A5044105204- Dermatologic Treatments and Research
- Insect Resistance and Genetics
- Viral Infectious Diseases and Gene Expression in Insects
- Neurobiology and Insect Physiology Research
- CRISPR and Genetic Engineering
- Virus-based gene therapy research
- Virology and Viral Diseases
- Insect-Plant Interactions and Control
- Genetic Mapping and Diversity in Plants and Animals
- Listeria monocytogenes in Food Safety
- GABA and Rice Research
- Facial Rejuvenation and Surgery Techniques
- Laser Applications in Dentistry and Medicine
- Vascular Malformations and Hemangiomas
- Herpesvirus Infections and Treatments
- Photosynthetic Processes and Mechanisms
- Chromosomal and Genetic Variations
- RNA modifications and cancer
- Reconstructive Facial Surgery Techniques
- Ferroptosis and cancer prognosis
- Nanocomposite Films for Food Packaging
- Plant Molecular Biology Research
- Cytomegalovirus and herpesvirus research
- Epigenetics and DNA Methylation
- Cutaneous Melanoma Detection and Management
Shanghai Ninth People's Hospital
2019-2025
Shanghai Jiao Tong University
2008-2025
Children's Hospital of Zhejiang University
2025
Zhejiang A & F University
2019-2024
Shandong Provincial Hospital
2021-2024
Shandong University
2024
Tianjin Medical University
2015-2024
Wageningen University & Research
2014-2024
State Key Laboratory For Conservation and Utilization of Subtropical Agro-Bioresources
2018-2023
Guangxi University
2018-2023
Some applications, especially those clinical applications requiring high accuracy of sequencing data, usually have to face the troubles caused by unavoidable errors. Several tools been proposed profile quality, but few them can quantify or correct This unmet requirement motivated us develop AfterQC, a tool with functions errors and most them, plus highly automated quality control data filtering features. Different from tools, AfterQC analyses overlapping paired sequences for pair-end data....
Rice leaf morphology is an essential agronomic trait to develop drought-tolerant genotypes for adequate and stable crop production in drought-prone areas. Here, rolled mutant plants were acquired by CRISPR/Cas9-based mutagenesis of Semi-rolled leaf1,2 (SRL1 SRL2) genes, isobaric tags relative absolute quantification (iTRAQ) based proteomic analysis was performed analyze the subsequent regulation events. Homozygous mutants exhibit decreased chlorophyll content, transpiration rate, stomatal...
Abstract Background: Hypertension is 1 of the major global public health challenges, which means that patients with hypertension need more measures to control their blood pressure. Currently, smart phones and applications are developing rapidly, mobile used manage hypertension, but evidences related effectiveness limited. Objective: The purpose was assess impact m-Health apps on pressure control, medication adherence. Methods: 480 participants were randomly assigned intervention groups....
Lysine lactylation (Kla) has recently been reported to participate in regulating transcription human cells. However, the characterization, regulatory mechanism and functional consequence of Kla prokaryotes remain unclear. Here, we report that YiaC functions as a lysine lactylase CobB serves delactylase regulation metabolism. We demonstrate catalyzes addition Kla, while erases this PTM both vitro intracellularly. Moreover, show YdiF can catalyze formation lactyl-coenzyme A, which donates...
Novel rutin-loaded zein-sodium caseinate nanoparticles (ZP) with antioxidant activity in aqueous medium were investigated. The results showed that the sodium concentrations, dosages of rutin and ethanol volume fractions significantly affected zein nanoparticles' characteristics. Concerning properties, highest values loaded ZP obtained using 2, 2-diphenyl-1-picrylhydrazyl scavenging 2 2'-azino-bis (3-ethylbenzothiazoline-6-sulphonic acid) decolourisation assays 52.7% 71.2%, respectively,...
Rice (Oryza sativa L.) is a thermophilic crop vulnerable to chilling stress. However, common wild rice rufipogon Griff.) in Guangxi (China) has the ability tolerate To better understand molecular mechanisms underlying tolerance rice, iTRAQ-based proteomic analysis was performed examine CTS-12, major QTL derived from mediated and recovery-induced differentially expressed proteins (DEPs) between chilling-tolerant line DC90 chilling-sensitive 9311.Comparative identified 206 155 DEPs 9311 DC90,...
Abstract Pulsed dye laser‐resistant port‐wine stains present a therapeutic challenge. The aim of this study was to evaluate the efficacy and safety photodynamic therapy for treating these lesions. A total 67 patients with pulsed cervicofacial were retrospectively assessed after undergoing mediated combination hemoporfin 532‐nm light. For objective evaluation efficacy, first, colorimetric changes in stain lesions evaluated according L * b color coordinate system, then values (Δ E ) blanching...
