René Kizek

ORCID: 0000-0002-0467-6169
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About
Contact & Profiles
Research Areas
  • Electrochemical Analysis and Applications
  • Advanced biosensing and bioanalysis techniques
  • Trace Elements in Health
  • Electrochemical sensors and biosensors
  • DNA and Nucleic Acid Chemistry
  • Heavy Metal Exposure and Toxicity
  • Analytical Chemistry and Sensors
  • Analytical chemistry methods development
  • Biosensors and Analytical Detection
  • Laser-induced spectroscopy and plasma
  • Iron Metabolism and Disorders
  • Quantum Dots Synthesis And Properties
  • Advanced Chemical Sensor Technologies
  • Heavy Metals in Plants
  • Nanoparticles: synthesis and applications
  • Plant Micronutrient Interactions and Effects
  • Selenium in Biological Systems
  • Metal complexes synthesis and properties
  • Sulfur Compounds in Biology
  • Environmental Toxicology and Ecotoxicology
  • Molecular Biology Techniques and Applications
  • Microfluidic and Capillary Electrophoresis Applications
  • Heavy metals in environment
  • Phytochemicals and Antioxidant Activities
  • Nanoparticle-Based Drug Delivery

Mendel University in Brno
2012-2025

Central European Institute of Technology
2011-2025

Brno University of Technology
2007-2025

Research Institute of Inorganic Chemistry
2022-2025

Charles University
2005-2025

University Hospital in Motol
2023-2025

Indonesia International Institute for Life Sciences
2023

General University Hospital in Prague
2022

Masaryk University
2008-2021

Wroclaw Medical University
2016-2021

Free radicals are chemical particles containing one or more unpaired electrons, which may be part of the molecule. They cause molecule to become highly reactive. The free also known play a dual role in biological systems, as they can either beneficial harmful for living systems. It is clear that there numerous mechanisms participating on protection cell against radicals. In this review, our attention paid metallothioneins (MTs) small, cysteine-rich and heavy metal-binding proteins,...

10.3390/ijms14036044 article EN International Journal of Molecular Sciences 2013-03-15

Carbon nanotubes (CNTs) have been under scientific investigation for more than fifteen years because of their unique properties that predestine them many potential applications. The field nanotechnology and nanoscience push forward to produce CNTs with suitable parameters future It is evident new approaches synthesis need be developed optimized. In this paper we review history, types, structure especially the different methods preparation including arc discharge, laser ablation chemical...

10.1039/c1jm12254a article EN Journal of Materials Chemistry 2011-01-01

Oxidative stress causes profound alterations of various biological structures, including cellular membranes, lipids, proteins and nucleic acids, it is involved in numerous malignancies. Reduced glutathione (GSH) considered to be one the most important scavengers reactive oxygen species (ROS), its ratio with oxidised (GSSG) may used as a marker oxidative stress. The main aim this study was determine GSH:GSSG blood serum paediatric cancer patients use potential whole procedure optimised...

10.3892/ol.2012.931 article EN Oncology Letters 2012-01-01

Deoxynivalenol (DON) is one of several mycotoxins produced by certain Fusarium species that frequently infect corn, wheat, oats, barley, rice, and other grains in the field or during storage. The exposure risk to human directly through foods plant origin (cereal grains) indirectly animal (kidney, liver, milk, eggs). It has been detected buckwheat, popcorn, sorgum, triticale, food products including flour, bread, breakfast cereals, noodles, infant foods, pancakes, malt beer. DON affects...

10.2478/v10102-010-0019-x article EN Interdisciplinary Toxicology 2010-01-01

Chemical investigation of many bacterial and fungal, as well plant species has revealed the presence interesting compounds derived from naphthalene – 1,4-naphthoquinones rarely also 1,2-naphthoquinones. They were detected in families Bignoniaceae, Droseraceae, Plumbaginace, Boraginaceae, Juglandaceae small families, such Dioncophyllaceae or Acanthaceae. Naphthoquinones have very spectrum biological actions, including antibiotic, antiviral, anti-inflammatory, antipyretic, antiproliferative...

10.2174/157341209787314936 article EN Current Pharmaceutical Analysis 2009-01-30

Vitamin C (ascorbic acid, ascorbate, AA) is a water soluble organic compound that participates in many biological processes. The main aim of this paper was to utilize two electrochemical detectors (amperometric – Coulouchem III and coulometric CoulArray) coupled with flow injection analysis for the detection ascorbic acid. Primarily, we optimized experimental conditions. conditions were as follows: detector potential 100 mV, temperature 25 °C, mobile phase 0.09% TFA:ACN, 3:97 (v/v) rate 0.13...

10.3390/s8117097 article EN cc-by Sensors 2008-11-06

The aim of this study was to describe behaviour, kinetics, time courses and limitations the six different fully automated spectrometric methods - DPPH, TEAC, FRAP, DMPD, Free Radicals Blue CrO5. Absorption curves were measured absorbance maxima found. All calibrated using standard compounds Trolox® and/or gallic acid. Calibration determined (relative deviation within range from 1.5 2.5 %). obtained characteristics compared discussed. Moreover, data applied optimize automate all mentioned...

10.3390/molecules15128618 article EN cc-by Molecules 2010-11-29

Electrochemical methods provide high potential for investigation of antioxidant compounds, assessment capacity, and measurement electrochemical index. Different types electrodes can be used the assay purposes. The devices stationary or flow through, based on cyclic differential pulse voltammetry as well potentiostatic analysis. are known their suitability food control monitoring levels capacity in other biological samples matrices. In this review, application both analysis plant clinical...

10.1016/s1452-3981(23)12902-6 article EN cc-by-nc-nd International Journal of Electrochemical Science 2013-06-01
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