A5019242163- Cardiovascular Syncope and Autonomic Disorders
- Congenital Heart Disease Studies
- Heart Rate Variability and Autonomic Control
- Cardiac Arrhythmias and Treatments
- Ophthalmology and Eye Disorders
- Coronary Artery Anomalies
- Botulinum Toxin and Related Neurological Disorders
- Congenital heart defects research
- Vascular anomalies and interventions
- Cardiac Structural Anomalies and Repair
- Heart Failure Treatment and Management
- Tracheal and airway disorders
- Neurology and Historical Studies
- Electronic Health Records Systems
- Obstructive Sleep Apnea Research
- Sympathectomy and Hyperhidrosis Treatments
- Biomedical Text Mining and Ontologies
- Cardiac Valve Diseases and Treatments
- Clinical practice guidelines implementation
- Cardiovascular Function and Risk Factors
- Genetic Neurodegenerative Diseases
- Glycogen Storage Diseases and Myoclonus
- Phonocardiography and Auscultation Techniques
- Traumatic Brain Injury Research
- Calcium signaling and nucleotide metabolism
Philadelphia University
2019-2020
Children's Hospital of Philadelphia
2010-2018
University of Pennsylvania
2015-2018
Jeffrey Modell Foundation
2011-2017
Keesler Medical Center
2003
University of Colorado Health
1998
Boston Children's Hospital
1998
Postural orthostatic tachycardia syndrome (POTS) is a chronic and often disabling disorder characterized by intolerance with excessive heart rate increase without hypotension during upright posture. Patients experience constellation of other typical symptoms including fatigue, exercise gastrointestinal distress. A patient POTS female child-bearing age, who first displays in adolescence. The onset may be precipitated immunological stressors such as viral infection. variety pathophysiologies...
Abstract An internationally approved and globally used classification scheme for the diagnosis of CHD has long been sought. The International Paediatric Congenital Cardiac Code (IPCCC), which was produced maintained by Society Nomenclature Heart Disease (the Society), is widely, but spawned many “short list” versions that differ in content depending on user. Thus, efforts to have a uniform identification patients with using single up-to-date coordinated nomenclature system continue be...
Abstract Substantial progress has been made in the standardization of nomenclature for paediatric and congenital cardiac care. In 1936, Maude Abbott published her Atlas Congenital Cardiac Disease, which was first formal attempt to classify heart disease. The International Paediatric Code ( IPCCC ) is now utilized worldwide most recently become component Eleventh Revision Classification Diseases ICD-11 ). recent publication 2017. This manuscript provides an updated 2021 version . Society...
Limited data exist on long-term outcomes in individuals with postural orthostatic tachycardia syndrome (POTS). We designed an electronic questionnaire assessing various aspects of among patients diagnosed and treated a single-center pediatric POTS clinical program.
Abstract Objective The aim of this study was to identify and evaluate demographic clinical features paediatric patients with postural orthostatic tachycardia syndrome in a tertiary hospital speciality clinic. Method This is retrospective review data obtained during initial outpatient evaluation. Results A total 708 met the evaluation criteria. Female outnumbered males, 3.45:1. Caucasians were over-represented at 94.1% patients. Median age diagnosis 15.7 years. Joint hypermobility occurred...
The National Institutes of Health hosted a workshop in 2019 to build consensus around the current state understanding pathophysiology postural orthostatic tachycardia syndrome (POTS) and identify knowledge gaps that must be addressed enhance clinical care POTS patients through research. This second (of two) articles summarizes gaps, outlines research priorities for POTS.POTS is complex, multi-system, chronic disorder autonomic nervous system characterized by intolerance without hypotension....
Substantial progress has been made in the standardization of nomenclature for paediatric and congenital cardiac care. In 1936, Maude Abbott published her Atlas Congenital Cardiac Disease, which was first formal attempt to classify heart disease. The International Paediatric Code (IPCCC) is now utilized worldwide most recently become component Eleventh Revision Classification Diseases (ICD-11). recent publication IPCCC 2017. This manuscript provides an updated 2021 version IPCCC.The Society...
Abstract Background Postural orthostatic tachycardia syndrome (POTS) is a complex disorder with serious health consequences, while its etiology remains largely elusive. Objective The purpose of this study was to investigate the genetic landscape POTS using genomic approaches in unique pediatric cohort. Methods We conducted combined genome wide genotyping and whole exome sequencing (WES) systemically examine molecular mechanisms pathogenesis. patients were genotyped as two independent...
Postural orthostatic tachycardia syndrome (POTS) is the most common of several types dysautonomia, characterized by dysfunction autonomic nervous system manifesting with symptoms intolerance or without associated hypotension and excessive excitation. Given numerous presenting musculoskeletal POTS its known associations other clinical entities like Ehlers-Danlos syndrome, constitutes an unusual treatment challenge which orthopaedic surgeon related healthcare providers should be aware.We...
Purpose: Postural orthostatic tachycardia syndrome (POTS), an increasingly recognized dysautonomia, may affect as many 3,000,000 Americans. Concurrently, prevalence estimates suggest 10% of individuals identify lesbian, gay, bisexual, transgender, or questioning/queer. The preponderance female POTS patients implies hormonal differences between natal sexes and their role in POTS. Transgender using hormone therapies offer further insight into the mechanism There have been no previously...