A5102940765- Biochemical effects in animals
- Nitric Oxide and Endothelin Effects
- Traumatic Brain Injury and Neurovascular Disturbances
- Vitamin C and Antioxidants Research
- Exercise and Physiological Responses
- Adipose Tissue and Metabolism
- Sulfur Compounds in Biology
- Intracranial Aneurysms: Treatment and Complications
- Hydrogen's biological and therapeutic effects
- Sexual function and dysfunction studies
- Muscle metabolism and nutrition
- Thermal Regulation in Medicine
- Spinal Cord Injury Research
- Inhalation and Respiratory Drug Delivery
- Phytochemical and Pharmacological Studies
- Glioma Diagnosis and Treatment
- Parasitic Infections and Diagnostics
- Intracerebral and Subarachnoid Hemorrhage Research
- Hormonal and reproductive studies
- High Altitude and Hypoxia
- Nanoplatforms for cancer theranostics
- Urinary Bladder and Prostate Research
- Cardiac Arrest and Resuscitation
- Bee Products Chemical Analysis
- Cancer, Hypoxia, and Metabolism
Istanbul University-Cerrahpaşa
1999-2021
Istanbul University
2002-2015
The ever increasing use of cellular phones and the number associated base stations are becoming a widespread source nonionizing electromagnetic radiation. Some biological effects likely to occur even at low-level EM fields. In this study, gigahertz transverse (GTEM) cell was used as an exposure environment for plane wave conditions far-field free space field propagation GSM transceiver station (BTS) frequency 945 MHz, on oxidative stress in rats were investigated. When fields power density...
Physical training is known to induce oxidative stress in individuals subjected intense exercise. In this study, we investigated plasma malondialdehyde (MDA) levels and erythrocyte superoxide dismutase (SOD) activity of 25 young male footballers a control group similar age. Red blood cell (RBC) count, haemoglobin (Hb) haematocrit (Hct) values, copper (Cu) zinc (Zn) were also examined. The maximal oxygen uptake (VO2max) all subjects was determined order establish their functional capacity....
The aim of this study was to explore whether levels intercellular adhesion molecule-1 (ICAM-1) and vascular cell (VCAM-1) are elevated in the cerebrospinal fluid (CSF) serum patients after aneurysmal subarachnoid hemorrhage (SAH).This prospective clinical focused on 21 who had recently suffered an SAH due rupture 15 control with hydrocephalus no other central nervous system disease. Cerebrospinal samples obtained within first 3 days 5th 7th were assayed for ICAM-1 VCAM-1 by using...
Sildenafil, a selective and potent inhibitor of cyclic guanosine monophosphate (cGMP)-specific phosphodiesterase (PDE)5, has relaxant effect on the smooth muscle cells arterioles supplying human corpus cavernosum acting via nitric oxide (NO)-dependent mechanism. This study aimed to investigate possible protective sildenafil citrate extent tissue integrity, oxidant-antioxidant status neutrophil infiltration inflamed organ in rat model acetic acid-induced colitis.Colitis was induced by...
To compare the frequency of apoptosis in erectile tissue chronic diabetic and healthy rats.Fourteen 10 Sprague-Dawley rats were killed, their penises harvested stored at -70 degrees C until staining flow cytometric analysis for apoptosis. A cell suspension was obtained from penile by scraping inside cavernosum with a scalpel filtering through mesh. Samples (0.5 x 106 cells) stained Annexin V (an indicator apoptosis) propidium iodide (PI, which stains dead cells), incubated 15 min room...
Administration of streptozotocin (STZ) was used to induce diabetes, as the mechanism involved is believed associated with generation free radicals. Supplementation antioxidant molecules such melatonin may serve a protection against diabetes. The aim this study determine whether STZ-induced effects on plasma thiobarbituric acid-reactive substances (TBARS, marker lipid peroxidation) and total sialic acid levels could be blocked by melatonin. STZ significantly increased TBARS. Treatment...
Experimental studies provide evidence that oxidative damage plays a role in the development of vasospasm after aneurysmal subarachnoid hemorrhage (SAH) but data from human is still limited. The purpose this study was to investigate time course cerebrospinal fluid (CSF) superoxide dismutase (SOD) and serum malondialdehyde (MDA) changes patients with SAH.SOD CSF MDA were detected on days 1-3, 5 7 SAH 21 patients, results compared 15 hydrocephalus. also those clinical parameters including...
Thyroid hormones are associated with the oxidative and antioxidative status of organism. Depression metabolism by hypothyroidism has been reported to decrease oxidant production thus protect tissues against damage. The purpose present study was investigate Zn Cu levels in MMI-induced show whether there is a connection between these trace elements oxidant-antioxidant experimental hypothyroidism. 3-Nitrotyrosine measured as marker nitro-oxidative stress. In order examine antioxidant rats, GSH...
Abstract Background: Previous studies have suggested the importance of redox regulation in carcinogenesis. The aim this study was to evaluate prognostic role altered homeostasis and oxidative DNA damage patients with breast carcinoma before during two cycles chemotherapy. Methods: This included 30 whose serum samples were obtained on admission treatment, after first second chemotherapy, 20 controls. We investigated total antioxidant status (TAS), thiobarbituric acid reacting substances...