Bo Yu

ORCID: 0000-0002-0722-0968
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About
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Research Areas
  • Ethics in Clinical Research
  • Electronic Health Records Systems
  • Biomedical Text Mining and Ontologies
  • Biomedical Ethics and Regulation
  • Cardiomyopathy and Myosin Studies
  • Biochemical effects in animals
  • Access Control and Trust
  • Sirtuins and Resveratrol in Medicine
  • Traditional Chinese Medicine Analysis
  • Photoreceptor and optogenetics research
  • Biomedical and Engineering Education
  • Seaweed-derived Bioactive Compounds
  • Alkaloids: synthesis and pharmacology
  • Cardiovascular Issues in Pregnancy
  • Helicobacter pylori-related gastroenterology studies
  • Metabolism, Diabetes, and Cancer
  • Electron Spin Resonance Studies
  • Protein Tyrosine Phosphatases
  • Law, AI, and Intellectual Property
  • Mechanical Failure Analysis and Simulation
  • Coronary Artery Anomalies
  • Saffron Plant Research Studies
  • Neuroscience and Neuropharmacology Research
  • Mechanical Engineering and Vibrations Research
  • Biosimilars and Bioanalytical Methods

Huazhong University of Science and Technology
2018-2025

Central Hospital of Wuhan
2025

George Mason University
2015-2022

Tongji Hospital
2018-2021

Zhengzhou University
2021

Shanghai University of Traditional Chinese Medicine
2013-2019

Air Force Medical University
1990-2017

Xijing Hospital
2015-2017

Liaocheng People's Hospital
2016

Xihua University
2015

Sirtuins are a family of highly evolutionarily conserved nicotinamide adenine nucleotide-dependent histone deacetylases. Sirtuin-3 (SIRT3) is member the sirtuin that localized primarily to mitochondria and protects against oxidative stress-related diseases, including myocardial ischemia/reperfusion (MI/R) injury. Melatonin has favorable effect in ameliorating MI/R We hypothesized melatonin injury by activating SIRT3 signaling pathway. In this study, mice were pretreated with or without...

10.1111/jpi.12419 article EN Journal of Pineal Research 2017-05-13

Berberine (BBR) exerts potential protective effect against myocardial ischemia/reperfusion (MI/R) injury. Activation of silent information regulator 1 (SIRT1) signaling attenuates MI/R injury by reducing oxidative damage and inflammation response. This study investigated the antioxidative anti‐inflammatory effects BBR treatment in condition elucidated its mechanisms. Sprague‐Dawley rats were treated with absence or presence SIRT1 inhibitor sirtinol (Stnl) then subjected to conferred...

10.1155/2016/1689602 article EN cc-by Oxidative Medicine and Cellular Longevity 2015-12-14

The retina is a light-sensitive tissue of the central nervous system that vulnerable to ischemia. pathological mechanism underlying retinal ischemic injury not fully understood. purpose this study was investigate structural and functional changes different types rat neurons visual behavior following transient global Retinal ischemia induced using 4-vessel occlusion model. Compared with normal group, number βIII-tubulin positive ganglion cells calretinin amacrine were reduced from 6 h 48...

10.1371/journal.pone.0065555 article EN cc-by PLoS ONE 2013-06-11

Cardiovascular disease has been established as a major cause of morbidity and mortality worldwide, resulting in huge burden to patients, families, society. Traditional Chinese Medicine (TCM) presents several advantages for the prevention treatment cardiovascular diseases including multitargets, multi-ingredients, fewer side effects, low cost. In this study, rat model myocardial infarction (MI) was by ligating anterior descending branch left coronary artery, effect Taohong Siwu decoction...

10.1155/2019/5198278 article EN cc-by Cardiology Research and Practice 2019-12-10

Purpose Cardiac hypertrophy is a critical contributor to heart failure. Therapies that effectively manage cardiac are still inadequate. Crocin natural component of saffron, and its beneficial properties have been previously documented. This study aimed investigate the role crocin in apoptosis related mechanisms. Methods Sprague-Dawley rats were infused with angiotensin II (Ang II; 520 ng/kg/min) or normal saline then intraperitoneally injected (40 mg/kg) dimethyl sulfoxide for 4 weeks....

10.3138/cim-2024-0118 article EN Clinical and investigative medicine 2025-03-01

Although studies have identified hundreds of genetic variants associated with asthma risk, a large fraction heritability remains unexplained, especially in Chinese individuals.To identify risk factors for Han population, 211 asthma-related genes were first selected based on database searches. The then sequenced subjects Discovery Cohort (284 patients and 205 older healthy controls) using targeted next-generation sequencing. Bioinformatics analysis statistical association analyses performed...

10.1002/jcla.23813 article EN cc-by-nc-nd Journal of Clinical Laboratory Analysis 2021-05-09

Informed consents, either for treatment or use/disclosure, that protect the privacy of patient information subject to law in certain circumstances may override wishes, are mandatory practice healthcare. Although healthcare industry has widely adopted Electronic Medical Record (EMR) systems, consents still obtained and stored primarily on paper scanned electronic documents. Integrating a consent management system into an EMR involves various implementation challenges. The authors show how can...

10.4018/ijrqeh.2015010103 article EN International Journal of Reliable and Quality E-Healthcare 2015-01-01

Head-feed combine harvester transaxle transmits motive force to the header and driving system, with adverse working conditions is especially prone failure.It not easy detective recognize faults of traditional diagnostic methods as "Listening, Observation Touch", because it has complex inner structures, number meshing gears.In order find fault components distinguish failure types, analyzing vibration signal transaxle.In present paper, signals a certain type head-feed are extracted by SENDIG...

10.2991/icmmita-15.2015.274 article EN cc-by-nc Advances in computer science research 2015-01-01

Radial artery pulse wave is a very important biological signal in the Traditional Chinese Medical (TCM) theory. It also plays an role field of health informatics. In this paper, we proposed new shiatsu three-part collection method based on TCM to collect pulses objectively. We established feasible for collection, and provided objective process radial collection. The result research can be applied disease diagnosis

10.1109/bibm.2013.6732686 article EN 2013-12-01

Biopharmaceutical production systems and processes are vulnerable to cyberattacks from sophisticated adversaries. Therefore, it is imperative start building biopharmaceutical manufacturing that offer verifiable formalism transform the current state of security across all stages.

10.1109/msec.2022.3160465 article EN IEEE Security & Privacy 2022-06-02

Beef is one of the widely consumed protein sources in world, so safety and quality beef have been great concern globally. Recently, cold plasma has developed as a novel non-thermal, cost-effective eco-friendly food processing technology applied sterilization. Helium (He) air are used working gas plasma. Although antimicrobial effects He against pathogens on meats extensively investigated, comparison their especially for influence rarely studied.

10.1109/icops36761.2021.9588518 article EN 2020 IEEE International Conference on Plasma Science (ICOPS) 2021-09-12
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