A5086825568- Nanoparticles: synthesis and applications
- Essential Oils and Antimicrobial Activity
- Phytochemicals and Antioxidant Activities
- Bacterial Identification and Susceptibility Testing
- Pomegranate: compositions and health benefits
- Medicinal Plants and Neuroprotection
- Advanced Nanomaterials in Catalysis
- Bee Products Chemical Analysis
- Graphene and Nanomaterials Applications
- Moringa oleifera research and applications
- Medicinal Plant Research
- Protein Hydrolysis and Bioactive Peptides
- Streptococcal Infections and Treatments
- Microbial Metabolic Engineering and Bioproduction
- Infective Endocarditis Diagnosis and Management
- Selenium in Biological Systems
- Medical and Biological Ozone Research
- Mycorrhizal Fungi and Plant Interactions
- Chemotherapy-induced organ toxicity mitigation
- Probiotics and Fermented Foods
- Antimicrobial Resistance in Staphylococcus
- Seed and Plant Biochemistry
- Plant Parasitism and Resistance
- Seaweed-derived Bioactive Compounds
- Synthesis and Biological Evaluation
King Abdulaziz University
2017-2025
King Abdulaziz Hospital
2020-2023
King Abdul Aziz University Hospital
2014-2021
Karolinska Institutet
2013-2020
Karolinska University Hospital
2013-2016
ABSTRACT The FilmArray platform (FA; BioFire, Salt Lake City, UT) is a closed diagnostic system allowing high-order multiplex PCR analysis with automated readout of results directly from positive blood cultures in 1 h. In the present study, we evaluated clinical performance culture identification (BCID) panel, which includes 19 bacteria, five yeasts, and three antibiotic resistance genes. total, 206 bottles were included study. could identify microorganisms 153/167 (91.6%) samples...
Background: The Pfizer-BioNTech COVID-19 vaccine has recently received emergency approval from the US FDA. mRNA technology was used to manufacture Pfizer vaccine; however, as a pioneering that never been in of vaccines, many people have concerns about vaccine's side effects. Thus, current study aimed track short-term effects vaccine. Methods: information this gathered by Google Form-questionnaire (online survey). results included responses 455 individuals, all whom are Saudi Arabia...
The medicinal administration of Aloe vera gel has become promising in pharmaceutical and cosmetic applications particularly with the development nanotechnology concept. Nowadays, effective H. pylori treatment is a global problem; therefore, natural products nanopolymers such as chitosan nanoparticles (CSNPs) could represent novel strategy for gastric infection pylori. HPLC analysis A. indicated presence chlorogenic acid main constituent (1637.09 µg/mL) other compounds pyrocatechol µg/mL),...
The toxicity of the ecosystem has increased recently as a result industrial wastewater loaded with organic contaminants, including methylene blue (MB), which exerts serious damage to environment. Thus, present work aims green synthesis silver nanoparticles (Ag-NPs) and evaluate their degradability notorious MB dye, well antimicrobial activities. Ag-NPs were synthesized by Cytobacillus firmus extract fully characterized UV-vis, TEM, DLS, XRD, FTIR. showed good antibacterial antifungal...
Multiple biological functions of Mentha pulegium extract were evaluated in the current work. Phytochemical components M. detected by Gas Chromatography-Mass Spectrometry (GC-MS) and High-performance liquid chromatography (HPLC). Moreover, was estimated for antioxidant potential 2,2-Diphenyl-1-picryl-hydrazyl-hydrate (DPPH) free radical scavenging, antimicrobial activity well diffusion, anticoagulant via prothrombin time (PT) activated partial thromboplastin (APTT). GC-MS analysis compounds...
Background: Wound infection is a prevalent concern in the medical field, being multi-step process involving several biological processes.Methicillin-resistant S. aureus (MRSA) and vancomycin-resistant (VRSA) infections often occur areas of damaged skin, such as abrasions open wounds.Methods: This research aims to light incidence MRSA VRSA wound swabs, antimicrobial susceptibility configuration isolated patterns pus/wound samples collected from Saudi Arabian tertiary hospital.The cross...
