- Infection Control in Healthcare
- Cervical Cancer and HPV Research
- Global Maternal and Child Health
- Vaccine Coverage and Hesitancy
- Mobile Health and mHealth Applications
- Global Cancer Incidence and Screening
- COVID-19 Clinical Research Studies
- Geriatric Care and Nursing Homes
- COVID-19 and healthcare impacts
- Acute Myeloid Leukemia Research
- Health Policy Implementation Science
- CAR-T cell therapy research
- Healthcare professionals’ stress and burnout
- Primary Care and Health Outcomes
- SARS-CoV-2 and COVID-19 Research
- Migration, Health and Trauma
- T-cell and Retrovirus Studies
- Mental Health Treatment and Access
- HIV/AIDS Impact and Responses
- Ubiquitin and proteasome pathways
- Maternal and fetal healthcare
- Nosocomial Infections in ICU
- Antibiotic Use and Resistance
- Hematopoietic Stem Cell Transplantation
- COVID-19 and Mental Health
Universitätsmedizin Göttingen
2021-2025
University Hospital of Geneva
2011-2025
Charité - Universitätsmedizin Berlin
2015-2024
University Medical Center
2024
University of Helsinki
2024
University Hospital Leipzig
2024
University of Geneva
2024
Katholische Stiftungshochschule München
2020-2024
University Hospital Cologne
2024
Robert Koch Institute
2018-2022
Residents in long-term care facilities (LTCF) are a vulnerable population group. Coronavirus disease (COVID-19)-related deaths LTCF residents represent 30-60% of all COVID-19 many European countries. This situation demands that countries implement local and national testing, infection prevention control, monitoring programmes for order to identify clusters early, decrease the spread within between reduce size severity outbreaks.
Background The aim of this study is to explore factors influencing the engagement health and social professions students during COVID-19 pandemic. While antecedents have been studied previously, under pandemic conditions not yet investigated. Furthermore, there a particular need for research among in programs, as these are particularly affected by As theoretical basis, draws on demands-resources-theory. It hypothesized that pandemic-related personal resources drive pandemic, demands...
Objective This article describes the characteristics and early implementation experiences of community behavioral health agencies that received Primary Behavioral Health Care Integration (PBHCI) grants from Substance Abuse Mental Services Administration to integrate primary care into programs for adults with serious mental illness. Methods Data were collected 56 programs, across 26 states, PBHCI in 2009 (N=13) or 2010 (N=43). The authors systematically extracted quantitative qualitative...
The burden of health-care associated infections in low-income countries is high. Adequate hand hygiene considered the most effective measure to reduce transmission nosocomial pathogens. We aimed assess compliance with and perception knowledge about before after implementation a multimodal campaign designed by World Health Organization.The study was carried out at Asella Teaching Hospital, university hospital referral centre for population 3.5 million Arsi Zone, Central Ethiopia. Compliance...
Antenatal care (ANC) has the potential to identify and manage obstetric complications, educate women about risks during pregnancy promote skilled birth attendance childbirth. The aim of this study was assess women’s knowledge danger signs factors associated with in Ambanja, Madagascar. It also sought evaluate whether participation a mobile health (mHealth) project that aimed provide comprehensive ANC pregnant remote areas influenced signs. From April October 2015, non-random, convenience...
The aim of this study was to explore the perspectives healthcare providers on advantages and disadvantages integrating HIV care services, including highly active antiretroviral therapy (HAART), into antenatal (ANC) clinics in rural Kenya. We conducted a qualitative using in-depth interviews thematic analysis; 36 from six health centres Nyanza Province, Kenya participated. Effects service included increased workload due incorporation specialised services ANC clinics. Providers observed that...
Background Madagascar's maternal health mortality ratio in 2013 was 478 deaths per 100,000 live births. Most are related to direct complications during pregnancy and childbirth could be reduced by providing comprehensive antenatal care (ANC). Objective The objective of the study assess usability feasibility a mobile system (mHealth) provide high-quality ANC, according World Health Organization (WHO) recommendations. Methods PANDA (Pregnancy And Newborn Diagnostic Assessment) is an...
Background Despite many efforts, maternal mortality remains a major burden in most developing countries. Mobile health (mHealth) has the potential to improve access obstetric care through apps that help patients and providers. Objective This study aimed use mHealth provide antenatal (ANC) 1446 pregnant women rural area Madagascar evaluate quality of ANC provided by an system designed change behaviors providers patients. Methods We included who attended visits from 2015 2019 using called...
Abstract Background Cervical cancer is the second leading cause of cancer-related death among women in sub-Saharan countries, constituting a major public health concern. In Cameroon, cervical ranks as most common type and deaths, mainly due to lack prevention. Objectives Our first main objective was understand barriers affecting women’s decision-making process regarding participation screening program Dschang district (West Cameroon). Second, we aimed explore acceptability perception...
The COVID-19 pandemic has been a challenging period of upheaval for higher education students. This study aims to assess the factors associated with psychological stress during among sample students in health-related fields at Munich universities Germany. Students (n = 623) from KSH and LMU completed an online cross-sectional survey. Information on demographics academic everyday difficulties due as well data physical mental health were collected. Multivariable logistic regression analyses...
