Muhammad Usama Mazhar

ORCID: 0000-0002-0748-5421
Publications
Citations
Views
---
Saved
---
About
Contact & Profiles
Research Areas
  • Pharmacological Effects of Natural Compounds
  • X-ray Diffraction in Crystallography
  • Crystallization and Solubility Studies
  • Computational Drug Discovery Methods
  • Natural product bioactivities and synthesis
  • Antimicrobial Peptides and Activities
  • Inorganic Chemistry and Materials
  • Healthcare and Venom Research
  • Corrosion Behavior and Inhibition
  • Big Data and Business Intelligence
  • CRISPR and Genetic Engineering
  • Protein Hydrolysis and Bioactive Peptides
  • Gastrointestinal motility and disorders
  • Pharmaceutical Practices and Patient Outcomes
  • Organometallic Compounds Synthesis and Characterization
  • Veterinary medicine and infectious diseases
  • Exercise and Physiological Responses
  • Rheumatoid Arthritis Research and Therapies
  • Schizophrenia research and treatment
  • Probiotics and Fermented Foods
  • Iron-based superconductors research
  • Dermatology and Skin Diseases
  • BRCA gene mutations in cancer
  • Medication Adherence and Compliance
  • Heusler alloys: electronic and magnetic properties

Quaid-i-Azam University
1996-2025

Islamia University of Bahawalpur
2024

Government College University, Faisalabad
2024

CMH Lahore Medical College and Institute of Dentistry
2020-2022

National University of Medical Sciences
2020

Combined Military Hospital
2020

Dysbiosis of gut microbiota and loss gut-barrier integrity contribute to the development severity rheumatoid arthritis (RA). The available treatments pose a burden major adverse effects new treatment strategies are therefore need time. In this study, Pediococcus acidilactici NMCC-B (Probiotic) was evaluated for its safety efficacy in complete Freund’s adjuvant (CFA)-induced mice model RA. Mice were treated with either Escherichia coli (1 × 10 9 CFU/ml) or P. CFU/ml, 2 assess acute,...

10.1371/journal.pone.0324060 article EN cc-by PLoS ONE 2025-05-22

Introduction Astragalus species have been widely used in Chinese herbal medicine to treat gastrointestinal and inflammatory disorders. This study was conducted evaluate the efficacy of sarcocolla (ASE) rationalize its medicinal use as an antispasmodic drug for treatment spasmodic disorders associated with increased intestinal motility. Methods The ethanolic extract ASE studied examine effect on isolated rabbit ileum preparations, contractions were recorded PowerLab (ADInstruments, Sydney,...

10.7759/cureus.9066 article EN Cureus 2020-07-08

In the current study, it is aimed to scrutinize physical properties of LiBeX (X = Sb, Bi) compounds in detail. Density‐functional‐theory‐based WIEN2k and Vienna Ab initio Simulation Package, employing generalized gradient approximation Perdew–Burke–Ernzerhof, Wu–Cohen, Tran–Blaha‐modified Becke–Johnson (TB‐mBJ) exchange‐correlation schemes, are utilized better validate outcomes. The exhibit energetic, lattice dynamic, mechanical stability. Electronic structure calculations using TB‐mBJ...

10.1002/pssb.202400392 article EN physica status solidi (b) 2024-10-25

Rasagiline, a drug for Parkinson's disease is metabolized by CYP1A2 enzyme. The objective of the study was to investigate influence cytochrome P450 1A2 variants and smoking status healthy individuals on pharmacokinetics rasagiline.A comparative, open label, interventional, single oral dose, pharmacokinetic performed 108 volunteers in UHS & UVAS, Lahore. Data collection initiated June 2016 ended January 2018. It divided three phases with 1, 2 5mg rasagiline given group 36 each phase....

10.12669/pjms.38.3.4940 article EN cc-by Pakistan Journal of Medical Sciences 2022-01-19

Abstract The complex, [Cu(dmap)(OAc)(H 2 O)] · 2H O (dmap = N,N -dimethylaminopropanolato, OAc acetato) was synthesized by drop-by-drop addition of -dimethylaminopropanol to copper(II) acetate dihydrate suspended in toluene. blue crystalline product characterized its melting point, elemental analysis, infrared spectral study, mass thermal analysis and the single-crystal X-ray structure analysis. Compound ( 1 ) crystalizes triclinic space group, P ̄1, a 6.3716(9) Å, b 8.2719(12) c 10.9254(16)...

10.1515/zkr.i-2013-1693 article EN Zeitschrift für Kristallographie - Crystalline Materials 2014-01-01

Rheumatoid arthritis is a lifelong disease with swelling, synovial hyperplasia, production of autoantibodies, and joint deformity contributing to the dysfunction. The available treatments have major side effects, so, new pharmacological treatment strategies would be welcome. Recently, Pediococcus acidilactici NMCC-B used in attenuating inflammation associated CFA-induced mice model proved better alternative no toxicity profile. Evidence suggested that dysbiosis gut microbiota loss...

10.2139/ssrn.4407891 preprint EN 2023-01-01

The mechanism of the fluxional process occurring in dimeric tetraorganodicarboxylato stannoxanes is presented on basis multinuclear NMR studies carried out noncoordinating solvents. This a consequence rapid migration carboxylate groups from one tin atom to other. It has been proposed that larger carboxylates will also execute this behavior. effect cis and trans positions discussed. very fast could not be stopped even at low temperatures, as measured time scale. © 1996 John Wiley & Sons, Inc.

10.1002/(sici)1098-1071(199608)7:4<233::aid-hc4>3.3.co;2-s article EN Heteroatom Chemistry 1996-08-01
Coming Soon ...