A5064025539- Essential Oils and Antimicrobial Activity
- Hemoglobinopathies and Related Disorders
- Phytochemicals and Antioxidant Activities
- Nigella sativa pharmacological applications
- Nanoparticles: synthesis and applications
- Bee Products Chemical Analysis
- Date Palm Research Studies
- Pomegranate: compositions and health benefits
- Medicinal Plants and Neuroprotection
- Moringa oleifera research and applications
- Curcumin's Biomedical Applications
- Selenium in Biological Systems
- Antioxidants, Aging, Portulaca oleracea
- Bioactive Compounds and Antitumor Agents
- Iron Metabolism and Disorders
- Biochemical effects in animals
- Erythrocyte Function and Pathophysiology
- Antioxidant Activity and Oxidative Stress
- Neonatal Health and Biochemistry
- Natural Antidiabetic Agents Studies
- Acupuncture Treatment Research Studies
- Chemotherapy-induced organ toxicity mitigation
- Insect Pest Control Strategies
- Complementary and Alternative Medicine Studies
- Medicinal Plants and Bioactive Compounds
King Abdulaziz University
2016-2025
King Abdulaziz Hospital
2000-2024
Jouf University
2024
Palmetto Hematology Oncology
2022
New Cross Hospital
2022
King Abdul Aziz University Hospital
2003-2020
King Abdulaziz Medical City
2020
University of Jeddah
2018
King Saud University
2006-2017
Sunnybrook Health Science Centre
1990
In the current study, prickly pear peel waste (PPPW) extract was used for biosynthesis of selenium nanoparticles through a green and eco-friendly method first time. The biosynthesized SeNPs were characterized using UV-Vis, XRD, FTIR, TEM, SEM, EDX, mapping. Characterization results revealed that spherical, polydisperse, highly crystalline, had sizes in range 10-87.4 nm. Antibacterial, antifungal, insecticidal activities evaluated. Results exhibited promising antibacterial against Gram...
Gastric ulcers are among the most common diseases affecting humans. This study aimed at investigating gastroprotective effects of manuka honey against ethanol‐induced gastric in rats. The mechanism by which exerts its antiulcer potential was elucidated. Four groups rats were used: control, ethanol (ulcer), omeprazole, and honey. Stomachs examined macroscopically for hemorrhagic lesions glandular mucosa, histopathological changes, glycoprotein detection. oxidative stress investigated using...
Honey exhibits antimicrobial activities against a wide range of bacteria in different milieu. This study aims to compare the effects five types honey (both imported and local Saudi honey) Staphylococcus aureus. The (Manuka UMF +20, Manuka +16, Active +10 Honey, Sidr Nigella sativa were evaluated for their bactericidal/bacteriostatic both methicillin resistant sensitive S. inhibitory effect on bacterial growth was evident at concentrations 20% 10% (v/v). showed best results. +20 had...
Antioxidants have valuable effects on the process of spermatogenesis, particularly with diabetes mellitus (DM). Therefore, present study investigated impact and intracellular mechanisms by which thymoquinone (TQ) works against diabetes-induced testicular deteriorations in rats. Wistar male rats (n = 60) were randomly allocated into four groups; Control, Diabetic (streptozotocin (STZ)-treated where was induced intraperitoneal injection STZ, 65 mg/kg), + TQ (diabetic treated (50 mg/kg) orally...
Probiotic bacteria can confer health benefits to the human gastrointestinal tract. Lactic acid (LAB) are candidate probiotic that widely distributed in nature and be used food industry. The objective of this study is isolate characterize LAB present raw fermented milk Saudi Arabia. Ninety‐three suspected were isolated from thirteen different types indigenous animals identification forty‐six selected strains their genetic relatedness was performed based on 16S rDNA gene sequence comparisons....
The medicinal administration of Aloe vera gel has become promising in pharmaceutical and cosmetic applications particularly with the development nanotechnology concept. Nowadays, effective H. pylori treatment is a global problem; therefore, natural products nanopolymers such as chitosan nanoparticles (CSNPs) could represent novel strategy for gastric infection pylori. HPLC analysis A. indicated presence chlorogenic acid main constituent (1637.09 µg/mL) other compounds pyrocatechol µg/mL),...
