- Immune Cell Function and Interaction
- Child Nutrition and Feeding Issues
- Autism Spectrum Disorder Research
- CAR-T cell therapy research
- Amoebic Infections and Treatments
- RNA Interference and Gene Delivery
- Extracellular vesicles in disease
- Systemic Lupus Erythematosus Research
- Pancreatitis Pathology and Treatment
- Circular RNAs in diseases
- Curcumin's Biomedical Applications
- Lymphoma Diagnosis and Treatment
- Infant Development and Preterm Care
- Dermatological and COVID-19 studies
Shanghai Children's Medical Center
2018-2024
Harbin Medical University
2023
First Affiliated Hospital of Harbin Medical University
2023
First People's Hospital of Yunnan Province
2023
Cangzhou Central Hospital
2023
Excessive proliferation and activation of B cells, resulting in the production various autoantibodies, is a crucial link significant feature pathogenesis systemic lupus erythematosus (SLE), as well pathological basis multiorgan damage. However, whether exosomes derived from human umbilical cord mesenchymal stem cells (hucMSCs-Exo) are involved immune regulation SLE has not been clarified. Therefore, our study aimed to investigate efficacy hucMSCs-Exo for treating SLE. peripheral blood...
Background T cell lymphomas (TCL) are a group of heterogeneous diseases with over 40 subtypes. In this study, we identified novel TCL subtype which was featured by unique receptor (TCR) presentation, α, β and γ chains were co-existing in single malignant cell. Case presentation A 45-year-old male patient diagnosed lymphoma after 2-month abdominal distension liver enlargement. Combining histology review, PET-CT scanning immunophenotyes, the not classified to any existing To better understand...
Objective: To explore the clinical characteristics of various types infected pancreatic necrosis(IPN) and prognosis different treatment methods in imaging classification IPN proposed. Methods: The data 126 patients with admitted to Department Pancreatic Biliary Surgery, First Affiliated Hospital Harbin Medical University from December 2018 2021 were analyzed retrospectively. There 70 males(55.6%) 56 females(44.4%), age(M(IQR)) 44(17)years (range: 12 87 years). 67 cases(53.2%) severe acute...
This study investigated the role of curcumin nanocarriers carrying TAR-RNA binding protein (TRBP) in hepatocellular carcinoma (HCC). We conducted a retrospective analysis 60 HCC tissue samples and 30 normal liver tissues. TRBP level was measured HCC. Disease-free survival (DFS) overall (OS) were calculated to analyze correlation between expression diagnostic sensitivity Survival factors analyzed using cyclo-oxygen-ase (COX) univariate multivariate analysis. The nanocarriers-loaded siRNA...
Children and adolescent sleep problems are major concerns for parents, health professionals, children youths themselves. For assessing problems, both parent child-report important, with each having its unique features. However, little is known about the correlates of agreement between child self-report. This study evaluated Youth Self-Report Sleep Questionnaire (YSRSQ) parent-reported Children’s Habits (CSHQ) assessed associated sociodemographic factors, as well underlying discrepancies. The...
Studies have shown that maternal emotion and mood during after pregnancy is associated with young children’s sleep disturbances. However, few studies examined this relationship for different trimesters of pregnancy, assessments been limited to infancy. Furthermore, examining both positive negative emotions are lacking. Importantly, potential mediators unclear. We aimed tackle these gaps in a longitudinal cohort study kindergarten children. Participants included 833 kindergarteners mean age...