A5101426089- Lung Cancer Treatments and Mutations
- Endometrial and Cervical Cancer Treatments
- Lung Cancer Diagnosis and Treatment
- Pediatric Hepatobiliary Diseases and Treatments
- Cancer Genomics and Diagnostics
- Neuroendocrine Tumor Research Advances
- Respiratory Support and Mechanisms
- Genetic factors in colorectal cancer
- Cancer Treatment and Pharmacology
- Ovarian cancer diagnosis and treatment
- Thyroid Cancer Diagnosis and Treatment
- Chronic Obstructive Pulmonary Disease (COPD) Research
- Tuberous Sclerosis Complex Research
- Medical Imaging and Pathology Studies
- Cholangiocarcinoma and Gallbladder Cancer Studies
- Helicobacter pylori-related gastroenterology studies
- Radiopharmaceutical Chemistry and Applications
- Amyotrophic Lateral Sclerosis Research
- Cytokine Signaling Pathways and Interactions
- Vascular Tumors and Angiosarcomas
- Parkinson's Disease Mechanisms and Treatments
- Colorectal Cancer Screening and Detection
- Medical and Biological Ozone Research
- Nephrotoxicity and Medicinal Plants
- Cancer, Hypoxia, and Metabolism
Hiraka General Hospital
2021
Akita University
2015-2017
Kawasaki Medical School Hospital
2016
Shizuoka Cancer Center
2011
Okayama University
1993-1999
Iwate Medical University
1997
Kagawa University
1996
Yamagata University
1989
A study of the incidence Parkinson's disease was carried out in a Japanese city, and cases those who had died were studied to clarify longevity patients causes death. On day, April 1, 1980, total 101 with found be living investigated area, which population 125,291. The rate 80.6 per 100,000 population, average annual for period 1975 through 1979 10.2 year. age at death 70.0 years, mean duration illness 7.4 years. main heart diseases bronchopneumonia, complications long being bedridden.
Lynch syndrome (LS) is an autosomal-dominant inherited disorder mainly caused by a germline mutation in the DNA mismatch repair (MMR) genes (MLH1, MSH2, MSH6, and PMS2) associated with increased risk for various cancers, particularly colorectal cancer endometrial (EC). Women LS account 2% to 6% of EC patients; it clinically important identify such individuals predicting and/or preventing additional LS-associated cancers. PMS2 (PMS2-LS) rarest contribution etiology among 4 MMR mutations, its...
The antitumor effects of anti-PD-1 antibody against mismatch repair deficiency (MMR-D)-associated cancers have been reported. MMR-D is found in approximately 20%-30% endometrial carcinomas (ECs) and frequently occurs due to MLH1 promoter hypermethylation (MLH1-PHM). ECs with MLH1-PHM are classified according the molecular screening Lynch syndrome (LS), but few detailed reports available. purpose this study was clarify clinical features EC MLH1-PHM.Immunohistochemistry MMR proteins (MLH1,...
Low–tidal volume (Vt) ventilation might protect healthy lungs from volutrauma but lead to inflammation resulting other mechanisms, namely alveolar derecruitment and the ensuing collapse tidal reexpansion. We hypothesized that different mechanisms of low- high-volume injury would be reflected in mechanical properties being associated with development pulmonary mortality: an increase hysteresis, reflecting progressive derecruitment, at low Vt; elastance, as a result overdistension, higher Vt....
Endometrial cancer (EC) rates are rising in Japan. Lymph node (LN) metastasis is an important prognostic factor EC, and its risk increased with higher tumor grade, deep myometrial invasion, larger size, lymphovascular space invasion (LVSI). Current methodologies to assess these factors unreliable. We previously showed the association between C-reactive protein (CRP) 1846C>T (rs1205) polymorphism LN esophageal, non-small cell lung, breast cancers. The CRP gene located on chromosome 1q21-q23,...
A 75-year-old man with atrial fibrillation was hospitalized because of shortness breath triggered by upper respiratory infection and tachycardia. His symptoms were improved bed rest administration diuretics. Pretreatment echocardiogram reported dilatation the right ventricle (RV). Follow-up study performed before discharge. Apical four-chamber view still demonstrated remarkable RV (Fig. 1A). In one apical views, tricuspid valve showed a bridge-like appearance in systole without opening 1B C,...
A mass developing in operating scar part with fistula should raise concern for caseating granuloma even if many years after operation.