A5100671986- Cardiac Arrest and Resuscitation
- Thyroid Disorders and Treatments
- Thyroid Cancer Diagnosis and Treatment
- Autophagy in Disease and Therapy
- Thermal Regulation in Medicine
- Traumatic Brain Injury and Neurovascular Disturbances
- Neonatal and fetal brain pathology
- Anesthesia and Neurotoxicity Research
- Vitamin D Research Studies
- Mechanical Circulatory Support Devices
- Pediatric health and respiratory diseases
- Hormonal Regulation and Hypertension
- Neurological Disease Mechanisms and Treatments
- Cardiac Ischemia and Reperfusion
- Cardiac electrophysiology and arrhythmias
- MicroRNA in disease regulation
- Atherosclerosis and Cardiovascular Diseases
- Apelin-related biomedical research
- Nosocomial Infections in ICU
- Heart Rate Variability and Autonomic Control
- Pneumonia and Respiratory Infections
- Antibiotic Resistance in Bacteria
- Adipose Tissue and Metabolism
- Neuroscience of respiration and sleep
- Pancreatic function and diabetes
Shanghai Public Health Clinical Center
2025
Huashan Hospital
2025
Tianjin Medical University General Hospital
2010-2024
Sun Yat-sen University
2015-2024
The First Affiliated Hospital, Sun Yat-sen University
2015-2024
Taiyuan University of Technology
2024
Longhua Hospital Shanghai University of Traditional Chinese Medicine
2024
Southern University of Science and Technology
2022-2024
People's Hospital of Cangzhou
2023-2024
Shanghai Guanghua Hospital of Integrated Traditional Chinese and Western Medicine
2024
The frequency of antimicrobial resistance has increased globally due to misuse and overuse antibiotics, multi-drug resistant (MDR) bacteria are now recognized as a major cause hospital-acquired infections (HAI). Our aim was investigate the prevalence, distribution, susceptibility rates MDR in patients with HAI from tertiary hospital China. We retrospectively evaluated all confirmed diagnosis bacterial infection at general Jining, for period between January 2012 December 2014. following...
OBJECTIVE:Recent studies have shown that circulating microRNAs might be useful, novel biomarkers for the diagnosis of acute myocardial infarction.The aims this study were to evaluate expression cardiacspecific miRNAs (miR-1, -133a, -208b, and -499) in patients with infarction compare diagnostic values these cardiac troponin T. METHODS: Sixty-seven plasma samples obtained from 32 specimens collected healthy volunteers analyzed study.The levels cardiac-specific measured by quantitative reverse...
Trace elements, such as iodine and selenium, are closely related to autoimmune thyroiditis thyroid function. Low serum magnesium is associated with several chronic diseases; however, its associations function unclear. We investigated the relationships between low magnesium, thyroiditis, in 1,257 Chinese participants. Demographic data were collected via questionnaires, levels of stimulating hormone, anti-thyroid peroxidase antibody, anti-thyroglobulin antibody (TGAb), free thyroxine, iodine,...
In moiré crystals resulting from the stacking of twisted two-dimensional (2D) layered materials, a subtle adjustment in twist angle surprisingly gives rise to wide range correlated optical and electrical properties. Herein, we report synthesis supertwisted WS2 spirals observation giant second harmonic generation (SHG) these spirals. Supertwisted featuring different angles are synthesized on Euclidean or step-edge particle-induced non-Euclidean surface using carefully designed water-assisted...
Selective serotonin reuptake inhibitors (SSRIs) and norepinephrine (SNRIs) are reported to cause stress cardiomyopathy (SC). This study evaluated the association between SSRI/SNRI use occurrence of in publicly available U.S. Food Drug Administration Adverse Event Reporting System (FAERS) database. Disproportionate analysis likelihood ratio tests were used identify risk associated with SSRIs or SNRIs incidence SC, using data from 2012 2022 acquired FAERS The identified 132 individual case...
Objective To investigate the effects of Cushing’s disease (CD) and adrenal-dependent syndrome (ACS) on bone mineral density (BMD) metabolism. Methods Data were retrospectively collected for 55 patients with hypercortisolism (CD, n = 34; ACS 21) from January 1997 to June 2014. BMD was examined in all patients, turnover markers tested some patients. Healthy controls (n 18) also recruited. Results The lumbar spine femoral neck significantly lower CD groups than control group. Lumbar collagen...
