A5040980791- Congenital Heart Disease Studies
- Cardiac Structural Anomalies and Repair
- Nitric Oxide and Endothelin Effects
- Cardiac Valve Diseases and Treatments
- Mechanical Circulatory Support Devices
- Tracheal and airway disorders
- Transplantation: Methods and Outcomes
- Congenital Diaphragmatic Hernia Studies
- Aortic Disease and Treatment Approaches
- Cardiac Ischemia and Reperfusion
- Cardiac Arrest and Resuscitation
- Coronary Artery Anomalies
- Renal Transplantation Outcomes and Treatments
- Healthcare Policy and Management
- Congenital Anomalies and Fetal Surgery
- Cardiac Arrhythmias and Treatments
- Trauma Management and Diagnosis
- Intestinal and Peritoneal Adhesions
- Intestinal Malrotation and Obstruction Disorders
- Cardiovascular, Neuropeptides, and Oxidative Stress Research
- Cardiac and Coronary Surgery Techniques
- Cardiac, Anesthesia and Surgical Outcomes
- Renin-Angiotensin System Studies
- Viral Infections and Immunology Research
- Vascular anomalies and interventions
University of California, San Francisco
2018-2024
UCSF Benioff Children's Hospital
2020-2023
Rainbow Babies & Children's Hospital
2012-2017
Children's Hospital of Wisconsin
2016-2017
Medical College of Wisconsin
2016-2017
University Hospitals of Cleveland
2017
Case Western Reserve University
2017
Akron Children's Hospital
2016
University of Mississippi Medical Center
2016
Jackson Memorial Hospital
2016
Brief myocardial ischemia is associated with and coronary endothelial dysfunction caused by oxygen free radicals released during reperfusion. Estrogen, known to have antioxidant activity, may prevent these complications.We assessed the effect of 2 weeks treatment 17 beta-estradiol (E, 100 micrograms.kg-1.d-1, n = 12) or placebo (P, 15) on function first hours reperfusion in dogs subjected 15 minutes induced occlusion left anterior descending artery (LAD). Our results show that incidence...
To determine the incidence of left vocal fold paralysis (LVFP) in premature infants who undergo patent ductus arteriosus (PDA) ligation.Prospective cohort.The study was carried out newborn intensive care unit (NICU) a tertiary academic medical center. Eighty-six newborns underwent ligation PDA were examined postextubation with fiberoptic laryngoscopy to assess mobility, regardless laryngeal symptom status.Fourteen (16%) had LVFP. All <28 weeks postmenstrual age (PMA) at birth and <1,250 g...
Objective: Stentless porcine valves are commonly used for aortic valve replacement in adults, yet their long-term performance the right ventricular (RV) outflow tract is unknown. We evaluated intermediate-term of stentless RV 150 children and adults over a 10-year period. Methods: retrospectively reviewed data on all patients undergoing placement pulmonary or RV-PA conduit with prosthesis (≥19 mm) from 1998 to 2008. Valvar function was assessed echocardiography. Freedom reintervention...
Background With improving survival of patients with single ventricle physiology who underwent Fontan palliation, there is also an increase in the prevalence overweight and obesity these patients. This tertiary care single-center study aims to determine association body mass index (BMI) clinical characteristics outcomes adults Fontan. Methods Results Adult (aged ≥18 years) were managed at a center between January 1, 2000, July 2019, had BMI data available identified via retrospective review...
Objective: To evaluate the safety and long-term efficacy of innominate artery reimplantation as treatment for compression syndrome.
Abstract Short‐term mechanical circulatory support in the pediatric population with acute cardiac failure has traditionally been limited to extracorporeal membrane oxygenation given availability of pediatric‐sized pumps. The Levitronix CentriMag system (Thoratec Corporation, Pleasanton, CA, USA) offers expanded options for short‐term this population. We report our experience successful use as a bridge decision after postcardiotomy ventricular and recovery heart transplantation. first patient...
Wound complications after ventricular assist device (VAD) placement remain a formidable challenge to surgeons. The Berlin Heart EXCOR VAD is versatile pulsatile system that has been successful in pediatric patients of all ages and sizes. Prevention device-related such as infection, particularly patients, remains an essential issue minimizing patient morbidity mortality. introduction vacuum-assisted wound closure (VAC) therapy its application VAD-related provide efficient effective method for...
Background —Coronary endothelial dysfunction after brief ischemia-reperfusion (IR) remains a clinical problem. We investigated the role of heparin and N -acetylheparin, nonanticoagulant derivative, in modulating coronary function IR injury, with an emphasis on defining nitric oxide (NO)–cGMP pathway heparin-mediated effect. Methods Results —Male mongrel dogs were surgically instrumented, effects both bovine -acetylheparin vasomotor function, expressed as percent change from baseline flow...
We studied the effect of 2-week treatment with estradiol 17β on myocardial glutathione concentration in dogs and isolated perfused rat heart subjected to brief coronary ischemia reperfusion. Estradiol protected against ischemia/reperfusion-induced systolic shortening malonylaldehyde production increased glucose-6-phosphate dehydrogenase enzyme activity. Reduction buthionine sulfoximine levels seen absence estrogen reversed protective dysfunction lipid peroxidation associated...
Atrial fibrillation is one of the most frequent complications after cardiovascular surgery. It may result in thromboembolic events, hemodynamic deterioration, and an increased length cost hospitalization.We retrospectively studied 504 consecutive adult patients undergoing surgery to determine whether with new-onset postoperative atrial could be safely discharged ventricular rate had been controlled anticoagulation initiated.Postoperative occurred 79 (16.2%) 487 survivors. Of these patients,...
Objective To assess the authors’ hypothesis that with modern techniques, current risks of repair for both complete and partial atrioventricular canal (AVC) are equal. Summary Background Data Repair AVC in infancy has traditionally carried a substantial mortality. In contrast, been considered low-risk can be performed later childhood. Methods This was retrospective review 63 infants children who underwent (n = 40) or 23) from 1990 to 2001. Among patients, ventriculoseptal defect repaired via...
Although mortality following repair of subaortic obstruction is low, aggressive resection may increase morbidity. We sought to evaluate outcomes and risk atrioventricular heart block (AVB) after in the current era. Simple was defined as a discrete membrane complex multilevel or diffuse narrowing. Limited included membranectomy limited myomectomy. Aggressive Konno, modified Ross. Specified variables were obtained from chart review. The 185 consecutive patients (1991-2008) ranged age 1 day...