- Tuberculosis Research and Epidemiology
- COVID-19 Clinical Research Studies
- Long-Term Effects of COVID-19
- COVID-19 Prevention and Impact
- Pleural and Pulmonary Diseases
- Diagnosis and treatment of tuberculosis
- Advanced Glycation End Products research
- Infectious Diseases and Tuberculosis
- Congenital Diaphragmatic Hernia Studies
- Parasites and Host Interactions
- Blood groups and transfusion
- Inflammatory Biomarkers in Disease Prognosis
- Public Health and Nutrition
- Arabic Language Education Studies
- Vitamin D Research Studies
- COVID-19 diagnosis using AI
- Pneumothorax, Barotrauma, Emphysema
- SARS-CoV-2 and COVID-19 Research
- Scientific and Engineering Research Topics
- Congenital Anomalies and Fetal Surgery
- Amoebic Infections and Treatments
- Hydrogen's biological and therapeutic effects
- Sulfur Compounds in Biology
- Pancreatic and Hepatic Oncology Research
- Medical Imaging and Pathology Studies
Airlangga University
2018-2022
Universitas Dr. Soetomo
2022
The main target of SARS-CoV2 is the alveolar type II (AT2) cells lung. evades innate immune system resulting in release proinflammatory cytokines (IL-1β, IL-6, TNF-α) which causes AT2 cell damage. Krebs von den Lungen (KL-6) a specific biomarker KL-6 produced that are injured/regenerated.Research discusses role COVID-19 still being debated and not much has been done Indonesia.This study was an analytical with prospective design on 75 patients who were treated. Subjects divided into two large...
Coronavirus disease 2019 (COVID-19) is a new health problem discovered in thus requires biomarkers that can detect early tissue damage. Soluble receptor for advanced glycation end-products (sRAGE) biomarker be used to identify lung damage.Analyzing the association of serum sRAGE on COVID-19 severity.This study employed cross-sectional design with consecutive sampling method. It was conducted from May 2020-October 2021. The number participants this 145 which were divided into 2 groups...
The aim of the research is to analyze differences in subset T lymphocytes and NK cells at various degrees disease severity order be used stratification patients’ management predict outcomes for optimal treatment. study sample 123 patients with confirmed COVID-19 was classified based on degree severity: 50 mild severity, 34 moderate 39 severe critical who were subjected complete blood count lymphocyte subsets (CD3, CD4, CD8) Flowcytometry. There significant number CD 3 (p=0.000), CD4 CD8...
Tuberculosis (TB) is one of major health problems in the world, with high morbidity and mortality rates. According to Global Report 2015, Indonesia ranks as country 2nd highest number TB cases world. Airway was described a ‘gateway’ main pathogens, allergens particles from external environment. It has surveillance function that filtering beneficial non-beneficial antigens, including Mycobacterium tuberculosis (MTB) causative agent TB. MTB mucosal transmitted pathogen, infects human through...
Pleuropulmonary amoebiasis caused by complications of amoebic liver abscess (ALA) is rare. A 23 years old male, presented with shortness breath, cough yellowish phlegm, right chest pain, fever, bulging stomach, yellow eyes, and swelling both legs. Abdominal ultrasound CT scan thorax abdomen revealed fluidopneumothorax abscess. Serological testing leads to Entamoeba histolytica infection, which was treated metronidazole but no significant improvement on empyema size. Surgery performed after...
Pulmonary Tuberculosis is a chronic infection that caused by Mycobacterium tuberculosis (M.tb) and it still the major health problem worldwide. can induce oxidative stress. Some studies has proved active TB patients have an association with excessive stress which causes glutathione (GSH) level decrease free radicals increase. Glutathione facilitates control of M.TB intracellular bacterial growth in macrophages direct antimicrobial activity. N-acetylcysteine (NAC) thiol, precursor L-cysteine...
Bilateral primary spontaneous pneumothorax (PSP) is a rare case of lung disease. A 20-year-old man with complaint shortness breath suspected having PSP and tuberculosis. The patient underwent water seal drainage installation in both cavities, but showed no improvement. Multiple blebs were found after few days. wedge resection VATS became an option. had improved function the procedure. WSD lungs However, when trained for expansion, condition bad. After help on multiple blebs, significant...
Background: Prevalence of multi-drug resistant tuberculosis (MDR-TB) is increased by the time. In Indonesia, there were an estimated 1.9% new cases and 12% previously treated cases. Protection against Mycobacterium dependent on Th1 cell CD4+ that produced pro-inflammatory cytokines such as IFN-γ TNF-α. T regulators (Tregs) IL-10 anti- inflammatory cytokine function those cytokines. It believed immune suppression responsible for MDR-TB. The previous study showed impaired responses enhanced...
Mycobacterium tuberculosis that infected apoptotic macrophages is triggered by PGE2. Apoptosis suppresses the growth of bacteria, which shown in results acid-fast bacilli (AFB) sputum becomes a marker number bacteria. Analyzing association between serum PGE2 levels and positivity AFB patients. A cross-sectional study was carried out from August 2019–July 2020. Serum were collected participants. Data analysis used Chi-square test Spearman's correlation with p < 0.05. The average participants'...
At the end of 2019, an infectious disease was discovered, has spread rapidly throughout world, and become a pandemic called COVID-19. Several risk factors for COVID-19 infection are advanced age comorbid diseases. However, at beginning in Wuhan, China there were more patients with blood type A who confirmed positive than other types. The study aimed to analyze relationship between ABO severity characteristics Universitas Airlangga Hospital, Surabaya. This is retrospective study, using...