Abstract Background HBV integration is considered as the main contributor to hepatocellular carcinoma (HCC). However, whether integrated sequences determine genotype pathogenicity and how block their function during HCC progression remains unclear. Methods An in vitro HBV-infected PHH model liver cancer cell lines were established confirm pathogenic potential of HBV-SITEs. The roles HBV-SITE-1 development analyzed using cellular phenotypic assays molecular biology techniques, including...
Cervical lymph node metastasis in papillary thyroid carcinoma (PTC) affects the treatment and prognosis of patients. Ultrasound is a common imaging method for detecting cervical nodes PTC patients; however, it not accurate determining metastasis.To evaluate value contrast-enhanced ultrasound combined with elastography evaluating PTC.A total 94 patients were recruited. According to pathological results, divided into two groups: metastatic group (n = 50) reactive 63). The routine findings,...
Abstract Mild hypothermia treatment (MHT) improves the neurological function of cardiac arrest (CA) patients, but exact mechanisms recovery remain unclear. Herein, we generated a CA and cardiopulmonary resuscitation (CPR) mouse model to elucidate such function. Naïve mice were randomly divided into two groups, normothemia (NT) group, in which animals had normal body temperature, MHT temperature 33 °C (range: 32–34 °C), after return spontaneous circulation (ROSC), followed by CA/CPR....
Abstract Background Several heart failure (HF) risk models exist, however, most of them perform poorly when applied to real-world situations. This study aimed develop a convenient and efficient model identify patients with high readmission within 90 days HF. Methods A multivariate logistic regression was used predict the 90-day readmission. Data were extracted from electronic medical records January 1, 2017 December 31, follow-up HF 3 months after discharge. Model performance evaluated using...
Background. This study was to explore the pharmacokinetics of saxagliptin (Sax) in Goto-Kakizaki (GK) rats complicated with depression induced by chronic unpredicted mild stress (CUMS). The comorbidity diabetic patients is becoming more and epidemic. Whether mental disorder alters hypoglycemic drugs diabetes not clear. Methods. Five-week-old male GK were kept cage for 7 weeks a specific pathogen free (SPF)-grade lab until emergence then divided into two groups: control group model group....
Substantial morbidity and mortality are associated with postcardiac arrest brain injury (PCABI). MicroRNAs(miRNAs) essential regulators of neuronal metabolism processes have been shown to contribute alleviated neurological after cardiac arrest. In this study, we identified miRNAs related the prognosis patients dysfunction cardiopulmonary resuscitation based on data obtained from Gene Expression Omnibus (GEO) database. Then, explored effects miR-483-5p mitochondrial biogenesis,...
Abstract Coronary heart disease (CHD) is the result of a complex metabolic disorder caused by various environmental and genetic factors, often has anxiety as comorbidity. Rupture atherosclerotic plaque in CHD patients can lead to acute coronary syndrome (ACS). Anxiety known independent risk factor for adverse cardiovascular events mortality ACS, but it remains unclear how stress-induced behavior impacts their blood plasma metabolome contributes worsening CHD. The present study aimed...
// Hongyan Wei 1, 2, * , Ting Zhou Boyu Tan 2 Lei Zhang 3 Mingming Li 1 Zhijun Xiao and Feng Xu Fengxian Hospital, Southern Medical University, Shanghai, China Hunan Provincial People’s Normal Changsha, Joint Research Center for Translation Medicine, East These authors have contributed equally to this work Correspondence to: Xu, email: andrewfxu1998@gmail.com Keywords: chronic unpredicted mild stress(CUMS), depression, repaglinide, drug-metabolizing enzymes (DMEs), glucocorticoid...
Abstract Background Alpha‐fetoprotein (AFP) has received extensive attention in the differential diagnosis of hepatocellular carcinoma (HCC), especially for AFP‐negative HCC (AFP‐NHCC). The current study aimed to explore value targeted regulation LHPP expression‐related microRNAs (miRs) and protein induced by vitamin K deficiency or antagonist‐II (PIVKA‐II) AFP‐NHCC. Methods A retrospective was conducted on a testing set—including 214 AFP‐NHCC patients, 200 cirrhosis, 210 controls,...
<b><i>Objectives:</i></b> The reference values for thyroid volume (Tvol) determined by ultrasound require supportive data of normal Tvol from local iodine-sufficient populations. This study aimed to explore new in Chinese adults and comprehensively evaluate the factors associated with enlarged Tvol. <b><i>Methods:</i></b> A cross-sectional was conducted Tianjin, China. measured long-term iodine sufficiency. Blood urine samples were collected...