Multiple biological functions of Mentha pulegium extract were evaluated in the current work. Phytochemical components M. detected by Gas Chromatography-Mass Spectrometry (GC-MS) and High-performance liquid chromatography (HPLC). Moreover, was estimated for antioxidant potential 2,2-Diphenyl-1-picryl-hydrazyl-hydrate (DPPH) free radical scavenging, antimicrobial activity well diffusion, anticoagulant via prothrombin time (PT) activated partial thromboplastin (APTT). GC-MS analysis compounds...
Oxidative stress results from the imbalance between reactive oxygen species (ROS) production and antioxidant defence is primarily involved in aging. The current study investigated activity of rutin aging rats induced by D-galactose (D-gal) for 42 days. Rutin was orally used at doses 50 100 mg kg-1 daily. Results showed that D-gal oxidative alterations brain liver recognized via upregulation markers. In contrast, ameliorated enhancing markers such as superoxide dismutase-1, glutathione...
(1) Background: Chitosan-gelatin-based thermosensitive hydrogel containing 5FU-alginate nanoparticles was formulated for the effective and sustained delivery of 5FU to skin. (2) Methods: Alginate, a polysaccharide used formulation using spray drying technique. Size, zeta potential, surface morphology were investigated zetasizer scanning electron microscope. The fabricated chitosan gelatin. Several important analyses characterize these prepared topical hydrogels. pH, visual transparency,...
Background: Wound infection is a prevalent concern in the medical field, being multi-step process involving several biological processes.Methicillin-resistant S. aureus (MRSA) and vancomycin-resistant (VRSA) infections often occur areas of damaged skin, such as abrasions open wounds.Methods: This research aims to light incidence MRSA VRSA wound swabs, antimicrobial susceptibility configuration isolated patterns pus/wound samples collected from Saudi Arabian tertiary hospital.The cross...
Despite the discovery of many plant-based drugs, research is still ingoing, in addition to using safer and more effective methods extraction process. Presently, Super Fluid Extraction (SFE) was applied extract mango seed kernels (MSK) at two operating temperatures 30 50 °C with studying their biological activities. MSK via SFE showed high yield 0.268 g compared that °C. High-performance liquid chromatography (HPLC) analysis demonstrated content compounds such as gallic acid (68503.01 µg/mL),...
Abstract Natural products of plant origin are being explored as safe alternatives for illness management. Their extraction processes play a crucial role in determining their phytochemical and pharmacological properties. In this context, Euphorbia trigona was extracted using Supercritical Fluid Extraction with CO 2 (SFE-CO ) at two operating temperatures: 20 °C 40 °C. Phytochemical characterization performed via HPLC, along anti-yeast evaluation the well diffusion method, anticancer...
A randomized double-blind clinical trial was performed to test the safety and efficacy of a low-molecular-weight heparin, tinzaparin (Innohep), for management acute painful vasoocclusive crisis characteristic sickle cell anemia (SCA). We studied 253 patients with but no other complications SCA, treatment or control groups. In group, 127 received at 175 IU/kg, subcutaneous once daily, along supportive care including morphine analgesia; in 126 placebo same care. The maximal experimental period...
Gastric ulcers are a major problem worldwide with no effective treatment. The objective of this study was to evaluate the use manuka honey in treatment acetic acid‐induced chronic gastric rats. Different groups rats were treated three different concentrations honey. Stomachs checked macroscopically for ulcerative lesions glandular mucosa and microscopically histopathological alterations. Treatment significantly reduced ulcer index maintained glycoprotein content. It also mucosal...
Diosgenin, a naturally occurring steroid saponin found abundantly in C. speciosus, is well-known precursor of various synthetic steroidal drugs that are extensively used the pharmaceutical industry.The present study was conducted to evaluate vitro anticancer and apoptotic effects on cell proliferation diosgenin isolated from speciosus (Koen.) Sm.The results indicated treatment HepG2 cells with sample resulted cytotoxic effect as concluded IC50 value 32.62 μg/ml, while paclitaxel, known...