Background: Two-dose COVID-19 vaccination often results in poor humoral response rates patients with hematologic malignancies (HMs); yet responses to booster vaccines and the risk of infection post-booster are mostly uncertain. Methods: We included 200 outpatients HMs predominantly lymphoid neoplasms (96%, 191/200) our academic center reported on responses, which were assessed by measurement anti-spike IgG antibodies peripheral blood as early 14 days after mRNA-based prime-boost vaccination,...
ABSTRACT Provirus Integration site for Moloney leukemia virus (Pim) family members are well‐known oncogenes, with an expression that is restricted to few cell types including hematopoietic cells in adult organisms, making it a promising target lymphoma treatment. Indeed, previous studies mature T‐cell (mTCL) revealed frequent upregulation of Pim expression. Nevertheless, inhibition kinases showed only minor effects on the viability mTCL so far. Thus, we here addressed cellular responses...
In 2020, approximately 281 million people lived in a country other than their of birth. Geneva, Switzerland, born countries constitute 40.2% the population. We aimed to describe population pregnant women delivering at University Hospitals Geneva (HUG) maternity department and identify associations between legal status, migration economic precarity with quality care health outcomes. performed an exploratory cross-sectional retrospective study including all who delivered HUG’s May 2019...
Abstract Background Cervical cancer is the fourth most frequent among women, with 90% of cervical cancer-related deaths occurring in low- and middle-income countries like Cameroon. Visual inspection acetic acid often used low-resource settings to screen for cancer; however, its accuracy can be limited. To address this issue, Swiss Federal Institute Technology Lausanne University Hospitals Geneva are collaborating develop an automated smartphone-based image classifier that serves as a...
College retention rates continue to be a national issue in the United States. Solutions decrease attrition have not been adequately tested nursing student population.The purpose of this study was investigate benefits peer-mentoring program baccalaureate from perspectives both mentor and mentee.Electronic surveys were used evaluate impact program.Responses showed beneficial academically, personally, professionally. A large majority (89%-96%) mentees agreed or strongly with positive effects...
Human papillomavirus (HPV) self-sampling (Self-HPV) is a promising strategy to improve cervical cancer screening coverage in low-income countries. However, issues associated with women who prefer conventional HPV clinical-sampling over may affect participation. To address this issue, our study assessed factors women's preferences related Self-HPV. This was embedded large clinical trial recruiting aged 30-49 years primary HPV-based termed "3T-Approach" (for Test-Triage-Treatment), launched...
Objective Cervical cancer in Cameroon ranks as the second most frequent among women and leading cause of cancer-related deaths, mainly due to lack prevention. Our principal objective was explore potential barriers an human papillomavirus (HPV)-based cervical screening from a healthcare provider (HCP) perspective low-income context. Second, we aimed acceptability single-visit approach using HPV self-sampling. Settings The study took place District hospital Dschang, Cameroon. Participants...
We sought to determine the rate of Staphylococcus aureus rectovaginal colonization and positive newborn blood cultures. Routinely obtained group B streptococcus (GBS) specimens were cultured for S. using standard microbiology procedures. aureus– GBS-positive cultures in infants less than 3 days old determined from our database. Overall, 1488 obtained. Rates GBS, aureus, methicillin-resistant (MRSA) 20.2%, 8.2%, 1.7%, respectively. Cultures methicillin-susceptible (MSSA) GBS or MRSA 1.6% 0.3%...
Background Computer-aided detection and diagnosis (CAD) systems can enhance the objectivity of visual inspection with acetic acid (VIA), which is widely used in low- middle-income countries (LMICs) for cervical cancer detection. VIA’s reliance on subjective health care provider (HCP) interpretation introduces variability diagnostic accuracy. CAD tools address some limitations; nonetheless, understanding contextual factors affecting integration essential effective adoption sustained use,...
Abstract The superior olivary complex (SOC) is an auditory brainstem region that represents a favourable system to study rapid neurotransmission and the maturation of neuronal circuits. Here we performed serial analysis gene expression (SAGE) on SOC in 60‐day‐old Sprague–Dawley rats identify genes specifically important for its function create transcriptome reference subsequent identification age‐related or disease‐related changes. Sequencing 31 035 tags identified 10 473 different...
Second allogeneic stem cell transplantation (allo-SCT2) represents a rescue option for selected patients (pts) with relapsed/refractory (r/r) acute myeloid leukemia (AML). Still, relapse rates post-allo-SCT2 remain high and effective anti-relapse strategies predictive biomarkers to be defined. We here analyzed cohort of 41 AML undergoing allo-SCT2 in our center. Allo-SCT2 induced third hematologic complete remission (CR) 37 pts, at costs 36% non-relapse mortality rate. Furthermore, 19 pts...
The essential role of infection prevention in long-term care facilities has become evident during the current SARS-CoV‑2 pandemic. In order to obtain a reliable database on nosocomial infections and antibiotic use, European Centre for Disease Prevention Control (ECDC) initiated third point prevalence survey from 2016 2017 (HALT-3).In Germany, 131 with 10,565 residents participated voluntarily. On single day 2016, number and/or uses antibiotics as well characteristics risk factors were...
The estimated burden of maternal morbidities in lower-income countries, such as Madagascar, is high. However, there still a lack data on morbidities, part due to an absence standardized assessment tools. This cross-sectional study aims report among 1015 women the district Ambanja, and describe advantages limitations mHealth system.Data were collected using PANDA (pregnancy newborn diagnosis assessment) system, device that incorporates WHO recommendations for antenatal care (ANC). Data,...