Honglei Shi

ORCID: 0000-0002-0406-519X
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About
Contact & Profiles
Research Areas
  • Asthma and respiratory diseases
  • Kidney Stones and Urolithiasis Treatments
  • IL-33, ST2, and ILC Pathways
  • Eosinophilic Esophagitis
  • Inhalation and Respiratory Drug Delivery
  • COVID-19 Clinical Research Studies
  • Urinary Bladder and Prostate Research
  • Respiratory viral infections research
  • Pediatric health and respiratory diseases
  • Respiratory and Cough-Related Research
  • Nanoplatforms for cancer theranostics
  • Pediatric Urology and Nephrology Studies
  • Pneumonia and Respiratory Infections
  • Ferroptosis and cancer prognosis
  • Advancements in Transdermal Drug Delivery
  • Fiber-reinforced polymer composites
  • Photodynamic Therapy Research Studies
  • Nanoparticle-Based Drug Delivery
  • Cardiovascular Disease and Adiposity
  • Advanced biosensing and bioanalysis techniques
  • Antimicrobial Peptides and Activities
  • Catalysis and Hydrodesulfurization Studies
  • Microbial infections and disease research
  • Infectious Encephalopathies and Encephalitis
  • Interstitial Lung Diseases and Idiopathic Pulmonary Fibrosis

Capital Medical University
2024-2025

Beijing Chao-Yang Hospital
2024-2025

Xuzhou Medical College
2020-2025

Jiangsu University
2013-2025

Fifth Affiliated Hospital of Sun Yat-sen University
2020-2025

Sun Yat-sen University
2020-2025

Nanjing Medical University
2023-2024

Sun Yat-sen Memorial Hospital
2023-2024

Changzhou No.2 People's Hospital
2023

Chinese Academy of Geological Sciences
2022

Cancer of the bladder is one most common and life-threatening. Compared with traditional delivery methods, intravesical administration reduces amount drugs required, increases reaching lesion site, minimizes systemic exposure to therapeutic agents. To overcome limitations urinary voiding, low urothelium permeability, intermittent catheterization for large dilution irrigation in bladder, magnetic photothermal-responsive folate receptor-targeted thermal liposomes (FA-TMLs) were designed...

10.2147/ijn.s329621 article EN cc-by-nc International Journal of Nanomedicine 2021-11-01

Abdominal obesity, especially visceral fat, may have negative effects on the development and progression of prostate cancer (PCa). A body shape index (ABSI) can more accurately measure fat accumulation. This study aimed to investigate association between ABSI PCa in US adults.

10.1007/s11255-023-03917-2 article EN cc-by International Urology and Nephrology 2024-01-12

Asthma is a common chronic inflammatory disease of the airways, which exhibits significant heterogeneity in clinical symptoms, severity, and treatment outcomes, thus posing serious threat to public health.[1] Results from China Pulmonary Health (CPH) study indicate that prevalence asthma among Chinese individuals aged ≥20 years 4.2%.[2] The Global Initiative for (GINA) emphasizes goal achieve "overall control asthma", meaning both achieving current symptom reducing risk future attacks.[3]...

10.1097/cm9.0000000000003507 article EN cc-by-nc-nd Chinese Medical Journal 2025-03-14

Type 2 innate lymphoid cells (ILC2s) are essential for maintaining immune regulation and promoting tissue homeostasis in allergic asthma. How the development of gut microbiota on neonatal ILC2s influences airway inflammation remains unclear. Here we focus offspring ILC2 context alterations maternal microbiota. C57BL/6 mice were gavaged with OM-85 during pregnancy and/or lactation, ILC2-driven OVA-sensitized adult was observed. early life investigated using recombinant (r)IL-33, rIL-25...

10.1111/pai.70044 article EN Pediatric Allergy and Immunology 2025-02-01

To investigate and analyze the risk factors of urological infection after laparoscopic ureterolithotomy. In this retrospective study, 312 patients who underwent ureterolithotomy were included. Among them, 164 developed post-surgery. Key for identified using univariate multivariate regression analyses. A clinical nomogram was constructed based on these factors, its predictive accuracy assessed concordance index (C-index) calibration plot. Univariate analyses age >75 years old (95% CI...

10.62347/hnmg5196 article EN American Journal of Translational Research 2025-01-01

To investigate the effectiveness of impulse oscillometry (IOS) and its combination with fractional expiratory nitric oxide (FeNO) in distinguishing inadequately controlled asthma (ICA) from well-controlled (WCA) adults. Adult patients aged 18 above were recruited underwent routine blood tests, FeNO, IOS, spirometry before after bronchodilator administration on same day. Asthma control level was assessed using Control Test (ACT) scores; WCA defined as a score 20, while ICA 20 or below....

10.2147/jaa.s516257 article EN cc-by-nc Journal of Asthma and Allergy 2025-04-01

Abstract Background VHL mutation is the most common in clear cell renal carcinoma (ccRCC). Here, we developed and validated an immune-related signature to predict prognosis of ccRCC with mutations. Methods status RNA expression were analysed TCGA datasets our cohort. LASSO Cox analysis was performed develop signature. Candidate genes for differentially expressed between VHLwt VHLmut patients. Results mutations resulted downregulation immune response ccRCC. To signature, constructed by that...

10.1186/s12935-020-01670-5 article EN cc-by Cancer Cell International 2020-12-01

Deaths attributed to Coronavirus Disease 2019 (COVID-19) are mainly due severe hypoxemic respiratory failure. Although the inflammatory storm has been considered main pathogenesis of COVID-19, hypersensitivity may be another important mechanism involved in cases, which have a perfect response corticosteroids (CS).We detected serum level anti-SARS-CoV-2-spike S1 protein-specific IgE (SP-IgE) and anti-SARS-CoV-2 nucleocapsid (NP-IgE) COVID-19. Correlation levels specific clinical severity were...

10.1111/cea.14023 article EN Clinical & Experimental Allergy 2021-09-27

Abstract Background Epidemiological observational studies have elucidated a correlation between rheumatoid arthritis (RA) and bronchiectasis. However, the causal nature of this association remains ambiguous. To clarify potential linkage, we conducted two-sample Mendelian randomization (MR) analysis to explore bidirectional causality RA Methods Summary statistics for bronchiectasis were obtained from IEU OpenGWAS database We employed various methods, including inverse variance weighting...

10.1186/s13075-024-03336-3 article EN cc-by Arthritis Research & Therapy 2024-05-23
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