- Trace Elements in Health
- Heavy Metal Exposure and Toxicity
- Barrier Structure and Function Studies
- Precipitation Measurement and Analysis
- Advanced Glycation End Products research
- Radio Wave Propagation Studies
- Curcumin's Biomedical Applications
- PI3K/AKT/mTOR signaling in cancer
- Iron Metabolism and Disorders
- Neurological Disease Mechanisms and Treatments
- Satellite Communication Systems
- Cancer Mechanisms and Therapy
- Cancer Cells and Metastasis
- Digital Imaging in Medicine
- Cancer-related gene regulation
- Blood Pressure and Hypertension Studies
- Lipid metabolism and disorders
- Peptidase Inhibition and Analysis
- Helicobacter pylori-related gastroenterology studies
- Hedgehog Signaling Pathway Studies
- Radiomics and Machine Learning in Medical Imaging
- Natural Antidiabetic Agents Studies
- Pharmaceutical Economics and Policy
- Aluminum toxicity and tolerance in plants and animals
- Oral microbiology and periodontitis research
University of Nebraska Medical Center
2021-2024
Silchar Medical College and Hospital
2024
Central Food Technological Research Institute
2016-2023
Nebraska Medical Center
2023
In-Q-Tel
2017
Calcutta Research Group
2004
Abstract Oxidative stress plays a major role in the pathogenesis of diabetes mellitus, which further exacerbates damage cardiac, hepatic and other tissues. We have recently reported that Zn supplementation beneficially modulates hyperglycaemia hypoinsulinaemia, with attendant reduction associated metabolic abnormalities diabetic rats. The present study assessed potential modulating oxidative cardioprotective effects Diabetes was induced Wistar rats streptozotocin, groups were treated 5-...
The cause and effect relationship between diabetes zinc is complex unclear. This animal study has examined the potential of supplementation in beneficial modulating hyperglycemia, insulin secretion, metabolic abnormalities associated with diabetes. was conducted streptozotocin-induced diabetic rats. Groups hyperglycemic rats were subjected to dietary interventions for 6 weeks (5 times 10 normal level). Supplemental-zinc-fed groups showed significant control on hyperglycemia hypoinsulinemia....
Colorectal cancer (CRC) is a leading cause of the cancer-related deaths worldwide. Thus, developing novel and targeted therapies for inhibiting CRC progression metastasis urgent. Several studies, including ours, have reported causal role an upregulated claudin-1 expression in promoting through activation Src β-catenin-signaling. In murine models colon tumorigenesis, overexpression promotes oncogenic properties such as transformation invasiveness. Conversely, downregulation inhibits...
Zinc depletion during diabetes projects a role for zinc nutrition in this condition.
MASTL is upregulated in colorectal cancer; however, its role colitis and colitis-associated cancer poorly understood. This study the first to draw a link between IL-22, proinflammatory/intestinal epithelial recovery-promoting cytokine that also implicated colon tumorigenesis. We propose IL-22 increases protein stability by promoting association with CAIX potentially via AKT signaling promote cell survival proliferation.
Objective: The aim of our study is to analyze the pattern prescription medications used for managing hypertension (HTN) at a tertiary care hospital and assess comorbidities associated with HTN. Methods: This prospective has been conducted duration 6 months in Department Medicine Silchar Medical College Hospital. Prescriptions both genders diagnosed primary essential HTN patients receiving or advised start antihypertensive were included study. Results: One hundred fifty prescriptions have...
Abstract Attenuation of microwaves (up to 30 GHz) around the water vapour absorption line on 22·235 GHz tends persist even after stoppage rain during monsoon season. A theoretical model has been developed for post-rain residual radio waves at (λ = 1·349 cm) by considering vertical transport in region event. The estimate agrees fairly well with that obtained experimentally different events, recorded a radiometer, operating Institute Radio Physics and Electronics, Calcutta University...
Abstract Colorectal cancer (CRC) is a leading cause of cancer-related deaths worldwide. Thus, developing novel and targeted therapies for inhibiting CRC progression metastasis urgent. Several studies, including ours, have reported causal role an upregulated claudin-1 expression in promoting through the activation Src β-catenin-signaling. In murine models colon tumorigenesis, overexpression promotes oncogenic properties such as transformation invasiveness. Conversely, downregulation inhibits...
Abstract Colorectal cancer (CRC) is one of the most leading causes cancer-related death in world because cases are diagnosed advanced stages, when development resistance to chemotherapy more frequent. To face this situation, new therapeutic drugs desperately needed for patients with cancer, but making safe and efficacious remains expensive time consuming. Given high attrition rates, substantial costs slow pace drug discovery further development, repurposing 'old' increasingly becoming an...