- Electrochemical Analysis and Applications
- Advanced biosensing and bioanalysis techniques
- Trace Elements in Health
- Electrochemical sensors and biosensors
- DNA and Nucleic Acid Chemistry
- Heavy Metal Exposure and Toxicity
- Analytical Chemistry and Sensors
- Analytical chemistry methods development
- Biosensors and Analytical Detection
- Laser-induced spectroscopy and plasma
- Iron Metabolism and Disorders
- Quantum Dots Synthesis And Properties
- Advanced Chemical Sensor Technologies
- Heavy Metals in Plants
- Nanoparticles: synthesis and applications
- Plant Micronutrient Interactions and Effects
- Selenium in Biological Systems
- Metal complexes synthesis and properties
- Sulfur Compounds in Biology
- Environmental Toxicology and Ecotoxicology
- Molecular Biology Techniques and Applications
- Microfluidic and Capillary Electrophoresis Applications
- Heavy metals in environment
- Phytochemicals and Antioxidant Activities
- Nanoparticle-Based Drug Delivery
Mendel University in Brno
2012-2025
Central European Institute of Technology
2011-2025
Brno University of Technology
2007-2025
Research Institute of Inorganic Chemistry
2022-2025
Charles University
2005-2025
University Hospital in Motol
2023-2025
Indonesia International Institute for Life Sciences
2023
General University Hospital in Prague
2022
Masaryk University
2008-2021
Wroclaw Medical University
2016-2021
Free radicals are chemical particles containing one or more unpaired electrons, which may be part of the molecule. They cause molecule to become highly reactive. The free also known play a dual role in biological systems, as they can either beneficial harmful for living systems. It is clear that there numerous mechanisms participating on protection cell against radicals. In this review, our attention paid metallothioneins (MTs) small, cysteine-rich and heavy metal-binding proteins,...
Carbon nanotubes (CNTs) have been under scientific investigation for more than fifteen years because of their unique properties that predestine them many potential applications. The field nanotechnology and nanoscience push forward to produce CNTs with suitable parameters future It is evident new approaches synthesis need be developed optimized. In this paper we review history, types, structure especially the different methods preparation including arc discharge, laser ablation chemical...
Oxidative stress causes profound alterations of various biological structures, including cellular membranes, lipids, proteins and nucleic acids, it is involved in numerous malignancies. Reduced glutathione (GSH) considered to be one the most important scavengers reactive oxygen species (ROS), its ratio with oxidised (GSSG) may used as a marker oxidative stress. The main aim this study was determine GSH:GSSG blood serum paediatric cancer patients use potential whole procedure optimised...
Deoxynivalenol (DON) is one of several mycotoxins produced by certain Fusarium species that frequently infect corn, wheat, oats, barley, rice, and other grains in the field or during storage. The exposure risk to human directly through foods plant origin (cereal grains) indirectly animal (kidney, liver, milk, eggs). It has been detected buckwheat, popcorn, sorgum, triticale, food products including flour, bread, breakfast cereals, noodles, infant foods, pancakes, malt beer. DON affects...
Chemical investigation of many bacterial and fungal, as well plant species has revealed the presence interesting compounds derived from naphthalene – 1,4-naphthoquinones rarely also 1,2-naphthoquinones. They were detected in families Bignoniaceae, Droseraceae, Plumbaginace, Boraginaceae, Juglandaceae small families, such Dioncophyllaceae or Acanthaceae. Naphthoquinones have very spectrum biological actions, including antibiotic, antiviral, anti-inflammatory, antipyretic, antiproliferative...
Vitamin C (ascorbic acid, ascorbate, AA) is a water soluble organic compound that participates in many biological processes. The main aim of this paper was to utilize two electrochemical detectors (amperometric – Coulouchem III and coulometric CoulArray) coupled with flow injection analysis for the detection ascorbic acid. Primarily, we optimized experimental conditions. conditions were as follows: detector potential 100 mV, temperature 25 °C, mobile phase 0.09% TFA:ACN, 3:97 (v/v) rate 0.13...
The aim of this study was to describe behaviour, kinetics, time courses and limitations the six different fully automated spectrometric methods - DPPH, TEAC, FRAP, DMPD, Free Radicals Blue CrO5. Absorption curves were measured absorbance maxima found. All calibrated using standard compounds Trolox® and/or gallic acid. Calibration determined (relative deviation within range from 1.5 2.5 %). obtained characteristics compared discussed. Moreover, data applied optimize automate all mentioned...
Electrochemical methods provide high potential for investigation of antioxidant compounds, assessment capacity, and measurement electrochemical index. Different types electrodes can be used the assay purposes. The devices stationary or flow through, based on cyclic differential pulse voltammetry as well potentiostatic analysis. are known their suitability food control monitoring levels capacity in other biological samples matrices. In this review, application both analysis plant clinical...