures functions. The skull introduces significant distortion attenuation of the ultrasound signals deteriorating image quality. For biological studies employing rodents, craniotomy is often times performed enhance qualities. However, unsuitable for longitudinal studies, where a long-term cranial window needed prevent repeated surgeries. Here, we propose mouse model eliminate sound blockage by top portion...

To evaluate the value of intraoperative B-mode ultrasound and shear wave elastography (SWE) in differentiating low-grade high-grade gliomas.A total 172 patients with glioma were examined by to obtain a tumor sonogram. Intraoperative SWE was performed on 52 Young's modulus values peritumor tissue tissue, differences conventional signs gliomas different grades then compared. The diagnostic performance grading assessed receiver operating characteristic (ROC) curve analysis, intra- interobserver...

Retroperitoneal sarcoma is a rare disease with poor prognosis. The aim of this study was to investigate the prognostic factors disease.Between January 1988 and December 2003, 132 patients retroperitoneal were surgically treated in our hospital, 79 them followed up for 1 - 122 months (median: 19 months). Their clinicopathological data including tumor size, histological subtype, grade resection margin status, studied. Kaplan-Meier method log-rank test used analyze disease-specific survival...

AIM:To e va l u a t p r o ra i v d b -b n enteroscopy for determining bleeding lesions of small intestine, thus directing selective surgical intervention. METHODS:We retrospectively reviewed 56 patients who underwent double-balloon to localize intestinal prior intervention, and compared enteroscopic findings with those intraoperation determine the accuracy in identifying localizing sites bleeding.RESULTS: Double-balloon was performed all 30-mo period.A possible site blood loss identified 54...

[Purpose] The purpose of this study was to evaluate whether neuromuscular joint facilitation (NJF) training is superior NJF distal resistance at improving the ROM and proprioceptive acuity neck. [Subjects] 10 healthy subjects (8 males, 2 females) participated in study. [Methods] participants were allocated three groups: control group, group. A miniature wireless motion recorder used record maximum cervical range position error (JPE) before after interventions. interventions tested on...

Photoacoustic (PA, or optoacoustic, OA) mesoscopy is a powerful tool for mouse cerebral imaging, which offers high resolution three-dimensional (3D) images with optical absorption contrast inside the optically turbid brain. The image quality of PA mesoscope relies on ultrasonic transducer detects signals. An all-optical ultrasound sensor based Fabry-Pérot (FP) polymer cavity has following advantages: broadband frequency response, wide angular coverage and small footprint. Here, we present 3D...

[Purpose] Older adults requiring long-term care have a higher rate of falls than older who do not. This study aimed to examine the relationship between and fear falling their characteristics from perspective based on sub-item in Modified Falls Efficacy Scale. [Participants Methods] included 51 were certified as needing care. Fear was measured using The Scale basic information, such cognitive function, history falls, level required, age, collected analyzed fall or non-fall groups. [Results]...

[Purpose] The shoulder joint has a very unstable structure yet significantly wide range of motion. Weakness the muscles around may cause subluxation. This study aimed to determine changes in supraspinatus muscle thickness between different abduction angles using ultrasonography and compare differences affected unaffected sides depending on [Participants Methods] Forty hemiplegic patients with stroke were recruited (20 20 without subluxation). Using ultrasonography, we measured at three...

Although minimally invasive surgery is becoming more commonly applied for ileostomy reversal (IR), there have been relatively few studies of IR patients with Crohn's disease (CD). It therefore important to evaluate the potential benefits and risks laparoscopy CD.To compare safety, feasibility, short-term long-term outcomes laparoscopic (LIR) vs open (OIR) treatment CD.The baseline characteristics, operative data, (30-d) CD who underwent LIR OIR at our institution between January 2017 2020...

[Purpose] This study aimed to evaluate the reliability of intraclass correlation coefficient (ICC) in measuring deltoid muscle thickness (DMT) at different angles, acromion-humeral distance (AHD), and acromion nodule tuberosity (ALT) a resting position stroke patients using ultrasonography. [Participants Methods] We included 40 patients. During measurement parameters by ultrasonography, we measured on both sides three test angles (0°, 30°, 60° abduction) AHD ALT 0° angle. The ICC was used...

Objective To evaluate the accuracy of cone-beam breast CT (CBBCT) on tumor sizing in patients with invasive carcinoma and analyze influence factors. Methods The preoperative CBBCT images 82 female (85 lesions) confirmed by pathology from November, 2011 to December, 2017 Tianjin Medical University Cancer Hospital were included this retrospective study. All underwent immunohistochemical test after operation. Tumor size estimation performed images. Referring measurement pathology, all...

Objective To evaluate the d breast tissue coverage of cone-beam computed tomography (CBBCT) compared with conventional digital mammography. Methods CBBCT scans and mammography in 96 patients (141 breasts) over age 35 were prospectively assessed study. CBBCT performed within 1 week after mammography. Superior, inferior, medial, lateral, posterior evaluated, respectively. It wasconsidered as positive if there was a coverage. McNemar test used to assess differences between...

Aggressive fibromatosis (AF), also known as desmoid tumor or desmoid-type fibromatosis, is a rare soft tissue neoplasm that can occur in almost any part of the body. Although it benign disease, AF aggressive and infiltrative has high recurrence rate after surgery. Common sites for intra-abdominal are small bowel mesentery, retroperitoneum, pelvis. colon extremely rare.

The high rate of new HIV infections, particularly in Sub-Saharan Africa, emphasizes the need for a safe and effective vaccine to prevent acquired immunodeficiency syndrome (AIDS). To date, only trial that has exhibited protective efficacy humans was RV144 study completed Thailand. finding protection correlated with antibodies gp120 suggested increasing quality or magnitude antibody response recognize might improve modest yet significant (31.2%) achieved this immunization regimen. However,...

Although, progesterone has been used for many years in women with threatened abortion; no controlled epidemiological studies of perinatal outcomes pregnant treatment have published yet. However, several case reports show a close relationship between and the development infantile hemangioma. A surprising high percentage (approximately 70%) mothers infants hemangioma proved to take early pregnancy (usually second third month pregnancy). So use may be potential cause This dysregulation...