A5084883245- Advanced biosensing and bioanalysis techniques
- Electrospun Nanofibers in Biomedical Applications
- Aortic Disease and Treatment Approaches
- Biosensors and Analytical Detection
- Connective tissue disorders research
- CRISPR and Genetic Engineering
- 3D Printing in Biomedical Research
- Mycotoxins in Agriculture and Food
- Tissue Engineering and Regenerative Medicine
- Photonic and Optical Devices
- Diabetic Foot Ulcer Assessment and Management
- Anatomy and Medical Technology
- Wound Healing and Treatments
- Electrochemical Analysis and Applications
- Plant Pathogens and Resistance
- RNA and protein synthesis mechanisms
- Tendon Structure and Treatment
- Osteoarthritis Treatment and Mechanisms
- Aortic aneurysm repair treatments
- Trace Elements in Health
- Angiogenesis and VEGF in Cancer
- Quantum optics and atomic interactions
- Tribology and Lubrication Engineering
- Advanced Biosensing Techniques and Applications
- Insect symbiosis and bacterial influences
The University of Sydney
2018-2025
UNSW Sydney
2019-2023
Native arteries contain a distinctive intima-media composed of organized elastin and an adventitia containing mature collagen fibrils. In contrast, implanted biodegradable small-diameter vascular grafts do not present spatially regenerated, elastin. The elastin-containing structures within the region encompass elastic lamellae (EL) internal lamina (IEL) are crucial for normal arterial function. Here, development novel electrospun graft that facilitates de novo formation structurally...
With the discovery of collateral cleavage activity, CRISPR/Cas12a has recently been identified as a key enabling approach in novel DNA biosensor development. Despite its remarkable success nucleic acid detection, realizing universal CRISPR/Cas biosensing system for non-nucleic targets remains challenging, particularly at extremely high sensitivity ranges analyte concentrations lower than pM level. aptamers can be designed to bind range specific target molecules, such proteins, small and...
Abstract Bioprinting has emerged as a promising technology for fabricating vascularized skin substitutes. The availability of functional tissue constructs is critical the surgical treatment various wounds, including ulcers and burns. Integrating vascular networks within engineered indispensable ensuring adequate nutrient perfusion overall viability. This review undertakes comprehensive exploration application 3D bioprinting constructs. It encompasses an examination printing modalities, ink...
Abstract Synthetic vascular grafts are commonly used in patients with severe occlusive arterial disease when autologous not an option. Commercially available synthetic confronted challenging outcomes: they have a lower patency rate than and currently unable to promote regeneration. Polyglycerol sebacate (PGS), non‐toxic polymer tunable degradation profile, has shown promising results as small‐diameter graft component that can support the formation of neoarteries. In this review, we first...
In order to satisfy the need for sensitive detection of Aflatoxin M1 (AFM1), we constructed a simple and signal-on fluorescence aptasensor based on an autocatalytic Exonuclease III (Exo III)-assisted signal amplification strategy. this sensor, DNA hybridization magnetic nanobeads could be triggered by target AFM1, resulting in release single-stranded induce Exo III-assisted amplification, which numerous G-quadruplex structures would produced then associated with fluorescent dye generate...
Abstract We present a scheme to realize the regulation of single and double transparent windows in two-cavity optomechanical device. By studying output field through device, we not only show transmission spectrum probe second-order sideband process, but also analyze physical mechanism induced transparency window efficiency process. Moreover, optomechanically coupling two cavities resulting are discussed. find that process can be modulated by power control strength between cavities. Our...
Abstract The highly organized extracellular matrix (ECM) of musculoskeletal tissues, encompassing tendons, ligaments and muscles, is structurally anisotropic, hierarchical multi-compartmental. These features collectively contribute to their unique function. Previous studies have investigated the effect tissue-engineered scaffold anisotropy on cell morphology organization for tissue repair regeneration, but arrangement ECM compartmentalization are not typically replicated. Here, we present a...
Wound healing is facilitated by biomaterials-based grafts and substantially impacted orchestrated inflammatory responses that are essential to the normal repair process. Tropoelastin (TE) based materials known shorten period for wound but mechanism of anti-inflammatory performance not known. To explore this, we compared gold standard Integra Dermal Regeneration Template (Integra), polyglycerol sebacate (PGS), TE blended with PGS, in a murine full-thickness cutaneous study. Systemically,...