- Cardiac pacing and defibrillation studies
- Cardiac electrophysiology and arrhythmias
- Cardiac Arrhythmias and Treatments
- Mobile Health and mHealth Applications
- Heart Failure Treatment and Management
- Atrial Fibrillation Management and Outcomes
- Technology Use by Older Adults
- Cardiovascular Function and Risk Factors
- Health Systems, Economic Evaluations, Quality of Life
- Electronic Health Records Systems
- Medication Adherence and Compliance
- Digital Mental Health Interventions
- Congenital Heart Disease Studies
- Clinical practice guidelines implementation
- Ion channel regulation and function
- ECG Monitoring and Analysis
- Cardiac Valve Diseases and Treatments
- Persona Design and Applications
- Primary Care and Health Outcomes
- Cardiac Arrest and Resuscitation
- Healthcare Policy and Management
- Chronic Disease Management Strategies
- Heart Rate Variability and Autonomic Control
- Cardiovascular Syncope and Autonomic Disorders
- Wireless Body Area Networks
Parkview Health
2015-2024
Indiana University School of Medicine
1978-2024
Indiana University Fort Wayne
2016-2024
Indiana University
2019-2024
University School
2024
Indiana University – Purdue University Indianapolis
1978-2023
California State University, San Marcos
2023
Parkview Mirro Center for Research and Innovation
2013-2021
Indiana University Indianapolis
2020
Indianapolis Zoo
2020
The aim of this study was to describe usage the wearable cardioverter-defibrillator (WCD) during mandated waiting periods following myocardial infarction (MI) for patients perceived be at high risk sudden cardiac arrest (SCA). Current device guidelines and insurance coverage require either 40 days or 3 months before implanting a post-myocardial (MI), depending on whether not acute revascularization undertaken. We assessed characteristics outcomes who had WCD prescribed in first post-MI....
Background User-centered design (UCD) is a powerful framework for creating useful, easy-to-use, and satisfying mobile health (mHealth) apps. However, the literature seldom reports practical challenges of implementing UCD, particularly in field mHealth. Objective This study aims to characterize encountered propose strategies when UCD Methods Our multidisciplinary team implemented process evaluate app older adults with heart failure. During after this process, we documented they used or...
We studied the interaction of disopyramide, quinidine, and procainamide with cardiac muscarinic receptors. In electrophysiological experiments, effects procainamide, atropine were determined on spontaneously depolarizing guinea pig right atria (GPRA) both in presence absence pharmacologically induced (physostigmine) cholinergic stimulation. All four agents demonstrated a concentration-dependent antagonism negative chronotropic physostigmine. The order anticholinergic potency was greater than...
Abstract Objectives To determine the impact of tethered personal health record (PHR) use on patient engagement and intermediate outcomes among patients with coronary artery disease (CAD). Methods Adult CAD ( N = 200) were enrolled in this prospective, quasi-experimental observational study. Each received a PHR account training its use. PHRs populated information from electronic medical records, hosted by Health Information Exchange. Intermediate including blood pressure, body mass index,...
Objective:Telemental health (TMH) resources are plentiful; however, we know little about college students' opinions such resources. We aimed to examine previous use of and willingness several types TMH resources.Participants:Students (N = 662) from two U.S. Midwestern colleges participated.Methods:Using an online survey in spring 2017, measured depression, anxiety, stress, suicidal thoughts, preferences for care options during distress, interest anonymous chats with trained nonprofessionals,...
Abstract Patients with heart failure (HF) are commonly implanted cardiac resynchronization therapy (CRT) devices as part of their treatment. Presently, they cannot directly access the remote monitoring (RM) data generated from these devices, representing a missed opportunity for increased knowledge and engagement in care. However, electronic health sharing can create information overload issues both clinicians patients, some older patients may not be comfortable using technology (i.e.,...
We studied the electrophysiological effects of optical isomers disopyramide and quinidine on canine cardiac Purkinje fibers. Conventional microelectrode techniques were employed to study racemic disopyramide, (+)-disopyramide, (-)-disopyramide, quinidine, quinine. Racemic prolonged action potential duration (APD) measured at 90% repolarization. In contrast, (-)-disopyramide quinine shortened APD. These directionally opposite repolarization observed throughout 60 minutes exposure drug...
We studied the role of anticholinergic properties disopyramide and quinidine in mediating electrophysiological effects these agents on isolated cardiac tissue.In right atria, disopyramide, quinidine, procainamide administered alone elicited negative chronotropic responses.However, after cholinergic stimulation with physostigmine (1 X 10" 6 M), produced a positive response.Procainamide, when under same conditions increased stimulation, responses similar to those observed it was given alone.In...
High rates of mental illness, stress, and suicidality among teens constitute a major public health concern in the United States. However, treatment remain low, partially because barriers that could be mitigated with tech-based telemental (TMH) resources, separate from or addition to traditional care.This study aimed analyze TMH resource usage by high school students establish current user characteristics provide framework for future development.A total 2789 were surveyed regarding...
Abstract Objective Researchers conduct studies with selection biases, which may limit generalizability and outcomes of intervention research. In this methodological reflection, we examined demographic health characteristics implantable cardioverter defibrillator patients who were excluded from an informatics due to lack access a computer and/or the internet. Materials Methods Using information gathered surveys electronic records, compared group on factors, skills, patient activation, medical...
Background Patients at risk for sudden cardiac death or having suffered arrest may receive an implantable cardioverter defibrillator (ICD). This device provides monitoring and therapy life-threatening heart rhythms. Remote of ICDs has decreased the time between abnormal rhythm events clinic follow-up. Currently, data transmitted from are reviewed stored by clinic, but patients do not have access to data. While connecting directly with their ICD potential enhance engagement in care improve...
Patients with atrial fibrillation (AF) demonstrate persistent knowledge gaps regarding their condition and a substandard adherence to oral anticoagulant (OAC) medication, which contribute thromboembolic stroke other clot-related complications. Tailored patient education medication reminders may help reduce these negative health outcomes. We sought improve disease among sample of AF patients using tailored nudges. The intervention leveraged three digital technologies: portal, an...
Abstract Objective Our primary objectives were to examine adherence rates across two technologies (e-prescribing software and smart pill bottle) with cross-validation from alert-triggered messaging within the patient electronic health record (EHR) portal explore benefits challenges faced by atrial fibrillation (AF) patients in using a bottle. Materials Methods We triangulated rate of oral anticoagulant medication among 160 AF over 6 months an EHR combination data AdhereTech© Wireless Smart...