Despite the discovery of many plant-based drugs, research is still ingoing, in addition to using safer and more effective methods extraction process. Presently, Super Fluid Extraction (SFE) was applied extract mango seed kernels (MSK) at two operating temperatures 30 50 °C with studying their biological activities. MSK via SFE showed high yield 0.268 g compared that °C. High-performance liquid chromatography (HPLC) analysis demonstrated content compounds such as gallic acid (68503.01 µg/mL),...
This study explored the in vivo wound healing potential of Vitis vinifera seed extract using an excision model with focus on molecular targets including TGFBR1, VEGF, TNF-α, and IL-1β. The results revealed that V. enhanced closure rates (p < 0.001), elevated TGF-β VEGF levels, significantly downregulated TNF-α IL-1β levels comparison to Mebo®-treated group. phenotypical were supported by biochemical histopathological findings. Phytochemical investigation yielded a total 36 compounds...
There has been a substantial rise in the number of vancomycin-resistant Staphylococcus aureus (VRSA) strains during last several years. The proportion among isolated S. risen steadily recent years, with first spike occurring critical care units and thereafter general hospital wards. isolates from urinary tract infection patients were studied for their prevalence antibiotic resistance. From 292 urine samples, 103 bacterial (35.3%) identified as aureus. Various antibiotics used to test...
Hypervirulent Klebsiella pneumoniae (hvKp) is a new emerging variant of K. that increasingly reported worldwide. The hvKp known to cause severe invasive community-acquired infections such as metastatic meningitis, pyogenic liver abscesses (PLA) and endophthalmitis, but its role in hospital-acquired (HAIs) little known. aim this study was evaluate the prevalence among (HA) intensive care unit (ICU) compare between classical (cKP) regarding antimicrobial resistance pattern, virulence molecular...
The oxidative stress leading to degenerative changes in the brain of Alzheimer's disease (AD) is evident. Our aim was evaluate therapeutic and protective effects pomegranate extract (PE) extract-loaded nanoparticles (PE nano) an AlCl 3-induced AD rat model. Nanoparticles were synthesized with a PE load 0.68% w/w, 70 male Wistar rats divided into 7 groups: Group I control, II received PE., III nano for 2 weeks, IV 3 (50 mg/kg) daily orally 4 V VI Groups started after administration stopped....
A strain of Bacillus cereus was isolated from the Saudi Red Sea coast and identified based on culture features, biochemical characteristics, phylogenetic analysis 16S rRNA sequences. EPSR3 a major fraction exopolysaccharides (EPS) containing no sulfate had uronic acid (28.7%). The monosaccharide composition these fractions is composed glucose, galacturonic acid, arabinose with molar ratio 2.0: 0.8: 1.0, respectively. subjected to antioxidant, antitumor, anti-inflammatory activities. results...
It is thought to be risk-free, environmentally benign, and safe for biological processes produce zinc oxide nanoparticles from renewable resources. This study examined Cassia javanica’s ability create ZnONPs. The generated ZnONPs were analyzed using a variety of techniques, such as TEM, FTIR spectroscopy, UV-Vis XRD analysis. antibacterial potential has been investigated both Agar well diffusion microtitreplate (MTP) methods. One method used evaluate ZnONPs’ capacity scavenge free radicals...
Plants represent a great source of medicines, and for their components to be discovered, extraction processes must developed, especially methods based on green technology. Supercritical fluid (SFE) was employed as method Moringa oleifera in the present investigation. The maximum yield obtained at 25 MPa. Moreover, MPa induced release various phenols flavonoids, analyzed via high-performance liquid chromatography. investigation revealed concentrations chlorogenic, gallic, rosmarinic, coumaric...
Cinnamon is a plant with significant medicinal value that used extensively as spice, flavoring, and fragrance ingredient. Phytochemical characterization via high-performance liquid chromatography, antimicrobial activity against various microorganisms, anti-diabetic properties by α-glucosidase α-amylase assessments, antioxidant 2,2-diphenyl-1-picrylhydrazyl-hydrate, total capacities of cinnamon bark were evaluated. Moreover, antitumor potential human breast cancer (MCF-7) fetal lung...