- Fatty Acid Research and Health
- Hepatitis C virus research
- Hepatitis B Virus Studies
- Liver Disease Diagnosis and Treatment
- HIV Research and Treatment
- Hepatitis Viruses Studies and Epidemiology
- Cholesterol and Lipid Metabolism
- Diet, Metabolism, and Disease
- HIV/AIDS Research and Interventions
- Lipid metabolism and biosynthesis
- Peroxisome Proliferator-Activated Receptors
- Lipoproteins and Cardiovascular Health
- Diet and metabolism studies
- Systemic Lupus Erythematosus Research
- Nutritional Studies and Diet
- HIV, Drug Use, Sexual Risk
- Eicosanoids and Hypertension Pharmacology
- Cancer, Lipids, and Metabolism
- Infant Nutrition and Health
- Antioxidant Activity and Oxidative Stress
- HIV/AIDS drug development and treatment
- SARS-CoV-2 and COVID-19 Research
- T-cell and Retrovirus Studies
- Viral gastroenteritis research and epidemiology
- Liver Disease and Transplantation
Istituto Nazionale di Documentazione Innovazione e Ricerca Educativa
2024
National University of Tierra del Fuego
2020
Abbott (Germany)
2000-2019
University of Milan
2006-2017
University of Verona
2016
Azienda Sanitaria Locale Roma 3
2006-2015
University of Brescia
2011
Yale University
2011
Azienda Socio Sanitaria Territoriale degli Spedali Civili di Brescia
2011
Abbott (Sweden)
2010
<h3>Objective</h3> To investigate whether dietary supplementation with docosahexaenoic acid (DHA) decreases liver fat content in children non-alcoholic fatty disease (NAFLD). <h3>Design, setting and patients</h3> We performed a randomised controlled trial of DHA (250 500 mg/day) versus placebo 60 biopsy-proven NAFLD (20 per group). <h3>Main outcome measures</h3> The main was the change as detected by ultrasonography after 6 months treatment. Secondary outcomes were changes insulin...
HIV testing is crucial towards the control of Acquired Immune Deficiency Syndrome (AIDS) epidemic. Monitoring trends human immunodeficiency virus (HIV) over time may help interpret incidence new diagnoses and effectiveness strategies. We started a research project aimed at assessing rates for infection among Italian outpatients in 2018–2023. Numeric data screening, confirmatory, monitoring tests obtained by national register were compared with numbers adult residents, newly diagnosed...
Abstract Background: The aim of this work was to analyze the diagnostic and prognostic value serum human epididymis protein 4 (HE4) Risk for Ovarian Malignancy Algorithm (ROMA) in epithelial ovarian cancer (EOC). Methods: Preoperative samples 419 women (140 healthy controls, 131 benign cysts, 34 endometriosis, 114 EOC) were tested CA125 HE4 using fully automated methods (Abbott ARCHITECT) validated cutoff values. Results: For discrimination masses from EOC, premenopausal women, sensitivity...
Abstract Objectives Simple and standardized methods to establish correlates vaccine-elicited SARS-CoV-2 protection are needed. Methods An observational study on antibody response a mRNA vaccine (Comirnaty) was performed health care workers (V, n=120). Recovered COVID-19 patients (N, n=94) were used for comparison. Antibody evaluated by quantitative anti-receptor binding domain IgG (anti-RBD) commercial assay virus microneutralization test (MNT), in order threshold of anti-RBD units (BAU)...
Protein induced by vitamin K absence or antagonist-II (PIVKA-II) has been suggested as a serum biomarker for hepatocellular carcinoma (HCC) in Asian hepatitis B virus (HBV)-treated subjects but no studies tested it Caucasian cirrhotics long-term nucleos(t)ide analogues (NUCs)-treated. We assessed the detection accuracy of PIVKA-II alone combination with alpha-foetoprotein (AFP) patients under surveillance.This cross-sectional, single centre case-control study was conducted 212 NUC-treated...
We evaluated the precision and accuracy of a procedure for detecting recent human immunodeficiency virus (HIV) infections, specifically, avidity index (AI) calculated using method based on an automated AxSYM HIV 1/2gO assay (Abbott). To evaluate precision, we performed multiple replicates eight HIV-positive serum samples. in identifying infections (i.e., within 6 months seroconversion), used 216 samples from 47 persons whose dates seroconversion were known. sensitivity specificity different...
We evaluated a procedure for identifying recent HIV infections, using sequential serum samples from 47 HIV-positive persons whom the seroconversion date could be accurately estimated. Each sample was divided into two aliquots: one diluted with phosphate-buffered saline and other 1 M guanidine. assayed aliquots automated AxSYM HIV1/2gO test (Abbott Diagnostics Division), without modifying manufacturer's protocol. then calculated avidity index (AI): ratio of sample/cutoff value guanidine...
The purpose of this study was to assess the diagnostic and prognostic impact preoperative serum determination human epididymis protein 4 (sHE4), investigate its potential correlation with clinicopathological features survival endpoints in endometrial cancer patients.Preoperative samples from 193 patients 125 women normal endometrium were measured for sHE4 CA125 (sCA125) concentrations by quantitative chemiluminescent microparticle immunoassays on automated Architect instrument.sHE4...
We evaluated CA19-9 as a marker of various malignancies and compared the results 2 commercial immunoassays. The Abbott ARCHITECT i2000 Roche cobas 410 immunoassays were used on 500 consecutive samples to evaluate frequency positive by cancer type correlation between assays. patients tested before or after surgery and/or during chemotherapy. rate exceeding conventional thresholds was 92.3% in pancreatic cancer, 36.8% gastric ranged from 3.0% 35.9% other tumors. Agreement (90.6%) (R2 = 0.865)...