- Sinusitis and nasal conditions
- Antifungal resistance and susceptibility
- Tracheal and airway disorders
- Infectious Diseases and Mycology
- Head and Neck Surgical Oncology
- Airway Management and Intubation Techniques
- Meningioma and schwannoma management
- Salivary Gland Tumors Diagnosis and Treatment
- Otolaryngology and Infectious Diseases
- Fungal Infections and Studies
- Legionella and Acanthamoeba research
- Botulinum Toxin and Related Neurological Disorders
- Cervical and Thoracic Myelopathy
- Streptococcal Infections and Treatments
- Hospital Admissions and Outcomes
- Reconstructive Surgery and Microvascular Techniques
- Trauma Management and Diagnosis
- Neutrophil, Myeloperoxidase and Oxidative Mechanisms
- Emergency and Acute Care Studies
- Bone Tumor Diagnosis and Treatments
- Spine and Intervertebral Disc Pathology
- Tumors and Oncological Cases
- Congenital Diaphragmatic Hernia Studies
- Spinal Fractures and Fixation Techniques
- Oral Health Pathology and Treatment
Massachusetts Eye and Ear Infirmary
2022-2024
Harvard University
2024
University of California, San Francisco
2012-2023
Abstract Background During the SARS‐CoV‐2 pandemic, tracheostomy may be required for COVID‐19 patients requiring long‐term ventilation in addition to other conditions such as airway compromise from head and neck cancer. As an aerosol‐generating procedure, increases exposure of health care workers infection. Performing surgical requires a strategy that mitigates these risks maintains quality patient care. Methods This study is multidisciplinary review institutional guidelines clinical...
A 68-year-old immunocompromised man with rhino-orbital-cerebral mucormycosis was treated retrobulbar injections of amphotericin B deoxycholate in conjunction intravenous antifungals and endoscopic sinus debridement. Transient episodes orbital inflammation were noted after injections, but progression infection halted visual acuity restored eventual hospital discharge. To the authors' knowledge, clearance has not been previously reported. This intervention may be a viable therapeutic option...
To evaluate our initial experience with a novel technique, endoscopic anterior maxillotomy (EAM), for improved access to the anterior-lateral skull base. Clinical and radioanatomic data are presented describe define this technique.Case series.Surgical patients lesions of pterygopalatine fossa, infratemporal maxilla treated from 2006 2008 reviewed. Demographic surgical technique presented. A analysis pre- post-EAM is performed increased access. Matched-paired was statistical...
Objectives/Hypothesis To define a new clinical hospitalist practice paradigm originating at the University of California, San Francisco. Design Retrospective administrative database review tertiary referral hospital. Materials and Methods A consortium model an otolaryngologist was developed. Billing records, including Current Procedural Terminology (CPT) International Classification Disease‐9 (ICD‐9) codes, were reviewed to evaluate number type consultations surgeries generated during 2‐year...
PurposeTo identify initial, preintervention magnetic resonance imaging (MRI) findings that are predictive of visual and mortality outcomes in acute invasive fungal rhinosinusitis (AIFRS).DesignRetrospective cohort study.ParticipantsPatients with histopathologically or microbiologically confirmed AIFRS cared for at a single, tertiary academic institution between January 2000 February 2020.MethodsA retrospective review MRI scans clinical records patients diagnosis was performed. For each...
Abstract BACKGROUND: Surgical access to Meckel's Cave (MC) is challenging due its deep location and surrounding important neurovascular structures. Currently existing endoscopic endonasal (EE) approaches require dissecting near the internal carotid artery (ICA) or transposition of pterygopalatine bundle. OBJECTIVE: To describe a novel approach anterolateral aspect MC using minimally invasive EE route. METHODS: The transmaxillary transinferior orbital fissure was simulated in 10 specimens....
Acute invasive fungal sinusitis (AIFS) is an aggressive and dangerous disease of the paranasal sinuses with high morbidity mortality. The immune response at level nasal mucosa, site entry, has not been previously evaluated.To evaluate differential gene expression in sinonasal mucosa AIFS patients as compared to control using RNA sequencing.Sinonasal tissue samples were prospectively obtained from consenting undergoing surgery between November, 2020 2021. extraction sequencing performed was...
Objective To report on the incidence of dysphagia, dysphonia, and acute vocal fold motion impairment (VFMI) following revision anterior cervical spine surgery, as well to identify risk factors associated with VFMI in immediate postoperative period. Study Design Retrospective cohort study. Setting Tertiary care center. Subjects Methods All patients who underwent 2‐team reoperative discectomy fusion (ACDF) were retrospectively reviewed. Incidence was noted. Patient operative evaluated for...
Otolaryngologists commonly evaluate patients with findings suspicious for deep space soft tissue infections of the neck. In this case, a woman history injection drug use (IDU) presented dysphagia, odynophagia, and neck pain. Multiple abscesses, too small to drain, were seen on imaging. Despite broad-spectrum intravenous antibiotics, she unexpectedly rapidly developed respiratory failure requiring intubation. Further work-up diagnosed wound botulism (WB). To our knowledge, is first report WB...
Invasive facial fungal infections affect the orofacial soft tissues in immunocompromised patients and can cause significant morbidity mortality. Primary infection occurs from direct inoculation of skin surface, while secondary extension an adjacent sinonasal process. The imaging features are similar to acute fulminant invasive sinusitis with infiltration combination disease. However, primary occur absence disease, making diagnosis challenging. We present two cases, one infection. Careful...
Dual island “paddle flaps” first described by Yu et al have demonstrated great utility in pharyngoesophageal and anterior neck reconstruction.[1] These fasciocutaneous flaps are tubed for the reconstruction a separate paddle is used external skin Doppler monitoring. This technique has also found success treating pharyngocutaneous fistulas.[2] Two case series good clinical functional results with minimal morbidity using anterolateral thigh (ALT) dual complex pharyngoesophageal, tracheal,...
Abstract We report a liver transplant patient with disseminated Legionella micdadei infection pulmonary, laryngeal, and suspected muscle involvement. This organism, which stains weakly acid‐fast, primarily affects immunocompromised patients. The diagnosis is difficult to make; in this case, the organism was identified via molecular diagnostics on laryngeal pulmonary biopsy tissue.