Many parasites manipulate host behaviour to enhance parasite transmission and survival. A fascinating example is baculoviruses, which often induce death in caterpillar hosts at elevated positions ('tree-top' disease). To date, little known about the underlying processes leading this adaptive manipulation. Here, we show that baculovirus Spodoptera exigua multiple nucleopolyhedrovirus (SeMNPV) triggers a positive phototactic response S. larvae prior causes caterpillars die positions. This...
The herpes simplex virus (HSV)-1 protein pUL21 is essential for efficient replication and dissemination. While has been shown to promote multiple steps of assembly spread, the molecular basis its function remained unclear. Here we identify that a virus-encoded adaptor phosphatase 1 (PP1). directs dephosphorylation cellular proteins, including components viral nuclear egress complex, define conserved non-canonical linear motif in PP1 recruitment. In vitro evolution experiments reveal...
Many parasites enhance their dispersal and transmission by manipulating host behaviour. One intriguing example concerns baculoviruses that induce hyperactivity tree-top disease (i.e., climbing to elevated positions prior death) in caterpillar hosts. Little is known about the underlying mechanisms of such parasite-induced behavioural changes. Here, we studied role ecdysteroid UDP-glucosyltransferase (egt) gene Spodoptera exigua multiple nucleopolyhedrovirus (SeMNPV) S. larvae. Larvae infected...
Both nonablative fractional (NAFL) laser combined with intense pulsed light (IPL) and picosecond alexandrite (PSAL) diffractive lens array (DLA) have been documented for their efficacy in facial rejuvenation. To observe the safety of PSAL-DLA IPL-NAFL rejuvenation Chinese individuals. Each subject (n = 18) received three treatments on half face, 1-month interval between treatments. One side face was randomly treated PSAL-DLA, other IPL-NAFL. Quantitative data wrinkles, pores, brown spots,...
AIM: To compare analysis of the impact high altitude on corneal endothelial cells, and prognosis in patients with cataract surgeries. METHODS: Totally 265 plateau surgeries performed between January 2019 July 2022 (average altitude=3000 m), 524 plain 2020 were included. The propensity score matching (PSM) method was applied to match basic information both regions a 1:1 basis. Corneal cell density (ECD), coefficient variation (CV), hexagonal ratio (HEX), duration surgery, pre- postoperative...
Abstract Background Despite ongoing advancements in medical aesthetics, there remains a lack of consensus regarding standardized postoperative care protocol following laser treatment for skin pigmentation disorders. Objectives To evaluate the influence facial cleansing practices on efficacy and safety therapy among patients diagnosed with pigmentary diseases. Methods Thirty pigmented lesions (freckles and/or solar lentigines) were randomly allocated to two distinct groups. Following 755-nm...
Background: Deep-brain stimulation (DBS) is increasingly being used to treat a variety of neuropsychiatric conditions, many which exhibit idiosyncratic symptom presentations and neural correlates across individuals. Methods: Eleven patients (chronic pain=5, major depressive disorder=5, obsessive-compulsive disorder=1) underwent inpatient testing using stereoelectroencephalography (sEEG) monitoring identify personalized targets for subsequent DBS implantation. We present structured approach...
Development of high yielding and more palatable glutinous rice is an important goal in breeding long-standing cultural interaction Asia. In this study, the TGW6 Wx, major genes conferring 1000 grain weight (GW) amylose content (AC), were edited a maintainer line by CRISPR/Cas9 technology. Four targets assembled pYLCRISPR/Cas9Pubi-H vector T0 mutant plants obtained through Agrobacterium mediated transformation with 90% mutation frequency having 28% homozygous mutations without off-target...
Neuroparasitism concerns the hostile take-over of a host's nervous system by foreign invader, in order to alter behaviour host favour parasite. One most remarkable cases parasite-induced behavioural manipulation comprises changes baculoviruses induce their caterpillar hosts. Baculoviruses may manipulate two ways: hyperactivity (increased movement horizontal plane) and/or tree-top disease (movement elevated levels vertical plane). Those are followed liquefaction and death caterpillar. In...
Histone modifications are typically recognized by chromatin-binding protein modules (referred to as 'readers') mediate fundamental processes such transcription. Lysine β-hydroxybutyrylation (Kbhb) is a new type of histone mark that couples metabolism gene expression. However, the readers prefer Kbhb remain elusive. This knowledge gap should be filled in order reveal molecular mechanism this epigenetic regulation. Herein, we developed chemical proteomic approach, relying upon multivalent...